Flibanserin
- CAS No.
- 167933-07-5
- Chemical Name:
- Flibanserin
- Synonyms
- Filbanserin;Flibanserine;BIMT;Niemunerkeine;1,3-Dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one;Girosa;Bimt 17;BIMT 17BS;Fbanselin;Flibanerins
- CBNumber:
- CB91178756
- Molecular Formula:
- C20H21F3N4O
- Molecular Weight:
- 390.4
- MOL File:
- 167933-07-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/9/25 14:54:50
Density | 1.292±0.06 g/cm3(Predicted) |
---|---|
storage temp. | 2-8°C |
solubility | DMSO: soluble10mg/mL, clear |
form | powder |
pka | 12.12±0.30(Predicted) |
color | white to beige |
InChI | InChI=1S/C20H21F3N4O/c21-20(22,23)15-4-3-5-16(14-15)26-11-8-25(9-12-26)10-13-27-18-7-2-1-6-17(18)24-19(27)28/h1-7,14H,8-13H2,(H,24,28) |
InChIKey | PPRRDFIXUUSXRA-UHFFFAOYSA-N |
SMILES | C1(=O)N(CCN2CCN(C3=CC=CC(C(F)(F)F)=C3)CC2)C2=CC=CC=C2N1 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
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Signal word | Danger | |||||||||
Hazard statements | H301-H315-H319-H335 | |||||||||
Precautionary statements | P301+P310+P330-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | T | |||||||||
Risk Statements | 25-36/37/38 | |||||||||
Safety Statements | 26-45 | |||||||||
RIDADR | UN 2811 6.1 / PGIII | |||||||||
WGK Germany | 3 | |||||||||
NFPA 704 |
|
Flibanserin price More Price(2)
Flibanserin Chemical Properties,Uses,Production
Description
Flibanserin is a drug originally developed by Boehringer-Ingelheim and later Sprout Pharmaceuticals, which was approved in 2015 by the FDA for the treatment of premenopausal women with hypoactive sexual desire disorder (HSDD). The drug, which was originally developed for the treatment of depression by Boehringer- Ingelheim, is a full agonist of the 5-HT1A receptor, an antagonist of the 5-HT2A receptor, and a partial agonist of the dopamine-4 (D4) receptor, which triggers increased dopamine and norepinephrine levels along with decreased serotonin levels. In three randomized trials involving 2400 premenopausal women, the drug was found to increase the number of satisfying sexual events by 0.5-1.0 events per month and increased sexual desire on average by 10-12% over placebo. Side effects include decreased blood pressure and loss of consciousness, especially in subjects who consumed alcohol.
Uses
Antidepressant (5-HT1a agonist and 5-HT2 antagonist).
Flibanserin Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Viyash Life Sciences Pvt Ltd | +91-4023635052 +91-4023635052 | Telangana, India | 213 | 58 | Inquiry |
Apicore Pharmaceuticals Pvt Ltd | +91-2662267177 +91-2662267166 | Gujarat, India | 181 | 58 | Inquiry |
Century Pharmaceuticals Ltd | +91-2652361581 +91-2652361581 | Gujarat, India | 53 | 58 | Inquiry |
Symed Laboratories Ltd | +91-9505426644 +91-9505426644 | Telangana, India | 54 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
IHR Polytech LLP | 08046070046 | Ahmedabad, India | 3 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
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