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(4Z)-7-[(1R,2R,3S,5S)-5-([1,1'-BIPHENYL]-4-YLMETHOXY)-3-HYDROXY-2-(1-PIPERIDINYL)CYCLOPENTYL]-4-HEPTENOIC ACID HYDROCHLORIDE

(4Z)-7-[(1R,2R,3S,5S)-5-([1,1'-BIPHENYL]-4-YLMETHOXY)-3-HYDROXY-2-(1-PIPERIDINYL)CYCLOPENTYL]-4-HEPTENOIC ACID HYDROCHLORIDE Structure
CAS No.
85505-64-2
Chemical Name:
(4Z)-7-[(1R,2R,3S,5S)-5-([1,1'-BIPHENYL]-4-YLMETHOXY)-3-HYDROXY-2-(1-PIPERIDINYL)CYCLOPENTYL]-4-HEPTENOIC ACID HYDROCHLORIDE
Synonyms
SN-309;GR-32191;GR 32191B;Vapiprost;GR32191HCl;Vapiprostum;Unii-H84xt1coau;Vapiprost [inn:ban];Vapiprostum [latin];GR 32191 HYDROCHLORIDE
CBNumber:
CB9244849
Molecular Formula:
C30H39NO4
Molecular Weight:
477.64
MOL File:
85505-64-2.mol
Modify Date:
2023/7/12 17:17:57
Request For Quotation

(4Z)-7-[(1R,2R,3S,5S)-5-([1,1'-BIPHENYL]-4-YLMETHOXY)-3-HYDROXY-2-(1-PIPERIDINYL)CYCLOPENTYL]-4-HEPTENOIC ACID HYDROCHLORIDE Properties

Melting point 127-128 °C
Boiling point 649.3±55.0 °C(Predicted)
Density 1.18±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility H2O: ~16 mg/mL
form solid
pka 4.61±0.10(Predicted)
color off-white

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

(4Z)-7-[(1R,2R,3S,5S)-5-([1,1'-BIPHENYL]-4-YLMETHOXY)-3-HYDROXY-2-(1-PIPERIDINYL)CYCLOPENTYL]-4-HEPTENOIC ACID HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

Antagonist (thromboxane A2).

Biological Activity

Potent thromboxane A 2 (TP) receptor antagonist. Inhibits platelet aggregation (pA 2 ~ 8.3) and relaxes vascular and airway smooth muscle (pA 2 = 7.9-10.3).

(4Z)-7-[(1R,2R,3S,5S)-5-([1,1'-BIPHENYL]-4-YLMETHOXY)-3-HYDROXY-2-(1-PIPERIDINYL)CYCLOPENTYL]-4-HEPTENOIC ACID HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Pyridine sulfur trioxide Triethylamine Peroxyacetic acid Diisobutylaluminium hydride (Methoxymethyl)triphenylphosphonium chloride
Benzyltriethylammonium chloride (3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE Potassium tert-butoxide 1-(3-BIPHENYLYL)PIPERAZINE
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Preparation Products

(4Z)-7-[(1R,2R,3S,5S)-5-([1,1'-BIPHENYL]-4-YLMETHOXY)-3-HYDROXY-2-(1-PIPERIDINYL)CYCLOPENTYL]-4-HEPTENOIC ACID HYDROCHLORIDE Suppliers

Global( 14)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24017 58 Inquiry
Tocris Bioscience +44 (0) 117 916 3333 United Kingdom 5729 77 Inquiry
SIGMA-RBI 800 736 3690 (Orders) Switzerland 6913 91 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 China 15848 69 Inquiry
Supplier Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Pharma Affiliates 58
TargetMol Chemicals Inc. 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
TargetMol Chemicals Inc. 58
Tocris Bioscience 77
SIGMA-RBI 91
Service Chemical Inc. 71
Lanospharma Laboratories Co.,Ltd 56
3B Pharmachem (Wuhan) International Co.,Ltd. 69

85505-64-2((4Z)-7-[(1R,2R,3S,5S)-5-([1,1'-BIPHENYL]-4-YLMETHOXY)-3-HYDROXY-2-(1-PIPERIDINYL)CYCLOPENTYL]-4-HEPTENOIC ACID HYDROCHLORIDE)Related Search:

CIS-2-AMINO-CYCLOPENTANOL HYDROCHLORIDE Cyclopentanol,2-amino-,(1R,2S)-rel-(9CI) (4Z)-7-[(1R,2R,3S,5S)-5-([1,1'-BIPHENYL]-4-YLMETHOXY)-3-HYDROXY-2-(1-PIPERIDINYL)CYCLOPENTYL]-4-HEPTENOIC ACID HYDROCHLORIDE cis-(1S,2R)-2-Aminocyclopentanol hydrochloride
(4Z)-7-((1R,2R,3S,5S)-5-((1,1'-Biphenyl)-4-ylmethoxy)-3-hydroxy-2-(1-piperidinyl)cyclopentyl)-4-heptenoicacid GR32191HCl (Z)-7-[(1R)-5α-[(1,1'-Biphenyl-4-yl)methoxy]-3β-hydroxy-2β-(piperidin-1-yl)cyclopentan-1α-yl]-4-heptenoic acid GR-32191 SN-309 4-Heptenoic acid, 7-(5-((1,1'-biphenyl)-4-ylmethoxy)-3-hydroxy-2-(1-piperidinyl)cyclopentyl)-, (1R-(1alpha(Z),2beta,3beta,5alpha))- Unii-H84xt1coau Vapiprost [inn:ban] Vapiprostum (4Z)-7-[(1R,2R,3S,5S)-5-([1,1'-BIPHENYL]-4-YLMETHOXY)-3-HYDROXY-2-(1-PIPERIDINYL)CYCLOPENTYL]-4-HEPTENOIC ACID HYDROCHLORIDE GR 32191B GR 32191 HYDROCHLORIDE Vapiprost Vapiprostum [latin] 4-Heptenoic acid, 7-[(1R,2R,3S,5S)-5-([1,1'-biphenyl]-4-ylmethoxy)-3-hydroxy-2-(1-piperidinyl)cyclopentyl]-, (4Z)- 85505-64-2