4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE

CAS No.: 191034-25-0

Chemical Name:: 4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE

Synonyms: 049;L-168;L-168,049;4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE;Pyridine, 4-[3-(5-bromo-2-propoxyphenyl)-5-(4-chlorophenyl)-1H-pyrrol-2-yl]-

CBNumber:: CB8842589

Molecular Formula:: C24H20BrClN2O

Molecular Weight:: 467.79

MOL File:: 191034-25-0.mol

Modify Date:: 2024/7/2 8:55:39

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4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE Properties

Boiling point	542.3±50.0 °C(Predicted)
Density	1.367±0.06 g/cm3(Predicted)
storage temp.	Store at RT
solubility	Soluble to 100 mM in DMSO and to 100 mM in ethanol
form	Light beige solid
pka	13.99±0.50(Predicted)
color	Light yellow to yellow

4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	346003	Glucagon Receptor Antagonist II - CAS 191034-25-0 - Calbiochem The Glucagon Receptor Antagonist II, also referenced under CAS 191034-25-0, controls the biological activity of Glucagon Receptor.	191034-25-0	5MG	₹16670.01	2022-06-14	Buy

Product number	Packaging	Price	Buy
346003	5MG	₹16670.01	Buy

4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE Chemical Properties,Uses,Production

Uses

L- is a potent (Kb = 25 nM), selective antagonist of glucagon.

Biological Activity

Very potent and selective, non-competitive antagonist of the human glucagon receptor (hGR). Binds with high affinity to human GR (IC 50 = 3.7 nM), and moderate affinity to murine and canine GRs (IC 50 values are 63 and 60 nM respectively). In contrast, displays poor affinity for rat, guinea pig, and rabbit glucagon receptors (IC 50 > 1 μ M). In functional studies, inhibits glucagon-stimulated cAMP synthesis in CHO cells expressing hGR (IC 50 = 41 nM), and in murine liver membranes. Orally active in vivo .

4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE Suppliers

Global( 24)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32836	60	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Shanghai Changyu Medical Technology Co. Ltd.	+86-13301875428	China	300	58	Inquiry
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266	China	4296	55	Inquiry
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	China	9943	58	Inquiry
Shanghai Maclean Biochemical Technology Co., LTD	021-50706066 15221275939	China	29802	58	Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	China	48465	58	Inquiry
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	China	2987	58	Inquiry
InvivoChem	13549236410	China	6755	58	Inquiry

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Shanghai Changyu Medical Technology Co. Ltd.	58
Shanghai Lollane Biological Technology Co.,Ltd.	55
Shanghai Chaolan Chemical Technology Center	58
Shanghai Maclean Biochemical Technology Co., LTD	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	58
Shanghai Rechem science Co., Ltd.	58
InvivoChem	58

191034-25-0(4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE)Related Search:

2,4-Diphenylpyrrole 4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE

4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE L-168,049 Pyridine, 4-[3-(5-bromo-2-propoxyphenyl)-5-(4-chlorophenyl)-1H-pyrrol-2-yl]- 049 L-168 191034-25-0 C24H20BrClN2O Glucagon receptor and related