Ristocetin

Ristocetin Structure
CAS No.
11021-66-2
Chemical Name:
Ristocetin
Synonyms
Ristomycin A;Ristocetin, RistoMycin III, Spontin, Riston
CBNumber:
CB91179667
Molecular Formula:
C95H110N8O44
Molecular Weight:
2067.92
MOL File:
11021-66-2.mol
Modify Date:
2023/4/20 16:15:45

Ristocetin Properties

alpha D -120 to -133° (water)
Density 1.76±0.1 g/cm3(Predicted)
pka 8.55±0.70(Predicted)

SAFETY

Risk and Safety Statements

RIDADR  3249
HazardClass  6.1(b)
PackingGroup  III
Toxicity mouse,LD50,intravenous,1350mg/kg (1350mg/kg),SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE,"Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967Vol. -, Pg. 568, 1967.

Ristocetin Chemical Properties,Uses,Production

Uses

Ristocetin A sulfate is a potent antibacterial glycopeptide antibiotic that was withdrawn from clinical use following a high incidence of thrombocytopenia. Further investigation found that ristocetin A induced platelet aggregation by binding to a factor absent in people suffering from von Willebrand's disease, leading to the use of ristocetin A as an important diagnostic aid.

Ristocetin Preparation Products And Raw materials

Raw materials

Preparation Products

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Ristomycin A Ristocetin, RistoMycin III, Spontin, Riston 11021-66-2