2-Nitrofluorene
- CAS No.
- 607-57-8
- Chemical Name:
- 2-Nitrofluorene
- Synonyms
- 2-Nitro-9H-fluorene;2-Nitrof;atinum powder;2-NITROFLUORENE;2-NITROFLUOROENE;2-nitro-9h-fluoren;2-Nitrofluorene >2-Nitrofluorene,98%;2-Nitrofluorene,99%;9H-Fluorene, 2-nitro-
- CBNumber:
- CB9462399
- Molecular Formula:
- C13H9NO2
- Molecular Weight:
- 211.22
- MOL File:
- 607-57-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/4/23 13:52:06
| Melting point | 156-158 °C (lit.) |
|---|---|
| Boiling point | 350.9°C (rough estimate) |
| Density | 1.1868 (rough estimate) |
| refractive index | 1.6060 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Powder |
| color | White to brown |
| Water Solubility | Insoluble |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 607-57-8(CAS DataBase Reference) |
| IARC | 2B (Vol. 46, 105) 2014 |
| NIST Chemistry Reference | Fluorene, 2-nitro-(607-57-8) |
| EPA Substance Registry System | 2-Nitrofluorene (607-57-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H351-H411 | |||||||||
| Precautionary statements | P201-P273-P308+P313 | |||||||||
| Hazard Codes | Xn,N | |||||||||
| Risk Statements | 40-51/53-68 | |||||||||
| Safety Statements | 36/37-61 | |||||||||
| RIDADR | UN 3077 9/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LL8225000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 9 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29042000 | |||||||||
| NFPA 704 |
|
2-Nitrofluorene price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | N16754 | 2-Nitrofluorene 98% | 607-57-8 | 5G | ₹6498.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N16754 | 2-Nitrofluorene 98% | 607-57-8 | 25G | ₹16215.35 | 2022-06-14 | Buy |
| TCI Chemicals (India) | N0201 | 2-Nitrofluorene | 607-57-8 | 25G | ₹7200 | 2022-05-26 | Buy |
| TCI Chemicals (India) | N0201 | 2-Nitrofluorene | 607-57-8 | 100G | ₹7500 | 2022-05-26 | Buy |
| ALFA India | ALF-H55744-14 | 2-Nitrofluorene, 98% | 607-57-8 | 25g | ₹9207 | 2022-05-26 | Buy |
2-Nitrofluorene Chemical Properties,Uses,Production
Chemical Properties
cream powder
Uses
2-Nitrofluorene is a genotoxic compound and also a biomaker that affects the DNA of living organisms. An environmental pollutant.
Definition
ChEBI: A nitroarene that is fluorene substituted by a nitro group at position 2.
General Description
Cream-colored solid.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Aromatic nitro compounds, such as 2-Nitrofluorene, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. The aromatic nitro compounds may explode in the presence of a base such as sodium hydroxide or potassium hydroxide even in the presence of water or organic solvents. The explosive tendencies of aromatic nitro compounds are increased by the presence of multiple nitro groups. Stable under normal conditions. Protect from bases.
Health Hazard
ACUTE/CHRONIC HAZARDS: Toxic. Hazardous decomposition products. Carcinogen.
Safety Profile
Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by intraperitoneal route. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITRO COMPOUNDS OF AROMATIC HYDROCARBONS.
Metabolic pathway
Lung microsomal metabolism of 2-nitrofluorene (NF) increases in parallel with the accumulation of P-450b homologous mRNA and microsomal cytochrome P- 450b protein concentration. The formation of the major metabolite, and potent mutagen, 9-hydroxy-2- nitrofluorene (9-OHNF) is significantly inhibited by the addition of polyclonal anti-P-450b-IgG, and by the addition of the inhibitor, proadifen, to incubations with lung microsomal protein.
Purification Methods
Crystallise 2-nitrofluorene from aqueous acetic acid or Me2CO (m 158-158.5o, also 160-160.5o). [Beilstein 5 H 628, 5 III 1948.]
2-Nitrofluorene Preparation Products And Raw materials
Raw materials
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