NEBULARINE
- CAS No.
- 550-33-4
- Chemical Name:
- NEBULARINE
- Synonyms
- NSC65423;NEBULARINE;Purinosine;ribosylpurine;ribosyl-purin;PURINE RIBOSIDE;Ribosyl-isopurine;6-deaMinoadenosine;PURINE RIBONUCLEOSIDE;9-purineribonucleoside
- CBNumber:
- CB9264951
- Molecular Formula:
- C10H12N4O4
- Molecular Weight:
- 252.23
- MOL File:
- 550-33-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 181-182°C |
|---|---|
| alpha | D25 -48.6° (H2O) |
| Boiling point | 395.4°C (rough estimate) |
| Density | 1.3402 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Ethanol, Methanol (Slightly) |
| pka | 13.13±0.70(Predicted) |
| form | Solid |
| color | Pale Beige to Beige |
| Merck | 13,6461 |
| Stability | Hygroscopic |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319-H335-H315 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RTECS | UO9100000 | |||||||||
| Toxicity | LD50 in rats, guinea pigs (mg/kg): 220, 15 s.c. (Truant, D'Amato) | |||||||||
| NFPA 704 |
|
NEBULARINE Chemical Properties,Uses,Production
Description
This purine base is produced by Agarius nebularis Batsch. (Syn. Clitocybe nebularis). It is laevorotatory with [α]25D - 48.6° (c 1.0, H20).
Chemical Properties
Crystalline Solid
Uses
Nebularine is shown to have inhibitory effects against mouse Sarcoma 180 and mycobacteria.
Definition
ChEBI: A purine ribonucleoside that is 9H-purine attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage.
Purification Methods
Nebularine is recrystallised from butanone/MeOH or EtOH and forms a MeOH photo-adduct. It is a strong inhibitor of adenosine deaminase [EC 3.5.4.4]. [Nair & Weichert Bioorg Chem 9 423 1980, Lfgren et al. Acta Chem Scand 7 225 1953, UV: Brown & Weliky J Biol Chem 204 1019 1953, Beilstein 26 III/IV 1740.]
NEBULARINE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 94)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10311 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | China | 4088 | 58 | Inquiry |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
| BOC Sciences | 16314854226; +16314854226 | United States | 19743 | 58 | Inquiry |
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | China | 9980 | 58 | Inquiry |
| Wuhu Nuowei chemistry Co., Ltd. | +86-0553-2911116-802 +undefined17756524438 | China | 1640 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| CHEMSWORTH | 30 |
| career henan chemical co | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | 58 |
| BOC Sciences | 58 |
| NewCan Biotech Limited | 58 |
| Wuhu Nuowei chemistry Co., Ltd. | 58 |
550-33-4(NEBULARINE)Related Search:
Adenosine 5'-monophosphate monohydrate
2-Amino-6-chloropurine-9-riboside
8-BROMOADENOSINE
6-Chloropurine ribonucleoside
N6-ISOPENTENYLADENOSINE-D6
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9-(beta-d-ribofuranosyl)purine
9-beta-d-ribofuranosyl-9h-purin
9-beta-d-ribofuranosyl-9h-purine
9-purineribonucleoside
ribosyl-purin
ribosylpurine
1-(9H-Purine-9-yl)-1-deoxy-β-D-ribofuranose
9-β-D-Ribofuranosyl-9H-purine
PURINE RIBONUCLEOSIDE
PURINE RIBOSIDE
PURINE 9BETA-D-RIBOFURANOSIDE
NEBULARINE
Purine-9-D-Ribofuranoside
9H-Purine, 9-.beta.-D-ribofuranosyl-
NSC65423
Nebularine (high purity)
9-beta-D-Ribosyl-9H-purine
Purinosine
Ribosyl-isopurine
6-deaMinoadenosine
9H-Purine, 9-β-D-ribofuranosyl-
6-Deaminoadenosine, purine riboside, Nabularine
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diol
Nebularine,6-Deamino adenosine
550-33-4
Sugars, Carbohydrates & Glucosides
Bases & Related Reagents
Nucleotides