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Ipratropium bromide monohydrate

Ipratropium bromide monohydrate Structure
CAS No.
66985-17-9
Chemical Name:
Ipratropium bromide monohydrate
Synonyms
IPRATROPIUM BROMIDE;pratropium Bromide;Unii-J697uz2A9j;Ipratropium Bromider;Ipratropium bromide CRS;Ipratropium Bromide (100 mg);Ipratropium bromide 1-hydrate;Ipratropium Bromide (1347507);Ipratropium Bromide (I0360000);Iptratropium Bromide Anhydrous
CBNumber:
CB92130854
Molecular Formula:
C20H32BrNO4
Molecular Weight:
430.38
MOL File:
66985-17-9.mol
Modify Date:
2023/11/20 12:07:38

Ipratropium bromide monohydrate Properties

Melting point 231 °C
storage temp. 2-8°C
solubility H2O: soluble10mg/mL
form powder
color white
Stability Hygroscopic
InChIKey KEWHKYJURDBRMN-XSAPEOHZNA-M
SMILES C([N+]1([C@@H]2C[C@@H](OC(=O)C(C3C=CC=CC=3)CO)C[C@H]1CC2)C)(C)C.[Br-].O |&1:2,4,18,r|

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H332-H319
Precautionary statements  P261-P264-P270-P301+P312-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn
Risk Statements  20/22-36
Safety Statements  26
RTECS  YM3700000
HS Code  2939800000
NFPA 704
0
1 0

Ipratropium bromide monohydrate price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) I1637 Ipratropium bromide monohydrate ≥98% (TLC), powder 66985-17-9 250MG ₹12567.83 2022-06-14 Buy
Sigma-Aldrich(India) I1637 Ipratropium bromide monohydrate ≥98% (TLC), powder 66985-17-9 1G ₹34661.65 2022-06-14 Buy
TCI Chemicals (India) I0907 Ipratropium Bromide Monohydrate 66985-17-9 200MG ₹6200 2022-05-26 Buy
TCI Chemicals (India) I0907 Ipratropium Bromide Monohydrate 66985-17-9 1G ₹14800 2022-05-26 Buy
Product number Packaging Price Buy
I1637 250MG ₹12567.83 Buy
I1637 1G ₹34661.65 Buy
I0907 200MG ₹6200 Buy
I0907 1G ₹14800 Buy

Ipratropium bromide monohydrate Chemical Properties,Uses,Production

Description

Ipratropium bromide is a quaternary ammonium congener of atropine and is an anticholinergic compound approved for use as a bronchodilator. Anticholinergic agents produce bronchodilatation by antagonizing the activity of acetylcholine at the level of its receptor, particularly those found on airway smooth muscle in the large, central airways. The onset of action of ipratropium is relatively slow (20 minutes), and the peak effect occurs at 60 minutes.1 Ipratropium, unlike atropine, is poorly absorbed across mucous membranes and has little toxicity at the usual doses.

Chemical Properties

White or almost white, crystalline powder.

Uses

Ipratropium bromide monohydrate has been used for the inhibition of peripheral muscarinic receptors in rats.

Definition

ChEBI: The monohydrate form of ipratropium bromide. An anticholinergic drug, ipratropium bromide blocks the muscarinic cholinergic receptors in the smooth muscles of the bronchi in the lungs. This opens the bronchi, so providing relief in chronic obstructive pulm nary disease and acute asthma.

Side effects

Previous severe allergic reaction symptoms upon using ipratropium or atropine and its other derivatives, such as angioedema, urticaria, severe shortness of breath, oropharyngeal edema, and ultimately anaphylaxis is a contraindication to ipratropium use.
Ipratropium aerosols can cause bronchospasms (paradoxical), which usually happens upon the initial use of this medication

Ipratropium bromide monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 198)Suppliers
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Micro Orgo Chem +91-91-022-24969510 +91-9082984052 Mumbai, India 66 58 Inquiry
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Innovative Synthetic Molecules +91 40-24111684 Hyderabad, India 527 58 Inquiry

Ipratropium bromide monohydrate Spectrum

Unii-J697uz2A9j Ipratropium Bromide (100 mg) 3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo(3.2.1)octane bromide monohydrate 8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl IPRATROPIUM BROMIDE MONOHYDRATE Ipratropium bromide CRS IpratropiumBromideMonohydrate> Ipratropium Bromider Ipratropium bromide 1-hydrate Ipratropium Bromide (I0360000) Ipratropium Bromide (1347507) IPRATROPIUM BROMIDE pratropium Bromide 13C,2H3]-Ipratropium bromide salt Iptratropium Bromide Anhydrous 66985-17-9 C20H30NO3H2OBr VASOTEC