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ChemicalBook > Product Catalog >Organic Chemistry >Nitrogen Compounds >6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone

6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone

6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone Structure
CAS No.
328956-08-7
Chemical Name:
6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone
Synonyms
6-Fluoro-4-(trifluoromethyl)quinolin-2-ol;6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone;6-fluoro-4-(trifluoromethyl)-1H-quinolin-2-one;6-Fluoro-4-(trifluoroMethyl)quinolin-2(1H)-one;6-Fluoro-4-(trifluoromethyl)quinolin-2-ol ,97%;2(1H)-Quinolinone, 6-fluoro-4-(trifluoromethyl)-;6-Fluoro-2-hydroxy-4-(trifluoroMethyl)quinoline, 97%
CBNumber:
CB92128695
Molecular Formula:
C10H5F4NO
Molecular Weight:
231.15
MOL File:
328956-08-7.mol
Modify Date:
2024/1/19 11:51:18
Request For Quotation

6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone Properties

Melting point 252-253 °C (decomp)(Solv: ethanol (64-17-5))
Boiling point 282 ºC
Density 1.468
Flash point 124 ºC
storage temp. 2-8°C
pka 9.33±0.70(Predicted)
InChI InChI=1S/C10H5F4NO/c11-5-1-2-8-6(3-5)7(10(12,13)14)4-9(16)15-8/h1-4H,(H,15,16)
InChIKey WUFRBOSKPZUGIS-UHFFFAOYSA-N
SMILES N1C2=C(C=C(F)C=C2)C(C(F)(F)F)=CC1=O

SAFETY

Risk and Safety Statements

Risk Statements  36/37/38
Safety Statements  26-36/37/39
HS Code  29334900

6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone Chemical Properties,Uses,Production

Chemical Properties

White solid

Description

As a quinoline derivative, 6-Fluoro-4-hydroxy-2-(trifluoromethyl)quinoline is substituted with trifluoromethyl, hydroxyl, and fluoride groups. In particular, 6-Fluoro-4-hydroxy-2-(trifluoromethyl)quinoline can exist in a tautomeric form, known as quinolone, where the hydroxy group becomes a ketone and the imine changes to an amine. This compound is a precursor for synthesizing thioquinolines, which are used to develop non-cytotoxic, potent and selective antitubercular agents. The thiolation reaction is carried out using phosphorus pentasulfide in pyridine.

6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone Preparation Products And Raw materials

Raw materials

Ethyl 4,4,4-trifluoroacetoacetate 4-Fluoroaniline Sulfuric acid

Preparation Products

2-Bromo-6-fluoro-4-(trifluoromethyl)quinoline

6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone Suppliers

Global( 56)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Hongxiong +undefined18915499068 China 120 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29897 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Neostar United (Changzhou) Industrial Co., Ltd. +86-519-519-85557386 China 11973 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
Hunan Jibang Biological Technology Co., LTD +8613776644403 China 1806 58 Inquiry
Aceschem Inc. +1-817863-6948 +1-（817）863-6948 United States 19639 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Supplier Advantage
A.J Chemicals 58
Hongxiong 58
career henan chemical co 58
Chongqing Chemdad Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58
Neostar United (Changzhou) Industrial Co., Ltd. 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
Hunan Jibang Biological Technology Co., LTD 58
Aceschem Inc. 58
Aladdin Scientific 58

328956-08-7(6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone)Related Search:

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6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone
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6-Fluoro-4-(trifluoromethyl)-2(1H)-quinolinone 6-Fluoro-4-(trifluoromethyl)quinolin-2-ol 6-Fluoro-4-(trifluoromethyl)quinolin-2-ol ,97% 6-Fluoro-2-hydroxy-4-(trifluoroMethyl)quinoline, 97% 6-Fluoro-4-(trifluoroMethyl)quinolin-2(1H)-one 6-fluoro-4-(trifluoromethyl)-1H-quinolin-2-one 2(1H)-Quinolinone, 6-fluoro-4-(trifluoromethyl)- 328956-08-7