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10-methoxy-6-methylergoline-8beta-methanol

10-methoxy-6-methylergoline-8beta-methanol Structure
CAS No.
35121-60-9
Chemical Name:
10-methoxy-6-methylergoline-8beta-methanol
Synonyms
10α-Methoxy-9,10-dihydrolysergol;N-2 to API;Nicergoline Impurity 1;Nicergoline Impurity 11;Nicergoline Impurity 25; Nicergoline Impurity 16;Nicergoline EP Impurity 11;10-methoxy-9,10-dihydrolysergol;NicergolineEPImpurityC-N1-13C-d3;10-a-Methoxy-9,10-dihydrolysergol
CBNumber:
CB8898915
Molecular Formula:
C17H22N2O2
Molecular Weight:
286.38
MOL File:
35121-60-9.mol
Modify Date:
2023/5/4 15:14:36

10-methoxy-6-methylergoline-8beta-methanol Properties

Melting point 150-152°C (dec.)
Boiling point 456.8±45.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
vapor pressure 0.002Pa at 20℃
storage temp. Refrigerator
solubility Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
pka 14.87±0.10(Predicted)
form Solid
color Pale Orange to Light Brown
Water Solubility 440mg/L at 20℃
LogP -3.1 at 19.8℃

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H412-H371
Precautionary statements  P264-P270-P301+P312-P330-P501-P273-P501-P260-P264-P270-P309+P311-P405-P501

10-methoxy-6-methylergoline-8beta-methanol Chemical Properties,Uses,Production

Chemical Properties

Light Brown Solid

Uses

10α-Methoxy-9,10-dihydrolysergol is a derivative of Lysergol and Dehydrolysergol-I which act as partial agonists and antagonists at 5-HT2A, 5-HT2C and 5-HT1B receptors, and at α1-andrenergic receptors.

10-methoxy-6-methylergoline-8beta-methanol Preparation Products And Raw materials

Raw materials

Preparation Products

10-methoxy-6-methylergoline-8beta-methanol Suppliers

10-methoxy-6-methylergoline-8beta-methanol 10-methoxy-9,10-dihydrolysergol 10-Methoxy-6-methylergoline-8β-methanol [(6aR,9R,10aS)-10a-methoxy-7-methyl-4,6,6a,8,9,10-hexahydroindolo[4,3-fg]quinoline-9-yl]methanol N-2 to API Nicergoline Impurity 1 10-a-Methoxy-9,10-dihydrolysergol Ergoline-8-methanol, 10-methoxy-6-methyl-, (8β)- 10-a-Methoxy-9,10-dihydrolysergol hemiformate salt ((6aR,9R,10aS)-10a-methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol Nicergoline Impurity 11 10α-Methoxy-9,10-dihydrolysergol D4 Nicergoline Impurity 16 10α-Methoxy-9,10-dihydrolysergol NicergolineEPImpurityC-N1-13C-d3 Nicergoline Impurity 25 ((6aR,9R,10aS)-10a-Methoxy-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)methanol (Nicergoline Impurity) (8beta)-10-Methoxy-6-methylergolin-8-yl]methanol Nicergoline EP Impurity 11 35121-60-9 Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals