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LINDERANE

CAS No.: 13476-25-0

Chemical Name:: LINDERANE

Synonyms: linerane;LINDERANE;Linderane-RM;LINDERANE(RG);wuyaomineizhi;Linderane ,98%;Linderane, 98%, from Lindera aggregata (Sims) Kosterm.;(1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-2H-10,1a-(epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one;(1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-10,1a-(epoxymethano)-2H-oxireno[4,5]cyclodeca[1,2-b]furan-12-one;2H-10,1a-(Epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one,3,6,10,10a-tetrahydro-5,9-dimethyl-, (1aS,4E,10S,10aS)-

CBNumber:: CB9243408

Molecular Formula:: C15H16O4

Molecular Weight:: 260.29

MOL File:: 13476-25-0.mol

MSDS File:: SDS

Modify Date:: 2025/4/17 18:22:24

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LINDERANE Properties

Melting point	190～191℃
Boiling point	434.5±45.0 °C(Predicted)
Density	1.30±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
Stability	Hygroscopic

SAFETY

Risk and Safety Statements

Safety Statements	24/25
HS Code	29322090

LINDERANE Chemical Properties,Uses,Production

Description

Linderane is a sesquiterpene that has been found in L. aggregata. It inhibits the cytochrome P450 (CYP) isoform CYP2C9 (K_i = 1.26 μM) in an irreversible and NADPH-dependent manner. Linderane decreases phosphoenolpyruvate carboxykinase (Pck1) and glucose-6-phosphatase (G6pc) gene expression, cAMP concentration, and CREB phosphorylation, increases phosphodiesterase 3 (PDE3) activity, and inhibits gluconeogenesis in rat primary hepatocytes. In vivo, linderane (50 mg/kg twice per day) decreases serum and hepatic triglyceride levels, as well as random-fed and fasting blood glucose levels in ob/ob mice.

Uses

Linderane is a sequiterpene lactone extract from Lindera strychnifolia compound used as a cytotoxic agent against hepaic stellate cells.

LINDERANE Preparation Products And Raw materials

Raw materials

Preparation Products

LINDERANE Suppliers

Global( 199)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21628	55	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29858	58	Inquiry
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	China	3772	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	32159	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	China	34563	58	Inquiry
Apeloa Pharmaceutical Co., Ltd.	+86-0571-87635730 +8615858229168	China	1478	58	Inquiry
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	China	23541	58	Inquiry
Hebei baicao biology science and technology co., ltd	+86-19131911055 +8617824879454	China	1029	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24727	58	Inquiry
TargetMol Chemicals Inc.		United States	38630	58	Inquiry

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Chengdu Biopurify Phytochemicals Ltd.	58
TargetMol Chemicals Inc.	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Apeloa Pharmaceutical Co., Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58
Hebei baicao biology science and technology co., ltd	58
LEAP CHEM CO., LTD.	58
TargetMol Chemicals Inc.	58

LINDERANE Spectrum

LINDERANE(13476-25-0)¹³CNMR

13476-25-0(LINDERANE)Related Search:

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6-(2-O-alpha-L-Arabinopyranosyl-beta-D-glucopyranosyl)-2-[4-(beta-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one Rutaecarpine schisanhenol LAUROLITSINE HEXABROMOBENZENE

1,4-Dioxan-2-one LINDERANE 3,4-Epoxytetrahydrofuran

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LINDERANE 2H-10,1a-(Epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one,3,6,10,10a-tetrahydro-5,9-dimethyl-, (1aS,4E,10S,10aS)- (1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-10,1a-(epoxymethano)-2H-oxireno[4,5]cyclodeca[1,2-b]furan-12-one (1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-2H-10,1a-(epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one LINDERANE(RG) Linderane ,98% Linderane, 98%, from Lindera aggregata (Sims) Kosterm. wuyaomineizhi linerane Linderane-RM 13476-25-0 phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract chemical reagent pharmaceutical intermediate