Cilazapril
- CAS No.
- 88768-40-5
- Chemical Name:
- Cilazapril
- Synonyms
- Vascace;(1S,9S)-;Yipingshu;Ro34-2848;Cilazapril;Ro 31-2848;Ro 34-2848;Ro-34-2848;CILASTATIN NA;Cilazapril USP/EP/BP
- CBNumber:
- CB9307140
- Molecular Formula:
- C22H31N3O5
- Molecular Weight:
- 417.5
- MOL File:
- 88768-40-5.mol
- Modify Date:
- 2023/5/18 11:30:59
| Melting point | 95-97°C |
|---|---|
| Boiling point | 598.1±60.0 °C(Predicted) |
| Density | 1.26±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly) |
| form | powder |
| pka | 2.28±0.20(Predicted) |
| color | White to Off-White |
| CAS DataBase Reference | 88768-40-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | MJ9650200 |
Cilazapril Chemical Properties,Uses,Production
Description
Cilazapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor cilazaprilat. In vivo, cilazapril (0.1 mg/kg) inhibits plasma ACE activity and inhibits the angiotensin I-induced pressor response in anesthetized rats and cats. It decreases systolic blood pressure in spontaneously hypertensive rats when administered at a dose of 30 mg/kg. Cilazapril (10 mg/kg, p.o.) decreases blood pressure in volume-depleted renal hypertensive dogs. Formulations containing cilazapril have been used in the treatment of hypertension.
Chemical Properties
Off-White Solid
Cilazapril Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 82)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Glenmark Pharmaceuticals Limited | +912240189999 | Maharashtra, India | 93 | 58 | Inquiry |
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Sun Pharmaceutical Industries Ltd | +91-2242244224 +91-2243244324 | Maharashtra, India | 108 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Hetero Labs Limited | 09347706962 | Hyderabad, India | 14 | 58 | Inquiry |
| HETERO DRUGS LIMITED | +91 40 23704923 | New Delhi, India | 56 | 58 | Inquiry |
| Ranbaxy Laboratories Limited | (+91 22) 4324 4324 | New Delhi, India | 76 | 58 | Inquiry |
| HETERO LABS LTD | (630) 931-6800 | New Delhi, India | 97 | 58 | Inquiry |
| GLENMARK LIFE SCIENCES LIMITED | 91 2189 234456 | New Delhi, India | 22 | 58 | Inquiry |
88768-40-5(Cilazapril)Related Search:
CILAZAPRIL EPC(CRM STANDARD),CILAZAPRIL EPC(
DELAPRIL
Lithium diisopropylamide
DIAZOXIDE
Carbonyl iron powder
NITROUS OXIDE
Ethyl N-(2-butyl)glycinate
2,2'-(ETHYLENEDIIMINO)-DIBUTYRIC ACID
Cilastatin
Cilazaprilat
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6H-Pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, 9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-, (1S,9S)-
6H-Pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, 9-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-, [1S-[1α,9α(R*)]]-
Ro 31-2848
Yipingshu
CILASTATIN NA
CILASTATIN SODIUM SALT
sodium hydrogen 7-[(2-amino-2-carboxylatoethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]hept-2-enoate
(1S,9S)-9-[(S)-1-Ethoxycarbonyl-3-phenylpropylamino]-10-oxoperhydropyridazino[1,2-a][1,2]diazepine-1-carboxylic acid
Cilazapril
(1S,9S)-9-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-α][1,2]diazepine-1-carboxylic Acid
Vascace
(1S,9S)-9-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid
(1S,9S)-9-[[(S)-1-Ethoxycarbonyl-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid
(1S,9S)-
(1S,9S)-9-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic Acid
Cilazapril USP/EP/BP
Cilazapril (anhydrous)
Ro 34-2848
Ro-34-2848
Ro34-2848
88768-40-5
Chiral Reagents
API
Intermediates & Fine Chemicals
Pharmaceuticals