GLY-ARG-GLY-ASP-SER-PRO-LYS

GLY-ARG-GLY-ASP-SER-PRO-LYS Structure
CAS No.
111119-28-9
Chemical Name:
GLY-ARG-GLY-ASP-SER-PRO-LYS
Synonyms
GRGDSPK;EMD 56574;GRGDSPK (EMD 56574);GLY-ARG-GLY-ASP-SER-PRO-LYS;H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH;GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE;GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE;Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC);glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine;Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-lysine
CBNumber:
CB1123649
Molecular Formula:
C28H49N11O11
Molecular Weight:
715.76
MOL File:
111119-28-9.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:54:59

GLY-ARG-GLY-ASP-SER-PRO-LYS Properties

Density 1.59±0.1 g/cm3(Predicted)
storage temp. -20°C
pka 3.60±0.21(Predicted)
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

WGK Germany  3

GLY-ARG-GLY-ASP-SER-PRO-LYS price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) G1269 Gly-Arg-Gly-Asp-Ser-Pro-Lys ≥97% (HPLC) 111119-28-9 1MG ₹28058.4 2022-06-14 Buy
Product number Packaging Price Buy
G1269 1MG ₹28058.4 Buy

GLY-ARG-GLY-ASP-SER-PRO-LYS Chemical Properties,Uses,Production

Uses

Gly-Arg-Gly-Asp-Ser-Pro-Lys (RGD peptide) has been used-

  • as a blocking peptide to inhibit integrin-fibronectin binding
  • in adhesion assay performed on porcine trophectoderm to study the influence of TGFβ (transforming growth factor) on cell adhesion
  • for incubation of MC3T3-E1 osteoblast cells to determine its effect on cell adhesion measured by AFM (atomic force microscopy)
  • for the preparation of RGD.Flt23k.NR nanoparticles
  • to determine the involvement of RGD-integrin bonding in cell adhesion process

General Description

Gly-Arg-Gly-Asp-Ser-Pro-Lys is a RGD peptide. Naturally occurring RGD peptides, present in the ECM (extracellalar matrix) proteins, are involved in facilitating integrin-mediated cell adhesion to matrix proteins. RGD peptide is present as repeats in cell-adhesion protein, such as fibronectin and vitronectin. This tripeptide is recognized by cells by specific integrins (e.g. β1 , β3 , and β5 subunits), present on the cell surface and associated with the actin filament via the FA (focal adhesion)-complex.

Biochem/physiol Actions

Fibronectin analog that binds to integrins.

GLY-ARG-GLY-ASP-SER-PRO-LYS Preparation Products And Raw materials

Raw materials

Preparation Products

GLY-ARG-GLY-ASP-SER-PRO-LYS Suppliers

Global( 74)Suppliers
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Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
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Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
H-GLY-ARG-GLY-ASP-SER-PRO-LYS-OH GRGDSPK GRGDSPK, FIBRONECTIN ATTACHMENT PEPTIDE GLY-ARG-GLY-ASP-SER-PRO-LYS GLY-ARG-GLY-ASP-SER-PRO-LYS ACETATE glycyl- arginyl-glycyl-aspartyl-seryl-prolyl-lysine EMD 56574 L-Lysine, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl- Gly-Arg-Gly-Asp-Ser-Pro-Lys >=97% (HPLC) Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-lysine GRGDSPK (EMD 56574) 111119-28-9 C28H49N11O11 Extracellular Matrix Extracellular Matrix Peptides and Proteins Cytoskeleton and Extracellular Matrix Cell Signaling and Neuroscience BioChemical Cell Biology peptide