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Cyclosporin A-Derivative 1 Free base

Cyclosporin A-Derivative 1 Free base Structure
CAS No.
286852-20-8
Chemical Name:
Cyclosporin A-Derivative 1 Free base
Synonyms
Cyclosporin A-Derivative 1 Free base;N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-;Glycine, N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester
CBNumber:
CB94844681
Molecular Formula:
C65H117N11O14
Molecular Weight:
1276.69
MOL File:
286852-20-8.mol
Modify Date:
2023/5/29 8:28:42
Request For Quotation

Cyclosporin A-Derivative 1 Free base Properties

Boiling point 1225.9±65.0 °C(Predicted)
Density 1.093±0.06 g/cm3(Predicted)
solubility DCM, Methanol
form Solid
pka 13.07±0.46(Predicted)
color Off-White

Cyclosporin A-Derivative 1 Free base Chemical Properties,Uses,Production

Uses

N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester is an intermediate in the synthesis of Cyclosporin AM 4N (C989410), a metabolite of Cyclosporin A (C988900). Cyclosporin A is a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation.

Cyclosporin A-Derivative 1 Free base Preparation Products And Raw materials

Raw materials

SDZ 33-243 Methanol Trimethyloxonium Tetrafluoroborate

Preparation Products

Cyclosporin A-Derivative 1 Free base Suppliers

Global( 7)Suppliers
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MedChemExpress 021-58955995 United States 6398 58 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; China 29778 58 Inquiry
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BOC Sciences 58
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Shanghai Hao Zhun Biological Technology Co., Ltd. 58
MedChemExpress 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Cyclosporin A-Derivative 1 Free base N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl- Glycine, N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester 286852-20-8