Sevelamer

Sevelamer Structure
CAS No.
52757-95-6
Chemical Name:
Sevelamer
Synonyms
Hsdb 7608;Sevelamer;Sevelamer [inn:ban];Epichlorohydrin-PAA 25 copolymer;Allylamine-epichlorohydrin copolymer;Allylamine polymer with 1-chloro-2,3-epoxypropane;2-Propen-1-amine, polymer with (chloromethyl)oxirane;Oxirane, (chloromethyl)-, polymer with 2-propen-1-amine
CBNumber:
CB91106827
Molecular Formula:
C6H12ClNO
Molecular Weight:
149.62
MOL File:
52757-95-6.mol
MSDS File:
SDS
Modify Date:
2023/5/21 10:59:17

Sevelamer Properties

storage temp. Store at -20°C
solubility Soluble in DMSO

Sevelamer Chemical Properties,Uses,Production

Uses

Antihyper-phosphatemic.

brand name

Renagel (Genzyme).

Pharmaceutical Applications

In patients on dialysis, Sevelamer or lanthanum salts can be used to maintain normal phosphate blood levels. Sevelamer is a polymer containing amine groups. These protonated amine groups can react with the negatively charged phosphate groups via ionic binding and prevent absorption of phosphate from the gut. Sevelamer is a hydrogel containing cross-linked polyallylamine chains. The negatively charged phosphate can be bound to the positively charged amine groups of the hydrogel in the intestines and removed via the faeces.

Sevelamer Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 26)Suppliers
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Jigs Chemical Limited +91 80 4290 2764 Ahmedabad, India 235 58 Inquiry
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GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49999 58 Inquiry
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Gihi Chemicals Co., Limited +86-0571-86217390 +8618058761490 China 998 58 Inquiry
Absin Bioscience Inc. 021-38015121 15000105423 China 24734 58 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 China 12308 58 Inquiry
MedChemExpress 021-58955995 United States 6398 58 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 China 29778 58 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Sevelamer 2-Propen-1-amine, polymer with (chloromethyl)oxirane Allylamine polymer with 1-chloro-2,3-epoxypropane Allylamine-epichlorohydrin copolymer Hsdb 7608 Oxirane, (chloromethyl)-, polymer with 2-propen-1-amine Sevelamer [inn:ban] Epichlorohydrin-PAA 25 copolymer 52757-95-6 C3H7NxC3H5ClOx