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COLCHICOSIDE

COLCHICOSIDE Structure
CAS No.
477-29-2
Chemical Name:
COLCHICOSIDE
Synonyms
Nsc32992;Nsc624672;Aids012001;Aids-012001;Colchicine impurity D;COLCHICOSIDE IMPURITY;COLCHICOSIDE USP/EP/BP;3-Demethylcolchicine glucoside;Thiocolchicoside EP Impurity D;N-[(7S,12aRa)-3-(beta-D-Glucopyrano
CBNumber:
CB9512353
Molecular Formula:
C27H33NO11
Molecular Weight:
547.554
MOL File:
477-29-2.mol
Modify Date:
2024/8/5 20:55:42

COLCHICOSIDE Properties

Melting point 194-197°C
Boiling point 620.17°C (rough estimate)
Density 1.3430 (rough estimate)
refractive index 1.6400 (estimate)
storage temp. Refrigerator
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form A crystalline solid
pka 12.74±0.70(Predicted)
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501
NFPA 704
0
2 0

COLCHICOSIDE Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Solid

Uses

A significantly toxic Colchicine analog with no anti-inflammatory properties.

Purification Methods

Purify colchicoside by chromatography through alumina and eluting with CHCl3, then recrystallising from Me2CO, m 275-280o (after releasing solvent at 180o). It also crystallises from EtOH; see colchicine. The tetraacetate has m 175-177o, [] D 15 -57o (c 1, CHCl3). [Bellet et al. Ann Pharm Fr 10 241 1952, Chem Abstr 47 3323 1953, Beilstein 14 IV 946 for colchicine.]

COLCHICOSIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 62)Suppliers
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Chemicea Pharmaceuticals Pvt Ltd +91-918482849343 +91-8482849343 Mumbai, India 461 58 Inquiry
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Colchicine EP impurity D (Colchicoside) (S)-7-Acetylamino-6,7-dihydro-3-(β-D-glucopyranosyloxy)-1,2,10-trimethoxybenzo[a]heptalen-9(5H)-one Aids012001 Aids-012001 N-[3-(Hexopyranosyloxy)-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[A]heptalen-7-yl]acetamide Nsc32992 Nsc624672 (S)-N-[3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-triMethoxy-9-oxobenzo[a]heptalen-7-yl]acetaMide N-[(7S)-3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro- 1,2,10-triMethoxy-9-oxobenzo[a]heptalen-7-yl]acetaMide 3-Demethylcolchicine glucoside Colchicine Impurity 4(Colchicine EP Impurity D) Colchicine impurity D N-[(7S,12aRa)-3-(beta-D-Glucopyrano COLCHICOSIDE IMPURITY Acetamide, N-[(7S)-3-(β-D-glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]- Thiocolchicoside EP Impurity D N-((S)-1,2,10-trimethoxy-9-oxo-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide COLCHICOSIDE USP/EP/BP ColchicosideQ: What is Colchicoside Q: What is the CAS Number of Colchicoside Q: What is the storage condition of Colchicoside Q: What are the applications of Colchicoside N-[(7S,12aRa)-3-(β-D-glucopyranosyloxy)-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide (colchicoside) 477-29-2 Miscellaneous Natural Products Carbohydrates & Derivatives Intermediates & Fine Chemicals Pharmaceuticals