cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate

cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate Structure
CAS No.
61397-56-6
Chemical Name:
cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate
Synonyms
CIS-BBD;CIS Bromo;3-dioxalane];CIS-BROMO-ESTER;CIS-BROMO BENZOATE;Dapoxetine Impurity L;Cis-Bromobenzoate cis-;Cis Bromobenzoate (CBB);Cis-bromo-ester(Cis-BBD);Itraconazole Impurity 38
CBNumber:
CB8855189
Molecular Formula:
C18H15BrCl2O4
Molecular Weight:
446.12
MOL File:
61397-56-6.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate Properties

Melting point 116-117 °C(Solv: ethanol (64-17-5))
Boiling point 517.0±50.0 °C(Predicted)
Density 1.512±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
color White
Water Solubility 12μg/L at 20℃
LogP 5.8
CAS DataBase Reference 61397-56-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H312-H315-H319
Precautionary statements  P280-P305+P351+P338

cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

cis-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl Benzoate is an intermediate in the preparation of antifungal agents such as Ketoconazole (K186000), Itraconazole (I937500) and Tercon azole.

cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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CIS-BBD Cis-[(2-Bromomethyl)-2(2,4-Dichlorophenyl)-1,3-Dioxolan-4-Yl] Methyl Benxoate Cis-bromo-ester(Cis-BBD) CIS -BROMOBENZOATE:CIS -[2-BROMOMETHYL-2-(2,4-DICHLOROPHENYL)-1,3-DIOXOLAN-4-YL]METHYL BENZOATE CIS-BROMO-ESTER [CIS-2-(2,4-DICHLOROPHENYL)-2-BROMOMETHYL-4-(BENZOYLOXY)-METHYL-1,3-DIOXALANE] CisBromoBenzoateItraconazole CIS -[2-BROMOMETHYL-2-(2,4-DICHLOROPHENYL)-1,3-DIOXOLAN-4-YL]METHYL BENZOATE /CIS -BROMOBENZOATE (Z)-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-ylmethyl benzoate ((3S,5R)-5-(BROMOMETHYL)-5-(2,4-DICHLOROPHENYL)TETRAHYDROFURAN-3-YL)METHYL BENZOATE cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-methanolbenzoate 3-dioxalane] 4-Dichlorophenyl)-2-broMoMethyl-4-(benzoyloxy)-Methyl-1 cis-BroMo-ester [cis-2-(2 (2R,4R)-rel-2-(BroMoMethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-Methanol Benzoate Cis- 2-BroMoMethyl-2-(2,4-Dich... 1,3-Dioxolane-4-Methanol,2-(broMoMethyl)-2-(2,4-dichlorophenyl)-, 4-benzoate, (2R,4R)-rel- ((2R,4S)-2-(bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl benzoate Cis-Bromobenzoate cis- Cis-2-bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-methanolbenzoate [(2s,4s)-2-(bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]methyl benzoate 1,3-DIOXOLANE-4-METHANOL, 2-(BROMOMETHYL)-2-(2,4-DICHLOROPHENYL)-BENZOATE,(2R,4R)-REL- CIS-2-[2,4-DICHLOROPHENYL]-2-BROMOMETHYL-4-(BENZOYLOXY)METHYL-1,3-DIOXALANE CIS-[2-BROMOMETHYL-2-(2,4-DICHLOROPHENYL)-1,3-DIOXOLAN-4-YL]METHYL BENZOATE cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate CIS-BROMO BENZOATE CIS-BROMO-ESTER ((2R,4R)-2-(bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl benzoate Dapoxetine hydrochloride Impurity L Cis-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl] Cis bromo benzoate (int of ketoconazole and many other) () 2-[2-(bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl]benzoic acid methyl ester CIS Bromo Itraconazole Impurity 38 cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate ISO 9001:2015 REACH TIANFU CHEM----cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate Cis Bromo Benzoate (cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate)-S cis-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3-dioxola CIS-2-(BROMOMETHYL)-2-(2,4DICHLORO PHENYL)-1,3-DIOXOLANE-4-YLMETHYL BENZOATE(CIS BROMO BENZOATE) Cis Bromobenzoate (CBB) Dapoxetine Impurity L Ketoconazole Impurity 43 Cis-(2-(2,bromomethyl)-2-(-2,4- -Oichlrophenyl)-1,3-Dioxolan-4- yl}methyl benzoate CI2-2-(BROMOMETHYL)-2-(2,4 DICHLOROPHENYL)-1,3-DIOXOLAN E-4-YLMETHYL BENZOATE cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate(50 GMS) cis-2-(Bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-ylmethyl benzoate (10GMS) cis-[2-Bromomethyl-2-(2,4-dichlorophenyl) cis-[2-Bromomethyl-2-(2,4-dichlorophenyl)-1,3- dioxolan-4-yl]methyl Benzoate(CBB) Rel-((2R,4R)-2-(bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl benzoate 61397-56-6 6397-68-5 C18H15BrCl2O4 Pharmaceutical Intermediates