ARG-GLY-ASP-SER
![ARG-GLY-ASP-SER Structure](CAS/GIF/91037-65-9.gif)
- CAS No.
- 91037-65-9
- Chemical Name:
- ARG-GLY-ASP-SER
- Synonyms
- RGDS;RGDS peptide;ARG-GLY-ASP-SER;RGDS 1/2ACOH 2H2O;L-ARG-GLY-ASP-SER;Arg-Gly-Asp-Ser-OH;H-ARG-GLY-ASP-SER-OH;RGDS/ARG-GLY-ASP-SER;FIBRONECTIN INHIBITOR;Arg-Gly-Asp-Ser, >=98%
- CBNumber:
- CB9117206
- Molecular Formula:
- C15H27N7O8
- Molecular Weight:
- 433.42
- MOL File:
- 91037-65-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:39
Melting point | 183-187℃ |
---|---|
Density | 1.65±0.1 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | ≥21.65 mg/mL in H2O; insoluble in EtOH; insoluble in DMSO |
form | White to off-white powder |
pka | 2.84±0.10(Predicted) |
color | White to off-white |
Water Solubility | Soluble in water at 1mg/ml |
Sequence | H-Arg-Gly-Asp-Ser-OH |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
WGK Germany | 3 |
ARG-GLY-ASP-SER price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | A9041 | Arg-Gly-Asp-Ser ≥95% (HPLC) | 91037-65-9 | 2MG | ₹8151.23 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A9041 | Arg-Gly-Asp-Ser ≥95% (HPLC) | 91037-65-9 | 5MG | ₹14743.65 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A9041 | Arg-Gly-Asp-Ser ≥95% (HPLC) | 91037-65-9 | 10MG | ₹27019.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 03-34-0002 | H-Arg-Gly-Asp-Ser-OH - CAS 91037-65-9 - Calbiochem | 91037-65-9 | 25MG | ₹18980 | 2022-06-14 | Buy |
ARG-GLY-ASP-SER Chemical Properties,Uses,Production
Uses
Arg-Gly-Asp-Ser has been used:
- to study its effects on cell attachment in rats
- to analyse the interaction of fibrinogen with erythrocytes occurs through integrin related receptor
- to pretreat the cells, to assess the role of integrin in the cell attachment process
- to test its competition with platelet-secreted, nanosheet-adsorbed proteins for binding to glycoprotein IIIa (GPIIIa)
General Description
The tetrapeptide Arg-Gly-Asp-Ser (RGDS) is a key component of the cell attachment domain of fibronectin. The RGDS sequence was found initially to promote the attachment of rat kidney fibroblasts (NRKcells) to fibronectin and synthetic fibronectin peptides coupled to protein-coated plastic. Further investigation indicated that the free RGDS peptide inhibited the attachment of NRK cells to fibronectin coated substrates. The RGDS sequence has been shown to occur in several other proteins, such as the λ receptor on E. coli and the Sindbis coat protein. RGDS is also a target sequence for spirochete adherence of the syphilis bacterium Treponema pallidum.
RGDS has been shown to block fibrinogen-induced aggregation of intact erythrocytes and specific binding of fibrinogen to erythrocyte membranes. The effect of RGDS on transforming growth factor ?1 (TGF?1) mRNA expression and secretion in cultured human mesangial cells has been investigated. RGDS has been utilized in a study of integrin-mediated signal transduction in cultured cells from the sponge Suberites domuncula. RGDS has been demonstrated
to mitigate the binding of Mycobacterium tuberculosis to murine alveolar macrophages
ARG-GLY-ASP-SER Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 | China | 888 | 58 | Inquiry |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10260 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | China | 10297 | 58 | Inquiry |
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 6011 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
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