ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Chloropyrimidine >4-Chloro-2,6-diaminopyrimidine

4-Chloro-2,6-diaminopyrimidine

CAS No.: 156-83-2

Chemical Name:: 4-Chloro-2,6-diaminopyrimidine

Synonyms: 2,4-DIAMINO-6-CHLOROPYRIMIDINE;6-CHLORO-PYRIMIDINE-2,4-DIAMINE;NSC 8818;JACS-156-83-2;TIMTEC-BB SBB004123;4-Chloro-2,6-diamino;DiaMino-6-chloropyriMid;Minoxidil EP Impurity B;Minoxidil EP Impurity 3;oro-2,6-diaminopyrimidine

CBNumber:: CB9194300

Molecular Formula:: C4H5ClN4

Molecular Weight:: 144.56

MOL File:: 156-83-2.mol

MSDS File:: SDS

Modify Date:: 2024/8/1 13:52:05

Request For Quotation

4-Chloro-2,6-diaminopyrimidine Properties

Melting point	199-202 °C(lit.)
Boiling point	199-202 °C
Density	1.3966 (rough estimate)
vapor pressure	0.0±1.1 mmHg at 25°C
refractive index	1.702
Flash point	218.9±29.6 °C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	slightly soluble
pka	3.66±0.10(Predicted)
form	Solid
color	White to Pale Yellow
Water Solubility	slightly soluble
BRN	118455
InChI	InChI=1S/C4H5ClN4/c5-2-1-3(6)9-4(7)8-2/h1H,(H4,6,7,8,9)
InChIKey	QJIUMVUZDYPQRT-UHFFFAOYSA-N
SMILES	C1(N)=NC(Cl)=CC(N)=N1
CAS DataBase Reference	156-83-2(CAS DataBase Reference)
NIST Chemistry Reference	Pyrimidine, 6-chloro-2,4-diamino-(156-83-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Xn,Xi

Risk Statements

22-36/37/38

Safety Statements

26-24/25

WGK Germany

Hazard Note

Irritant

HS Code

29335995

NFPA 704

	1
2		0

4-Chloro-2,6-diaminopyrimidine price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	C33204	2,6-Diamino-4-chloropyrimidine 98%	156-83-2	5G	₹2933.58	2022-06-14	Buy
Sigma-Aldrich(India)	C33204	2,6-Diamino-4-chloropyrimidine 98%	156-83-2	25G	₹7339.35	2022-06-14	Buy
TCI Chemicals (India)	C0811	6-Chloro-2,4-diaminopyrimidine min. 98.0 %	156-83-2	25G	₹5300	2022-05-26	Buy

Product number	Packaging	Price	Buy
C33204	5G	₹2933.58	Buy
C33204	25G	₹7339.35	Buy
C0811	25G	₹5300	Buy

4-Chloro-2,6-diaminopyrimidine Chemical Properties,Uses,Production

Chemical Properties

White Cyrstalline Solid

Uses

Definition

ChEBI: 6-chloro-2,4-pyrimidinediamine (4-Chloro-2,6-diaminopyrimidine) is a member of pyrimidines and an organohalogen compound.

Synthesis

2,4-Diamino-6-hydroxypyrimidine (1.00 g, 7.93 mmol) was added to POCl3 (9 mL) and stirred at 97 ℃ for 17 h. The reaction solution was added to ice water slowly and then stirred at 90 C for 1 h. The pH of this solution was adjusted to 8 with NaOH, and then it was extracted with EtOAC (150 mL 3). The combined organic layers were dried with Na2SO4, filtered, and concentrated to give white solid 4-Chloro-2,6-diaminopyrimidine 0.97 g, yielding 85%.

Purification Methods

It recrystallises from boiling H2O (charcoal) as needles; it also crystallises from Me2CO. [Büttner Chem Ber 36 2232 1903, Roth J Am Chem Soc 72 1914 1950, UV: Brown & Jacobsen J Chem Soc 3172 1962, Beilstein 24 H 318, 25 III/IV 2788.]

4-Chloro-2,6-diaminopyrimidine Preparation Products And Raw materials

Raw materials

Phosphorus oxychloride Sodium Methoxide Guanidine nitrate Methyl cyanoacetate

Preparation Products

2,4-DIAMINO-6-ETHOXYPYRIMIDINE 2,4-DIAMINO-6-PIPERIDINOPYRIMIDINE 5-bromo-6-chloropyrimidine-2,4-diamine 6-CHLORO-5-NITROPYRIMIDINE-2,4-DIAMINE

4-Chloro-2,6-diaminopyrimidine Suppliers

Global( 625)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Synthetic Research Pharma Laboratories Pvt Ltd	+91 9848023377	Hyderabad, India	116	58	Inquiry
Saflik Pharma	+91 7600062602	Gujarat, India	25	58	Inquiry
SVH BIOSCIENCES	+91-6303499280 +91-6303499280	Hyderabad, India	478	58	Inquiry
SSM LABS	+91-7386809859 +91-9963470802	Telangana, India	15	58	Inquiry
JIVICHEM SYNTHESIS PVT LTD	+91-7028392790 +91-7028392790	Maharashtra, India	337	58	Inquiry
Symphony Pharma Life Sciences	+91-9550352323 +91-9550352323	Telangana, India	7	58	Inquiry
Louis Pharmaceuticals Pvt Ltd	+91-8498087900 +91-8498087900	Telangana, India	23	58	Inquiry
Sonia Organics	+91-9538454135 +91-9538454135	Karnataka, India	28	58	Inquiry
Credas Labs Pvt Ltd	+91 9133918031	Hyderabad, India	119	58	Inquiry
SNECOFRi Pvt Ltd	+91-9032850129 +91-9032850129	Telangana, India	404	58	Inquiry

