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1,3-Benzodioxole-5-acetic acid methyl ester

1,3-Benzodioxole-5-acetic acid methyl ester Structure
CAS No.
326-59-0
Chemical Name:
1,3-Benzodioxole-5-acetic acid methyl ester
Synonyms
NSC 105308;ASISCHEM D13375;Methyl 1,3-Benzodioxole-5-acetate;Methyl 1,3-benzodioxol-5-ylacetate;methyl2-(1,3-benzodioxol-5-yl)acetate;Methyl 2-(1,3-dioxaindan-5-yl)acetate;Methyl 4,5-(Methylenedioxy)phenylacetate;Methyl (3,4-Methylenedioxyphenyl)acetate;Methyl 2-(2H-1,3-benzodioxol-5-yl)acetate;Methyl 2-(benzo[d][1,3]dioxol-5-yl)acetate
CBNumber:
CB8847625
Molecular Formula:
C10H10O4
Molecular Weight:
194.18
MOL File:
326-59-0.mol
Modify Date:
2023/8/14 17:23:18
Request For Quotation

1,3-Benzodioxole-5-acetic acid methyl ester Properties

Boiling point 278.3℃
Density 1.265
refractive index 1.5430 (estimate)
Flash point 120.0℃
InChI InChI=1S/C10H10O4/c1-12-10(11)5-7-2-3-8-9(4-7)14-6-13-8/h2-4H,5-6H2,1H3
InChIKey HEMYXNDMAAOTCK-UHFFFAOYSA-N
SMILES O1C2=CC=C(CC(OC)=O)C=C2OC1

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H335-H315
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
HazardClass  IRRITANT

1,3-Benzodioxole-5-acetic acid methyl ester Chemical Properties,Uses,Production

Uses

Methyl 1,3-benzodioxol-5-ylacetate is a reagent used to prepare pharmaceutically active Benzodioxole derivatives.

Preparation

1,3-Benzodioxole-5-acetic acid methyl ester is a lignan synthesized by the condensation of podophyllotoxin with acetone in the presence of an acid catalyst.

Mode of action

1,3-Benzodioxole-5-acetic acid methyl ester is a regioselective inhibitor of 5α→5β conversion. This inhibition leads to a decrease in the production of diene metabolites that may be carcinogenic, as well as a decrease in the production of podophyllotoxin and its derivatives (podophyllum alkaloids). It has been shown to have anti-inflammatory properties and to inhibit prostaglandin synthesis.

1,3-Benzodioxole-5-acetic acid methyl ester Preparation Products And Raw materials

Raw materials

Acetone Podophyllotoxin

Preparation Products

1,3-Benzodioxole-5-acetic acid methyl ester Suppliers

Global( 41)Suppliers
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CHEMSWORTH +91-261-2397244 New Delhi, India 6700 30 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
Shanghai Worldyang Chemical Co.,Ltd. +86-021-56795779 +8613651600618 China 1073 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 7724 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10473 58 Inquiry
Shanghai Synchem Pharma Co., Ltd +86-61984905-1 +86-18016477331 China 92 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49734 58 Inquiry
Hebei Best Biological Technology Co., Ltd China 272 58 Inquiry
Hebei Miaoyin Technology Co.,Ltd +86-17367732028 +86-17367732028 China 3512 58 Inquiry
Xiamen Wonderful Bio Technology Co., Ltd. +8613043004613 China 283 58 Inquiry
Supplier Advantage
CHEMSWORTH 30
A.J Chemicals 58
Shanghai Worldyang Chemical Co.,Ltd. 58
Shaanxi Dideu Medichem Co. Ltd 58
Zhejiang J&C Biological Technology Co.,Limited 58
Shanghai Synchem Pharma Co., Ltd 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
Hebei Best Biological Technology Co., Ltd 58
Hebei Miaoyin Technology Co.,Ltd 58
Xiamen Wonderful Bio Technology Co., Ltd. 58

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BENZO[1,3]DIOXOL-5-YL-ACETIC ACID METHYL ESTER ASISCHEM D13375 1,3-Benzodioxole-5-acetic Acid Methyl Ester Methyl 2-(2H-1,3-benzodioxol-5-yl)acetate [3,4-(Methylenedioxy)phenyl]acetic Acid Methyl Ester Methyl (3,4-Methylenedioxyphenyl)acetate Methyl 1,3-Benzodioxole-5-acetate Methyl 4,5-(Methylenedioxy)phenylacetate NSC 105308 Methyl 1,3-benzodioxol-5-ylacetate methyl2-(1,3-benzodioxol-5-yl)acetate METHYL 1,3-BENZODIOXOL-5-YLACETATE ISO 9001：2015 REACH Methyl 2-(1,3-dioxaindan-5-yl)acetate Methyl 2-(benzo[d][1,3]dioxol-5-yl)acetate 326-59-0 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals intermediate