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N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine Structure
CAS No.
1421372-94-2
Chemical Name:
N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine
Synonyms
N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine;N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine;AZD9291 1;EOS-61221;AZD9291 N-3;Osimertinib N-3;AZD9291 Intermediate 2;OSIMERTINIB INTERMEDIATE 1;Osimertinib mesylate intermediate 1;N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)p...
CBNumber:
CB92710519
Molecular Formula:
C20H16FN5O3
Molecular Weight:
393.37
MOL File:
1421372-94-2.mol
MSDS File:
SDS
Modify Date:
2025/3/6 8:32:39
Request For Quotation

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine Properties

Melting point >250°C (dec.)
Boiling point 639.3±65.0 °C(Predicted)
Density 1.41±0.1 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility DMSO (Slightly, Heated)
pka 2.02±0.10(Predicted)
form Solid
color Light Yellow to Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H335-H319
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine Chemical Properties,Uses,Production

Uses

N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine functions as a reagent in the synthesis of dihydropyrroloquinoline derivatives with anticancer activity as EGFR modulator to inhibit L858R/T790M.

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine Preparation Products And Raw materials

Raw materials

3-(2-chloropyriMidin-4-yl)-1-Methylindole 4-fluoro-2-Methoxy-5-nitroaniline 1-Methylindole 2,4-DIFLUORO-5-NITROANILINE 3-(2-chloropyriMidin-4-yl)-1H-indole
4-FLUORO-2-METHOXYANILINE Indole 2,4-Difluoroaniline
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Preparation Products

AZ 7550

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine Suppliers

Global( 235)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Bulat Pharmaceutical Pvt Ltd +91-8448085659 +91-8448085660 Haryana, India 123 58 Inquiry
Vidgas science and technologies Pvt Ltd +91-9030019844 +91-9030019844 Telangana, India 76 58 Inquiry
Rivashaa Agrotech Biopharma Pvt. Ltd. +91-26463395 +91-7926462688 Gujarat, India 1615 58 Inquiry
ALS INDIA LIFE SCIENCES +91-8977036379 +91-8977036379 Hyderabad, India 1878 58 Inquiry
Aarti Industries Limited (AIL) +91-84596144931 +91-9920899935 Maharashtra, India 235 58 Inquiry
Avra Laboratories Pvt Ltd +91-8008572391 +91-8008572391 Hyderabad, India 43 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
Suzhou Victorypharm Co.,Ltd. +86-13916956214 China 1299 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20232 58 Inquiry
Supplier Advantage
Bulat Pharmaceutical Pvt Ltd 58
Vidgas science and technologies Pvt Ltd 58
Rivashaa Agrotech Biopharma Pvt. Ltd. 58
ALS INDIA LIFE SCIENCES 58
Aarti Industries Limited (AIL) 58
Avra Laboratories Pvt Ltd 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Suzhou Victorypharm Co.,Ltd. 58
Henan Fengda Chemical Co., Ltd 58

1421372-94-2(N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine)Related Search:

AZD-9291 N-(5-Chloro-2-methylphenyl)-7- nitrobenzo[c][1,2,5]oxadiazol-4-amine N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE 1,4-BenzenediaMine, N1-[2-(diMethylaMino)ethyl]-5-Methoxy-N1-Methyl-N4-[4-(1-Methyl-1H-indol-3-yl)-2-pyriMidinyl]-2-nitro- Mutated EGFR-IN-1
N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine 2-PyriMidinaMine, N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methyl-1H-indol-3-yl)- (4-Fluoro-2-methoxy-5-nitro-phenyl)-[4-(1-methyl-1h-indol-3-yl)-pyrimidin-2-yl]-amine AZD9291 1 OSIMERTINIB INTERMEDIATE 1 N-(4-fluoro-2-methoxy-5-nitrophenyl)- 4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) EOS-61221 N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-3-indolyl)-2-pyrimidinamine AZD9291 N-3 Osimertinib mesylate intermediate 1 AZD9291 Intermediate 2 N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)p... N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine,99% Osimertinib N-3 1421372-94-2 AZD9291 1421372-94-2