4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE
![4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE Structure](CAS/GIF/191034-25-0.gif)
- CAS No.
- 191034-25-0
- Chemical Name:
- 4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE
- Synonyms
- 049;L-168;L-168,049;4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE;Pyridine, 4-[3-(5-bromo-2-propoxyphenyl)-5-(4-chlorophenyl)-1H-pyrrol-2-yl]-
- CBNumber:
- CB8842589
- Molecular Formula:
- C24H20BrClN2O
- Molecular Weight:
- 467.79
- MOL File:
- 191034-25-0.mol
- Modify Date:
- 2024/7/2 8:55:39
Boiling point | 542.3±50.0 °C(Predicted) |
---|---|
Density | 1.367±0.06 g/cm3(Predicted) |
storage temp. | Store at RT |
solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
form | Light beige solid |
pka | 13.99±0.50(Predicted) |
color | Light yellow to yellow |
4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE price More Price(1)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 346003 | Glucagon Receptor Antagonist II - CAS 191034-25-0 - Calbiochem The Glucagon Receptor Antagonist II, also referenced under CAS 191034-25-0, controls the biological activity of Glucagon Receptor. | 191034-25-0 | 5MG | ₹16670.01 | 2022-06-14 | Buy |
Product number | Packaging | Price | Buy |
---|---|---|---|
346003 | 5MG | ₹16670.01 | Buy |
4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE Chemical Properties,Uses,Production
Uses
L- is a potent (Kb = 25 nM), selective antagonist of glucagon.
Biological Activity
Very potent and selective, non-competitive antagonist of the human glucagon receptor (hGR). Binds with high affinity to human GR (IC 50 = 3.7 nM), and moderate affinity to murine and canine GRs (IC 50 values are 63 and 60 nM respectively). In contrast, displays poor affinity for rat, guinea pig, and rabbit glucagon receptors (IC 50 > 1 μ M). In functional studies, inhibits glucagon-stimulated cAMP synthesis in CHO cells expressing hGR (IC 50 = 41 nM), and in murine liver membranes. Orally active in vivo .
4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE Suppliers
Global( 24)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
Shanghai Changyu Medical Technology Co. Ltd. | +86-13301875428 | China | 300 | 58 | Inquiry |
Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4296 | 55 | Inquiry |
Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | China | 9943 | 58 | Inquiry |
Shanghai Maclean Biochemical Technology Co., LTD | 021-50706066 15221275939 | China | 29802 | 58 | Inquiry |
Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | China | 48465 | 58 | Inquiry |
Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | China | 2987 | 58 | Inquiry |
InvivoChem | 13549236410 | China | 6755 | 58 | Inquiry |
191034-25-0(4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE)Related Search:
4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE
L-168,049
Pyridine, 4-[3-(5-bromo-2-propoxyphenyl)-5-(4-chlorophenyl)-1H-pyrrol-2-yl]-
049
L-168
191034-25-0
C24H20BrClN2O
Glucagon receptor and related