Sevelamer
Sevelamer
- CAS:
- 52757-95-6
- MF:
- C6H12ClNO
- MW:
- 149.62
Suppliers by country/region
Company Type
Properties
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
Safety Information
Use
In patients on dialysis, Sevelamer or lanthanum salts can be used to maintain normal phosphate blood levels. Sevelamer is a polymer containing amine groups. These protonated amine groups can react with the negatively charged phosphate groups via ionic binding and prevent absorption of phosphate from the gut. Sevelamer is a hydrogel containing cross-linked polyallylamine chains. The negatively charged phosphate can be bound to the positively charged amine groups of the hydrogel in the intestines and removed via the faeces.
1 India supplier list of "Sevelamer"