Sodium formaldehydesulfoxylate dihydrate
- CAS No.
- 6035-47-8
- Chemical Name:
- Sodium formaldehydesulfoxylate dihydrate
- Synonyms
- RONGALITE;SODIUM FORMALDEHYDE SULFOXYLATE;SODIUM FORMALDEHYDE SULPHOXYLATE;SODIUM HYDROXYMETHANESULFINATE DIHYDRATE;RONGALITE C;SODIUM FORMALDEHYDESULFOXALATE;RONGALIT;SODIUM HYDROXYMETHYLSULFINATE;Sodium sulfinomethanolate dihydrate;HYDROXYMETHANESULFINIC ACID SODIUM SALT
- CBNumber:
- CB0853952
- Molecular Formula:
- CH7NaO4S
- Molecular Weight:
- 138.11
- MOL File:
- 6035-47-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/3 15:34:43
| Melting point | 64-68 °C(lit.) |
|---|---|
| Density | 1.8 g/cm3 (20℃) |
| vapor pressure | 2.68 hPa (20 °C) |
| storage temp. | Store below +30°C. |
| solubility | alcohol: slightly soluble(lit.) |
| form | powder to crystal |
| color | White to Almost white |
| PH | 9.5-10.5 (100g/l, H2O, 20℃) |
| CAS DataBase Reference | 6035-47-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H341-H361d |
| Precautionary statements | P201-P308+P313 |
| Hazard Codes | Xn |
| Risk Statements | 31-68 |
| Safety Statements | 24/25-36/37 |
| WGK Germany | 3 |
| RTECS | PB0390000 |
| HS Code | 28311000 |
| Toxicity | LD50 orally in Rabbit: 6400 mg/kg |
Sodium formaldehydesulfoxylate dihydrate price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 8.06455 | Sodium formaldehydesulfoxylate hydrate (stabilised with sodium carbonate) for synthesis | 6035-47-8 | 1KG | ₹3250 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.06455 | Sodium formaldehydesulfoxylate hydrate (stabilised with sodium carbonate) for synthesis | 6035-47-8 | 100G | ₹4900 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.06455 | Sodium formaldehydesulfoxylate hydrate (stabilised with sodium carbonate) for synthesis | 6035-47-8 | 5KG | ₹11340 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.06455 | Sodium formaldehydesulfoxylate hydrate (stabilised with sodium carbonate) for synthesis | 6035-47-8 | 25KG | ₹40480 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.06455 | Sodium formaldehydesulfoxylate hydrate (stabilised with sodium carbonate) for synthesis | 6035-47-8 | 50KG | ₹58500 | 2022-06-14 | Buy |
Sodium formaldehydesulfoxylate dihydrate Chemical Properties,Uses,Production
Chemical Properties
white crystalline powder
Uses
Pharmaceutic aid (preservative).
Production Methods
Sodium formaldehyde sulfoxylate is manufactured from sodium dithionate and formaldehyde in water.
General Description
Oxidation reation of hydroxymethanesulfinic acid with chlorite has been studied in the pH range 4-8. It is a sulfur-containing reducing agent.
Pharmaceutical Applications
Sodium formaldehyde sulfoxylate is a water-soluble antioxidant and is generally used as the dihydrate. It is used in the formulation of injection products at a level of up to 0.1% w/v in the final preparation administered to the patient.
Safety
The toxicological properties of sodium formaldehyde sulfoxylate
have not been fully investigated. However, it is used in the
formulation of injection products at a level to 0.1% w/v in the
final preparation administered to the patient.
Sodium formaldehyde sulfoxylate is moderately toxic by
ingestion, and when heated to decomposition it emits toxic fumes
of sulfur dioxide and sodium oxide.
LD50 (mouse, oral): 4 g/kg
LD50 (rat, IP): >2 g/kg
LD50 (rat, oral): >2 g/kg
storage
Store in well-closed, light-resistant containers at controlled room temperature (15–30℃).
Incompatibilities
Sodium formaldehyde sulfoxylate is incompatible with strong oxidizing agents; it is decomposed by dilute acid.
Regulatory Status
Included in the FDA Inactive Ingredients Database (parenteral products up to 0.1% via the IM, IV, and SC routes). Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Sodium formaldehydesulfoxylate dihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1681 | 43 | Inquiry |
| Scientific OEM | +91-22- 2343 7546 / 2341 3094 | New Delhi, India | 1996 | 38 | Inquiry |
| Biokemix | +91 (40) 6662-6366 | New Delhi, India | 487 | 50 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| FINAR LTD | +91 - 2717 - 616717 | New Delhi, India | 660 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Gupta Chemicals | 08048974525 | Delhi, India | 19 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +86-13288715578 +8613288715578 | China | 12463 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| ALPHA CHEMIKA | 43 |
| Scientific OEM | 38 |
| Biokemix | 50 |
| CLEARSYNTH LABS LTD. | 58 |
| FINAR LTD | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Triveni chemicals | 58 |
| Central Drug House(P) Ltd. | 58 |
| Gupta Chemicals | 58 |
| Hebei Mojin Biotechnology Co., Ltd | 58 |