Supplier	Advantage
Synthetic Research Pharma Laboratories Pvt Ltd	58
Saflik Pharma	58
SVH BIOSCIENCES	58
SSM LABS	58
JIVICHEM SYNTHESIS PVT LTD	58
Symphony Pharma Life Sciences	58
Louis Pharmaceuticals Pvt Ltd	58
Sonia Organics	58
Credas Labs Pvt Ltd	58
SNECOFRi Pvt Ltd	58

4-Chloro-2,6-diaminopyrimidine: properties, applications and safety
4-Chloro-2,6-diaminopyrimidine is a white crystalline solid with potential environmental applications and associated safety ri....
Oct 12，2023

What is 4-Chloro-2,6-diaminopyrimidine?
4-Chloro-2,6-diaminopyrimidine(DACP) is a member of pyrimidines and an organohalogen compound. It is a white crystal-like soli....
Jan 16，2020

4-Chloro-2,6-diaminopyrimidine Spectrum

4-Chloro-2,6-diaminopyrimidine(156-83-2)MS 4-Chloro-2,6-diaminopyrimidine(156-83-2)¹HNMR 4-Chloro-2,6-diaminopyrimidine(156-83-2)¹³CNMR 4-Chloro-2,6-diaminopyrimidine(156-83-2)IR1 4-Chloro-2,6-diaminopyrimidine(156-83-2)IR2 4-Chloro-2,6-diaminopyrimidine(156-83-2)Raman

156-83-2(4-Chloro-2,6-diaminopyrimidine)Related Search:

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4-Chloro-2,6-Diaminopyrimidine-N-Oxide,6-Chloro-2,4-diaminopyrimidine-N-oxide 4-CHLORO-6-MORPHOLIN-4-YLPYRIMIDIN-2-AMINE 6-CHLORO-N4,N4-DIETHYLPYRIMIDINE-2,4-DIAMINE 4-CHLORO-5,6-DIAMINOPYRIMIDINE,6-Chloro-4,5-diaminopyrimidine 2-CHLORO-4,5-DIAMINOPYRIMIDINE

4-Chloropyrimidine Minoxidil 6-CHLORO-N4,N4-DIPROPYL-2,4-PYRIMIDINEDIAMINE

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4-DiaMino-6-chloropyriMidine NSC 8818 DIAMINO-6-CHLOROPYRIMIDINE, 2,4-(SH) 2,4-DIAMINO-6-CHLOROPYRIMIDINE FOR SYNTH 2,6-DiaMino-4-chloropyriMidine 98% DiaMino-6-chloropyriMid 2,4-Diamino-6-chloropyrimidine,98% 4-Chloro-2,6-diaminopyrimidine, 4-Chloro-2,6-diamino-1,3-diazine 2,4-Diamino-6-chloropyrimidine for synthesis 2-AMINO-6-CHLORO-4-PYRIMIDINYLAMINE Pyrimidine,2,4-diamino-6-chloro- 2,4-Diamino-6-Chloro Pyridine 2,6-DIAMINO-4-CHLORO PYRIMIDINE 4-Chloro-2-6-Diaminopyrimide 2,4-Diamino-6-chloropyrimidine, 99+% 2,4-Pyrimidinediamine, 6-chloro- (9CI) 6-Chloro-pyrimidine-2,4-diyldiamine, 4-Chloro-2,6-diaminopyrimidine 2,4-DIAMINO-6-CHLOROPYRIMIDINE/ MINOXIDIL 4-CHLORO-2,6-DIAMINOPYRIMIDINE 98% 4-CHLORO-2,6-DIAMINOPYRIMIDINE (2,4-DIAMINO-6-CHLOROPYRIMIDINE) 4-Chloropyrimidine-2,6-diamine 4-Chloro-2,6-diaminopyrimidine,98% 4-Chloro-2,6-diaminopyrimidine ,99% 2,6-Diamino-4-chloropyrimidine,4-Chloro-2,6-diaminopyrimidine 4-Chloro-2,6-diamino 2,6-Diamino-4-chloropyrimidine ,98% 2,6-Diamino-4-chloropyrimidine (Internal Standard) 4-CHLORO-2,6-DIAMINOPYRIMIDINE 6-CHLORO-PYRIMIDINE-2,4-DIYLDIAMINE 6-CHLORO-2,4-DIAMINOPYRIMIDINE TIMTEC-BB SBB004123 2,4-Pyrimidinediamine, 6-chloro- 2,4-Pyrimidinediamine,6-chloro- 4-Chloro-2,6-pyrimidinediamine 6-Chlor-2,4-diaminopyrimidin(4-2,6) 6-Chloro-2,4-pyrimidinediamine 6-chloro-4-pyrimidinediamine 156-83-2, MFCD00006097, 4-Chloro-2,6-diaminopyrimidine JACS-156-83-2 Minoxidil EP Impurity B 2,6-Diamini-4-chloro pyrimidine 2,4-Diamino-6-chloropyramidine Minoxidil Impurity 2(Minoxidil EP Impurity B） 6-Chloro-2,4-diaminopyrimidine > 2,6-Diamino-4-chloropyrimidine (Internal Standard)@1000 μg/mL in Pyridine 156-83-2, MFCD00006097, 4-ChL oro-2,6-diaminopyrimidine 2,4-DIAMINO-6-CHLOROPYRIMIDINE 6-CHLORO-PYRIMIDINE-2,4-DIAMINE 2,4-Diamino-6-chloropyrimidine (2,4-DACP) Minoxidil EP Impurity 3 DIAMINO-6-CHLOROPYRIMIDINE, 2,4- 156-83-2 C4H5CIN4 HETERO CHLORIDE Pyrimidines Heterocyclic Building Blocks Halogenated Heterocycles