ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Neuronal Signaling >Dopamine Receptor agonists >Pergolide mesylate salt
Pergolide mesylate salt
- CAS No.
- 66104-23-2
- Chemical Name:
- Pergolide mesylate salt
- Synonyms
- MPE;Nopar;Permax;Celance;Veceral;Pergolin;ly127809;NSC 319773;PERGOLIDE MESYLATE;Pergolide mesilate CRS
- CBNumber:
- CB9455089
- Molecular Formula:
- C20H30N2O3S2
- Molecular Weight:
- 410.59
- MOL File:
- 66104-23-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/18 11:30:59
| Melting point | 252-254°C |
|---|---|
| alpha | aD20 between -18.0° and -23.0° (c = 10 mg/ml in DMF) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | ethanol: soluble2mg/mL |
| pka | pKa (66% DMF) 7.8(at 25℃) |
| form | solid |
| color | white |
| optical activity | [α]20/D 35°, c = 0.2 in pyridine(lit.) |
| InChIKey | UWCVGPLTGZWHGS-PLBOZXOQNA-N |
| SMILES | C12=C3C=CC=C1[C@@]1([H])C[C@H](CN(CCC)[C@]1([H])CC2=CN3)CSC.S(=O)(=O)(O)C |&1:6,9,15,r| |
| CAS DataBase Reference | 66104-23-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300 |
| Precautionary statements | P301+P330+P331+P310 |
| Hazard Codes | T+ |
| Risk Statements | 28 |
| Safety Statements | 28-36/37-45 |
| RIDADR | UN 1544 |
| WGK Germany | 3 |
| RTECS | KE6345000 |
| HS Code | 2939690000 |
Pergolide mesylate salt Chemical Properties,Uses,Production
Description
Pergolide mesylate is a potent, long-acting dopamine agonist useful in the treatment of Parkinson’s disease and hyperprolactinemia, Compared with lergotrile, pergolide mesylate has shown less toxicity and lower propensity for inducing psychosis.
Chemical Properties
White to Off-White Solid
Uses
A dopaminergic agonist that also decrease plasma prolactin concentrations. An antiparkinsonian agent
Definition
ChEBI: A methanesulfonate salt obtained from pergolide by mixing eqimolar amount of pergolide and methanesulfonic acid. A dopamine D2 receptor agonist which also has D1 and D2 agonist properties, it i used in the management of Parkinson's disease, although it was withdrawn from the U.S. and Canadian markets in 2007 due to an increased risk of cardiac valve dysfunction.
Pergolide mesylate salt Preparation Products And Raw materials
Global( 148)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Tianjin Kilo Pharmaceutical Sci-Tech Co., Ltd | +86-02223869539 +86-15560057295 | China | 27 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | China | 2931 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49392 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24200 | 58 | Inquiry |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | China | 9640 | 58 | Inquiry |
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66104-23-2
C20H30N2O3S2
C21H18N3O2
C19H26N2SCH4O3S
LOCOID
API
Intermediates & Fine Chemicals
Neurochemicals
Pharmaceuticals