Taurodeoxycholic acid sodium salt

- CAS No.
- 1180-95-6
- Chemical Name:
- Taurodeoxycholic acid sodium salt
- Synonyms
- SODIUM TAURODEOXYCHOLATE;Taurodeoxycholate sodium salt;Taurodeoxycholic acid sodium salt hydrate;5B2;12B1;sodium 2-[[(3B1;sodium taurodeoxylate;SodiuM taurodeoxycholat;Sodium deoxytaurocholate;Taurodeoxycholate sodium
- CBNumber:
- CB9349065
- Molecular Formula:
- C26H44NNaO6S
- Molecular Weight:
- 521.69
- MOL File:
- 1180-95-6.mol
- Modify Date:
- 2025/4/22 12:35:22
Melting point | 168 °C (dec.)(lit.) |
---|---|
alpha | 33 º (c=3, water) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | H2O: 0.5 M at 20 °C, clear, colorless to faintly yellow |
pka | 1.9 |
form | Solid |
color | White to Off-White |
Water Solubility | soluble |
InChIKey | YXHRQQJFKOHLAP-UROAIUCXNA-M |
CAS DataBase Reference | 1180-95-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H335-H319 |
Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
Hazard Codes | Xi |
Risk Statements | 37 |
Safety Statements | 24/25 |
WGK Germany | 3 |
F | 3-10 |
HS Code | 29242990 |
Taurodeoxycholic acid sodium salt price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
SRL | 57861 | Sodium Taurodeoxycholate Dried (STDC Dried) extrapure, 97% | 1180-95-6 | 1Gms | ₹2500 | 2022-05-26 | Buy |
SRL | 57861 | Sodium Taurodeoxycholate Dried (STDC Dried) extrapure, 97% | 1180-95-6 | 5Gms | ₹8230 | 2022-05-26 | Buy |
ottokemi | S 8091 | Sodium taurodeoxycholate, hydrate, ≥95% (HPLC) | 1180-95-6 | 5gm | ₹13509 | 2022-05-26 | Buy |
SRL | 57861 | Sodium Taurodeoxycholate Dried (STDC Dried) extrapure, 97% | 1180-95-6 | 25Gms | ₹38560 | 2022-05-26 | Buy |
ottokemi | S 8091 | Sodium taurodeoxycholate, hydrate, ≥95% (HPLC) | 1180-95-6 | 50gm | ₹48069 | 2022-05-26 | Buy |
Taurodeoxycholic acid sodium salt Chemical Properties,Uses,Production
Chemical Properties
white to almost white crystalline powder
Uses
Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.
Purification Methods
The Na salt is dissolved in the smallest volume of H2O, a saturated solution of aqueous NaCl/Et2O is added and the mixture is stored at 0o for 24hours. Then shake the mixture well, keep it in the cold for another day and filter the crystals with gentle shaking, wash them with ice-cold saturated aqueous NaCl saturated with Et2O, dry them over CaCl2 and extract them with absolute EtOH. Add ~10mL of H2O to the solid followed by enough Et2O to incipient cloudiness. Store it overnight at 0o. Add ice-cold Et2O to make 250mL, collect the crystals, wash them with Et2O then pet ether and dry them in air. The purification can be repeated with NaCl and Et2O with ~85% recovery. NB: precipitation will not occur unless enough H2O is present. Its solubility in H2O is 10%. [Cortese J Am Chem Soc 59 2532 1937.] The free acid has m 141-144o. [Norman Ark Kemi 8 331 1956.] It forms mixed micelles and solubilises some membrane proteins [Hajjar et al. J Biol Chem 2 5 8 192 1983]. [Beilstein 10 IV 1611.]
Taurodeoxycholic acid sodium salt Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Varanous Labs Pvt Ltd | +91-7036248882 +91-7036248882 | Hyderabad, India | 1537 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5870 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4315 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6088 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49734 | 58 | Inquiry |
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | China | 12809 | 58 | Inquiry |
Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | China | 18137 | 58 | Inquiry |
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