2-Nitrofluorene

2-Nitrofluorene Structure
CAS No.
607-57-8
Chemical Name:
2-Nitrofluorene
Synonyms
2-Nitro-9H-fluorene;2-Nitrof;atinum powder;2-NITROFLUORENE;2-NITROFLUOROENE;2-nitro-9h-fluoren;2-Nitrofluorene >2-Nitrofluorene,98%;2-Nitrofluorene,99%;9H-Fluorene, 2-nitro-
CBNumber:
CB9462399
Molecular Formula:
C13H9NO2
Molecular Weight:
211.22
MOL File:
607-57-8.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

2-Nitrofluorene Properties

Melting point 156-158 °C (lit.)
Boiling point 350.9°C (rough estimate)
Density 1.1868 (rough estimate)
refractive index 1.6060 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Powder
color White to brown
Water Solubility Insoluble
Stability Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 607-57-8(CAS DataBase Reference)
IARC 2B (Vol. 46, 105) 2014
NIST Chemistry Reference Fluorene, 2-nitro-(607-57-8)
EPA Substance Registry System 2-Nitrofluorene (607-57-8)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS09
Signal word  Warning
Hazard statements  H351-H411
Precautionary statements  P201-P273-P308+P313
Hazard Codes  Xn,N
Risk Statements  40-51/53-68
Safety Statements  36/37-61
RIDADR  UN 3077 9/PG 3
WGK Germany  3
RTECS  LL8225000
TSCA  Yes
HazardClass  9
PackingGroup  III
HS Code  29042000
NFPA 704
1
0 0

2-Nitrofluorene price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) N16754 2-Nitrofluorene 98% 607-57-8 5G ₹6498.8 2022-06-14 Buy
Sigma-Aldrich(India) N16754 2-Nitrofluorene 98% 607-57-8 25G ₹16215.35 2022-06-14 Buy
TCI Chemicals (India) N0201 2-Nitrofluorene 607-57-8 25G ₹7200 2022-05-26 Buy
TCI Chemicals (India) N0201 2-Nitrofluorene 607-57-8 100G ₹7500 2022-05-26 Buy
ALFA India ALF-H55744-14 2-Nitrofluorene, 98% 607-57-8 25g ₹9207 2022-05-26 Buy
Product number Packaging Price Buy
N16754 5G ₹6498.8 Buy
N16754 25G ₹16215.35 Buy
N0201 25G ₹7200 Buy
N0201 100G ₹7500 Buy
ALF-H55744-14 25g ₹9207 Buy

2-Nitrofluorene Chemical Properties,Uses,Production

Chemical Properties

cream powder

Uses

2-Nitrofluorene is a genotoxic compound and also a biomaker that affects the DNA of living organisms. An environmental pollutant.

Definition

ChEBI: A nitroarene that is fluorene substituted by a nitro group at position 2.

General Description

Cream-colored solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Aromatic nitro compounds, such as 2-Nitrofluorene, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. The aromatic nitro compounds may explode in the presence of a base such as sodium hydroxide or potassium hydroxide even in the presence of water or organic solvents. The explosive tendencies of aromatic nitro compounds are increased by the presence of multiple nitro groups. Stable under normal conditions. Protect from bases.

Health Hazard

ACUTE/CHRONIC HAZARDS: Toxic. Hazardous decomposition products. Carcinogen.

Safety Profile

Confirmed carcinogen with experimental carcinogenic and tumorigenic data. Moderately toxic by intraperitoneal route. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also NITRO COMPOUNDS OF AROMATIC HYDROCARBONS.

Metabolic pathway

Lung microsomal metabolism of 2-nitrofluorene (NF) increases in parallel with the accumulation of P-450b homologous mRNA and microsomal cytochrome P- 450b protein concentration. The formation of the major metabolite, and potent mutagen, 9-hydroxy-2- nitrofluorene (9-OHNF) is significantly inhibited by the addition of polyclonal anti-P-450b-IgG, and by the addition of the inhibitor, proadifen, to incubations with lung microsomal protein.

Purification Methods

Crystallise 2-nitrofluorene from aqueous acetic acid or Me2CO (m 158-158.5o, also 160-160.5o). [Beilstein 5 H 628, 5 III 1948.]

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