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clometacin

clometacin Structure
CAS No.
25803-14-9
Chemical Name:
clometacin
Synonyms
C1656;C-1656;C 1656;R 3959;Duperan;C017136;clometacin;3-(4-Chlorobenzoyl)-6-methoxy-2-methylindole-1- acetic acid;1H-Indole-1-acetic acid, 3-(4-chlorobenzoyl)-6-methoxy-2-methyl-;2-(3-(4-chlorobenzoyl)-6-methoxy-2-methyl-1H-indol-1-yl)acetic acid
CBNumber:
CB8903174
Molecular Formula:
C19H16ClNO4
Molecular Weight:
357.791
MOL File:
25803-14-9.mol
Modify Date:
2023/5/4 17:34:36
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clometacin Properties

Melting point 242°
Boiling point 564.0±50.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
pka 4.04±0.10(Predicted)

clometacin Chemical Properties,Uses,Production

Uses

Clometacin is an antalgic drug that binds to human serum albumin (HSA) and inhibits the binding of indomethacin, warfarin, clofibrate and salicylic acid to HSA.

World Health Organization (WHO)

Clometacin, an analogue of indometacin, was introduced on the market in 1971. Subsequently several cases of severe - in some cases fatal - hepatitis were reported, which led in 1987 to the withdrawal of a high-dosage tablet formulation, while the indications for a lower dosage tablet were restricted and duration of the treatment was limited. Eventually all tablet formulations were removed from the market. Clometacin is not widely registered in other countries.

clometacin Preparation Products And Raw materials

Raw materials

Phosphorus oxychloride Benzyl 2-chloroacetate Potassium hydroxide Phosphorus oxychloride

Preparation Products

clometacin Suppliers

Global( 7)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Shanghai Peiling Biological Technology Co., LTD 13127581762 China 439 58 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Debye Scientific Corporation 00852-2521 1836 China 6891 50 Inquiry
United States Biological 800.520.3011 or 781.639.5092 United States 6256 80 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
TargetMol Chemicals Inc. 58
Shanghai Peiling Biological Technology Co., LTD 58
Lanospharma Laboratories Co.,Ltd 56
Debye Scientific Corporation 50
United States Biological 80

25803-14-9(clometacin)Related Search:

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6-Methoxy-1H-indole-3-carbaldehyde (3-FORMYL-2-METHYL-INDOL-1-YL)-ACETIC ACID ASISCHEM W99822 1-(1-ETHYL-1H-INDOL-3-YL)ETHANONE 2,3-DIMETHYL-6-METHOXYINDOLE
6-METHOXY-1-METHYL-1H-INDOLE-3-CARBALDEHYDE N-Acetic acid-indole-3-carboxaldehyde 3-Acetyl-6-methoxyindole clometacin
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3-(4-Chlorobenzoyl)-6-methoxy-2-methylindole-1- acetic acid C017136 2-(3-(4-chlorobenzoyl)-6-methoxy-2-methyl-1H-indol-1-yl)acetic acid clometacin 1H-Indole-1-acetic acid, 3-(4-chlorobenzoyl)-6-methoxy-2-methyl- C 1656 C1656 C-1656 Duperan R 3959 25803-14-9