5-Hydroxyindole-2-carboxylic acid

5-Hydroxyindole-2-carboxylic acid Structure
CAS No.
21598-06-1
Chemical Name:
5-Hydroxyindole-2-carboxylic acid
Synonyms
5-HO-ICA;NSC 117338;5-HYDROXY-2-INDOLECARBOXYLIC ACID;5-HYDROXYINDOLE-2-CARBOXYLIC ACID;5-Hydroxyindole-2-carboxylicacid,97%;5-Hydroxy-2-indolecarboxylic acid 98%;5-HYDROXY-1H-INDOLE-2-CARBOXYLIC ACID;5-Hydroxyindole-2-carboxylic acid 98%;5-Hydroxy-2-indolecarboxylic acid,98%;1H-Indole-2-carboxylic acid, 5-hydroxy-
CBNumber:
CB9206982
Molecular Formula:
C9H7NO3
Molecular Weight:
177.16
MOL File:
21598-06-1.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:35

5-Hydroxyindole-2-carboxylic acid Properties

Melting point 249 °C (dec.) (lit.)
Boiling point 309.06°C (rough estimate)
Density 1.3312 (rough estimate)
refractive index 1.5200 (estimate)
storage temp. Sealed in dry,2-8°C
solubility chloroform/ethanol (1:1): soluble50mg/mL, clear to slightly hazy, yellow to brown
pka 4.38±0.30(Predicted)
form Fuming Liquid
color Clear colorless to slightly yellow
BRN 153214
CAS DataBase Reference 21598-06-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-21/22
Safety Statements  26-36-36/37/39
WGK Germany  3
HS Code  29339900
NFPA 704
1
2 1

5-Hydroxyindole-2-carboxylic acid price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 143510 5-Hydroxyindole-2-carboxylic acid ≥96.5% 21598-06-1 1G ₹5791.38 2022-06-14 Buy
Sigma-Aldrich(India) 143510 5-Hydroxyindole-2-carboxylic acid ≥96.5% 21598-06-1 1G ₹5791.38 2022-06-14 Buy
Sigma-Aldrich 143510 5-Hydroxyindole-2-carboxylic acid ≥96.5% 21598-06-1 5G ₹21888.15 2022-06-14 Buy
Sigma-Aldrich(India) 143510 5-Hydroxyindole-2-carboxylic acid ≥96.5% 21598-06-1 5G ₹21888.15 2022-06-14 Buy
Product number Packaging Price Buy
143510 1G ₹5791.38 Buy
143510 1G ₹5791.38 Buy
143510 5G ₹21888.15 Buy
143510 5G ₹21888.15 Buy

5-Hydroxyindole-2-carboxylic acid Chemical Properties,Uses,Production

Chemical Properties

light yellow to beige crystalline powder

Uses

• ;Reactant for preparation of indole C5-O-substituted seco-cyclopropylindole analogs as potential anticancer agents• ;Reactant for microwave combinatorial synthesis of indolic arylpiperazine derivatives as ligands for 5-HT1A, 5-HT2A, and 5-HT2C receptors1• ;Reactant for preparation of melanins as novel nature-inspired radioprotectors2• ;Reactant for preparation of 5-Hydroxyindole-2-carboxylic acid amides as histamine-3 receptor inverse agonists for the treatment of obesity3• ;Reactant for preparation of conformationally constrained peptidomimetic inhibitors of signal

General Description

5-Hydroxyindole-2-carboxylic acid on oxidation with KMnO4 yields pyrrole-2,3,5-tricarboxylic acid.

5-Hydroxyindole-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-HYDROXYINDOLE-2-CARBOXYLIC ACID 5-HYDROXY-1H-INDOLE-2-CARBOXYLIC ACID 5-HYDROXY-2-INDOLECARBOXYLIC ACID 5-HO-ICA 5-Hydroxyindole-2-carboxylicacid,97% 5-Hydroxy-2-indolecarboxylic acid, 98% 1GR NSC 117338 5-Hydroxy-2-indolecarboxylic acid 98% 5-HYDROXYINDOLE-2-CARBOXYLIC ACID(5OHI2CA) 5-Hydroxy-2-indolecarboxylic acid,98% 5-Hydroxyindole-2-carboxylic acid 98% 1H-Indole-2-carboxylic acid, 5-hydroxy- 21598-06-1 C9H7NO3 Building Blocks Heterocyclic Building Blocks Indoles Building Blocks Heterocyclic Building Blocks Building Blocks C7 to C9 Chemical Synthesis Heterocyclic Building Blocks Indoles Heterocyclic Compounds Indoles and derivatives Indole Organic acids