ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Leucine derivatives >PROTEASOME INHIBITOR I

PROTEASOME INHIBITOR I

PROTEASOME INHIBITOR I Structure
CAS No.
158442-41-2
Chemical Name:
PROTEASOME INHIBITOR I
Synonyms
PSI;N-Cb;CS-1340;Z-IE(OTBU)AL-CHO;PROTEASOME INHIBITOR I;ProteasoMe Inhibitor 1;PROTEASOME INHIBITOR PSI;M.W. 618.77 C32H50N4O8;Z-ILE-GLU(OBUT)-ALA-LEU-H;Z-ILE-GLU(OTBU)-ALA-LEU-CHO
CBNumber:
CB8781378
Molecular Formula:
C32H50N4O8
Molecular Weight:
618.76
MOL File:
158442-41-2.mol
MSDS File:
SDS
Modify Date:
2024/10/22 21:07:33

PROTEASOME INHIBITOR I Properties

Boiling point 844.2±65.0 °C(Predicted)
Density 1.121±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility ≥30.6 mg/mL in DMSO; insoluble in H2O; ≥48.7 mg/mL in EtOH
form solid
pka 11.12±0.46(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

WGK Germany  3

PROTEASOME INHIBITOR I Chemical Properties,Uses,Production

Uses

Proteasome Inhibitor 1, is a drug that blocks the action of proteasomes, protein complexes that degrade unneeded and damaged proteins. It is also shown to be used for the treatment of cancer, especially multiple myeloma. Proteasome inhibitors also induce apoptosis and reduce viral replication in primary effusion lymphoma cells.

PROTEASOME INHIBITOR I Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 92)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
Adroid Corporation 08068979845Ext 847 Pune, India 1 58 Inquiry
Alpha Biopharmaceuticals Co., Ltd +86-15542445688 China 888 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32038 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30241 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 23325 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19908 58 Inquiry
TargetMol Chemicals Inc. United States 38463 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49979 58 Inquiry
Nanjing TGpeptide +86-13347807150 +86-13347807150 China 3279 58 Inquiry

PROTEASOME INHIBITOR I Spectrum

CARBOBENZOXY-L-ISOLEUCYL-GAMMA-T-BUTYL-L-GLUTAMYL-L-ALANYL-L-LEUCINAL BENZYLOXYCARBONYL-L-ISOLEUCYL-[(2S)-2-AMINO-4-(T-BUTYLOXYCARBONYL)BUTANOYL]-L-ALANYL-L-LEUCINAL PROTEASOME INHIBITOR I PROTEASOME INHIBITOR I (ALDEHYDE) PROTEASOME INHIBITOR PSI PSI N-CBZ-ILE-GLU(O-T-BUTYL)-ALA-LEUCINAL Z-IE(OTBU)AL-CHO Z-ILE-GLU(OBUT)-ALA-LEU-H Z-ILE-GLU(OBUT)-ALA-LEU-H (ALDEHYDE) Z-ILE-GLU(OTBU)-ALA-LEU-ALDEHYDE Z-ILE-GLU(OTBU)-ALA-LEU-CHO z-ile-glu(o-t-butyl)-ala-leucinal Z-ILE-GLU(OTBU)-ALA-LEUCINAL N-carbobenzyloxy-Ile-Glu(O-tert-butyl)-Ala-leucinal M.W. 618.77 C32H50N4O8 arbobenzoxy-l-isoleucyl-gamma-t-butyl-l-glutamyl-l-alanyl-l-leucinal N-Cb L-AlaninaMide, N-[(phenylMethoxy)carbonyl]-L-isoleucyl-L-a-glutaMyl-N-[(1S)-1-forMyl-3 -Methylbutyl]-, 1,1-diMethylethyl ester ProteasoMe Inhibitor 1 PSI PROTEASOME INHIBITOR I N-[(Phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-tert-butylester-N-[(1S)-1-formyl-3-methylbutyl]-L-alaninamide PROTEASOME INHIBITOR I ;Z-ILE-GLU(OTBU)-ALA-LEU-CHO CS-1340 L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-N-[(1S)-1-formyl-3-methylbutyl]-, 1,1-dimethylethyl ester PROTEASOME INHIBITOR I USP/EP/BP Cbz-Ile-Glu(OtBu)-Ala-Leu-al CBZ-Ile-Glu(OtBu)-Ala-Leu-aldehyde N-[(Phenylmethoxy)carbonyl]-L-isoleucyl-L-α-glutamyl-tert-butylester-N-[(1S)-1-formyl-3-methylbutyl]-L-alaninamide HBL6 cells,Inhibitor,apoptosis,PSI,Proteasome Inhibitor1,Proteasome Inhibitor 1,Primary effusion lymphoma (PEL),BC3 cells,KSHV,inhibit,Proteasome Inhibitor-1,NF-κB,Proteasome 158442-41-2 C32H50N4O8 Calpain and Proteasome Inhibitors Intracellular Protein Degradation Nitric Oxide and Cell Stress Caspases/Apoptosis Calpain and Proteasome Inhibitors Intracellular Protein Degradation Aldehydes Bioactive Small Molecules Building Blocks C13-C60 Carbonyl Compounds Cell Biology Cell Signaling and Neuroscience Chemical Synthesis Nitric Oxide and Cell Stress Organic Building Blocks Z Pepetides ProteasomeInhibitors peptides