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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Bromopyrimidine >2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE

2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE

2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Structure
CAS No.
19752-61-5
Chemical Name:
2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE
Synonyms
IFLAB-BB F1371-0151;2,4-DI-T-BUTOXY-5-BROMO-PYRIMIDINE;Oxirane, 2-[14-(phenylMethoxy)ethyl]-;5-broMo-2,4-bis(tert-butoxy)pyriMidine;2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE;5-BROMO-2,4-DI-(TERT-BUTOXY)PYRIMIDINE;5-Bromo-2,4-di-(tert-butoxy)pyrimidine 95%;5-BroMo-2,4-bis(1,1-diMethylethoxy)pyriMidine;Pyrimidine, 5-bromo-2,4-bis(1,1-dimethylethoxy)-;Benzaldehyde,4-(4,6-dichloro-1,3,5-triazin-4-yl)-
CBNumber:
CB9323582
Molecular Formula:
C12H19BrN2O2
Molecular Weight:
303.2
MOL File:
19752-61-5.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06
Request For Quotation

2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Properties

Melting point 58-61°C
Boiling point 352.0±45.0 °C(Predicted)
Density 1.267±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DCM, Ethyl Acetate, Methanol
pka 1.73±0.29(Predicted)
form Solid
color White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
HS Code  2933998090
NFPA 704
1
2 0

2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Chemical Properties,Uses,Production

Uses

5-Bromo-2,4-bis(1,1-dimethylethoxy)pyrimidine is an intermediate in the synthesis of β-Pseudouridine (O839607), an isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA.

Synthesis

1.jpg
5-Bromo-2,4-dichloropyrimidine (10.0 mmol, 2.28 g) is dissolved in dry THF (50 mL). Then a solution of sodium tert-butoxide (25.0 mmol, 2.40 g) in THF (100 mL) is added dropwise at rt and the reaction mixture stirred for 5 h. The reaction is quenched with water (50 mL) and extracted with EtOAc (3 x 50 mL). Purification by flash chromatography yielded the desired product 5 as colorless solid (2.79 g, 92%). 5-Bromo-2,4-di-tert-butoxypyrimidine 5 ,Yield 2.79 g, 92%.

2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Preparation Products And Raw materials

Raw materials

Ethanol 5-Bromo-2,4-dichloropyrimidine Toluene Sodium tert-Butanol

Preparation Products

2,4-DI(TERT-BUTOXY)PYRIMIDIN-5-YLBORONIC ACID HYDRATE

2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE Suppliers

Global( 85)Suppliers
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Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
LABEX CORPORATION 08068441104Ext 410 Delhi, India 117 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 25808 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
Supplier Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd 58
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
Pharma Affiliates 58
Clearsynth Labs 58
LABEX CORPORATION 58
CONIER CHEM AND PHARMA LIMITED 58
Dideu Industries Group Limited 58
Dayang Chem (Hangzhou) Co.,Ltd. 58
Zhejiang J&C Biological Technology Co.,Limited 58

19752-61-5(2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE)Related Search:

5-Bromopyrimidine 2,4-DIETHOXYPYRIMIDINE 5-BROMO-2-(TERT-BUTOXY)PYRIMIDINE 5-Bromo-2-methoxypyrimidine 5-bromo-1H-pyrimidin-4-one
5-BROMO-2,4-DIMETHOXYPYRIMIDINE 2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE 5-BROMO-2-HYDROXYPYRIMIDINE 5-BROMO-2-ETHOXY-PYRIMIDINE
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IFLAB-BB F1371-0151 5-BROMO-2,4-DI-(TERT-BUTOXY)PYRIMIDINE 2,4-DI-T-BUTOXY-5-BROMO-PYRIMIDINE 2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE 5-broMo-2,4-bis(tert-butoxy)pyriMidine 5-BroMo-2,4-bis(1,1-diMethylethoxy)pyriMidine 5-bromo-2,4-bis[(2-methylpropan-2-yl)oxy]pyrimidine 5-Bromo-2,4-di-(tert-butoxy)pyrimidine 95% Pyrimidine, 5-bromo-2,4-bis(1,1-dimethylethoxy)- 2,4-DI-(TERT-BUTOXY)-5-BROMOPYRIMIDINE ISO 9001：2015 REACH Benzaldehyde,4-(4,6-dichloro-1,3,5-triazin-4-yl)- Oxirane, 2-[14-(phenylMethoxy)ethyl]- 19752-61-5 Pyrimidines