Diisobutylaluminium hydride
![Diisobutylaluminium hydride Structure](CAS/GIF/1191-15-7.gif)
- CAS No.
- 1191-15-7
- Chemical Name:
- Diisobutylaluminium hydride
- Synonyms
- DIBAL-H;Dibal;DIISOBUTYLALUMINUM HYDRIDE;DIBAH;Diisobutylaluminum;Bis(2-methylpropyl)alumane;Bisisobutylaluminum;Diisobutylaluminum hydrid;diisobutylaluminum hydride solution;DiisobutylaluMinuM hydride solution 1.0 M in cyclohexane
- CBNumber:
- CB4171924
- Molecular Formula:
- C8H19Al
- Molecular Weight:
- 142.22
- MOL File:
- 1191-15-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/15 16:45:23
Melting point | -70 °C |
---|---|
Boiling point | 65 °C |
Density | 1.23 g/mL at 25 °C |
vapor pressure | 13.3Pa at 90℃ |
Flash point | 40 °F |
storage temp. | 2-8°C |
solubility | Miscible with organic solvents. |
form | Solution |
color | Clear |
Specific Gravity | 0.860 |
Water Solubility | vigorous reaction |
Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
Sensitive | Air Sensitive/Heat Sensitive |
BRN | 4123663 |
Exposure limits |
ACGIH: TWA 20 ppm OSHA: Ceiling 300 ppm; TWA 200 ppm NIOSH: IDLH 500 ppm; TWA 100 ppm(375 mg/m3); STEL 150 ppm(560 mg/m3) |
InChIKey | AZWXAPCAJCYGIA-UHFFFAOYSA-N |
LogP | 4.22 |
CAS DataBase Reference | 1191-15-7(CAS DataBase Reference) |
NIST Chemistry Reference | Diisobutylaluminum hydride(1191-15-7) |
EPA Substance Registry System | Diisobutylaluminum hydride (1191-15-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() ![]() ![]() GHS02,GHS05,GHS07,GHS08 |
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Signal word | Danger | |||||||||
Hazard statements | H225-H250-H260-H304-H314-H336-H361d-H373-H412 | |||||||||
Precautionary statements | P210-P231+P232-P280-P301+P310+P331-P301+P330+P331-P303+P361+P353-P305+P351+P338+P310-P370+P378 | |||||||||
Hazard Codes | F,T,C,N | |||||||||
Risk Statements | 14/15-17-35-40-67-65-63-48/20-11-34-19-62-51/53-23/24/25-20/21/22-15-14-50/53-37-22 | |||||||||
Safety Statements | 26-43-45-62-46-36/37/39-29-16-61-27-9 | |||||||||
RIDADR | UN 3399 4.3/PG 1 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | BD0710000 | |||||||||
F | 1-4.3-10 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 4.3 | |||||||||
PackingGroup | I | |||||||||
HS Code | 29319090 | |||||||||
NFPA 704 |
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Diisobutylaluminium hydride price More Price(19)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 215007 | Diisobutylaluminum hydride solution 1.0?M in toluene | 1191-15-7 | 100ML | ₹8649.18 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 215007 | Diisobutylaluminum hydride solution 1.0?M in toluene | 1191-15-7 | 4X25ML | ₹9590.95 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 215007 | Diisobutylaluminum hydride solution 1.0?M in toluene | 1191-15-7 | 800ML | ₹40344.78 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 214981 | Diisobutylaluminum hydride solution 1.0?M in THF | 1191-15-7 | 100ML | ₹7090.38 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 214981 | Diisobutylaluminum hydride solution 1.0?M in THF | 1191-15-7 | 4X25ML | ₹8584.23 | 2022-06-14 | Buy |
Diisobutylaluminium hydride Chemical Properties,Uses,Production
Description
Diisobutylaluminium hydride (DIBALH, DIBAL, DIBAL-H or DIBAH) is a reducing agent with the formula (i-Bu2AlH)2, where i-Bu represents isobutyl (-CH2CH(CH3)2). It can be used for various homogeneous reductions such as alkynes to alkenes, esters or nitriles to aldehydes. It is available commercially as the neat reagent and as a solution in several different solvents (hexane, dichloromethane, tetrahydrofuran, etc.). The neat reagent is a liquid and is supplied in metal cylinders. It is pyrophoric and highly reactive and therefore must be handled with great care. The molar solutions in organic solvents are more stable and easier to handle provided that the normal precautions are taken for working with air-sensitive compounds. They must all be handled in an atmosphere free from oxygen and water. Commonly used solvents for diisobutylaluminium hydride are dichloromethane, diglyme, dioxane and tetrahydrofuran. Even when the substrate is not completely soluble in these solvents successful reductions can be accomplished.
Chemical Properties
Diisobutylaluminium hydride, also known as Dibal. colorless liquid. Viscosity 18.0mPa-s(25℃). Reacts violently with water to form hydrogen and isobutane. Tetrahydrofuran is not suitable as Dibal solvent, because the two react to produce coordination compounds. Diisobutylaluminium hydride is a useful reducing agent in organic synthesis. It can reduce ketones, carboxylic acids and esters to the corresponding alcohols. Dibal can also reduce lactones to o-hydroxy lactones.
Uses
Diisobutylaluminum hydride is commonly used as a reducing agent in organic synthesis.
Diisobutylaluminum hydride can be used in the following protocols:
As a promotor of Tishchenko reaction of aldehydes.
Conversion of benzylidene acetals of 1,2-and 1,3-glycols to the corresponding monobenzyl ethers of the glycols.
To generate a novel chiral reducing agent based on (S)-proline for the asymmetric reduction of prochiral ketones.
Safety Profile
Mddly toxic by inhalation. Dangerous fire hazard; iptes spontaneously in air. To fight fire, do not use water, foam, or halogenated extinguisking agents. See also HYDRIDES and ALUMINUM COMPOUNDS.
Diisobutylaluminium hydride Preparation Products And Raw materials
Raw materials
Preparation Products
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Supplier | Advantage |
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Almas Life Sciences | 58 |
JIVICHEM SYNTHESIS PVT LTD | 58 |
AMINO ORGANICS | 58 |
Otto Chemie Pvt Ltd | 58 |
Organo Metallics | 58 |
JSK Chemicals | 58 |
CLEARSYNTH LABS LTD. | 58 |
Otto Chemie Pvt. Ltd. | 58 |
Alfa Aesar | 58 |
Lalit Enterprises | 58 |
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