NICOTINIC ACID MONONUCLEOTIDE

NICOTINIC ACID MONONUCLEOTIDE Structure
CAS No.
321-02-8
Chemical Name:
NICOTINIC ACID MONONUCLEOTIDE
Synonyms
β-NaMN;β-Nicotinic Acid Mon;Nicotinic Acid Ribotide;Nicotinic Mononucleotide;nicotinatemononucleotide;Nicotinate Ribonucleotide;Nicotinic Acid Ribonucleotide;NICOTINIC ACID MONONUCLEOTIDE;β-NicotinicAcidMononucleotide;3-Carboxy-1-methylpyridiniumiodid
CBNumber:
CB9670381
Molecular Formula:
C11H14NO9P
Molecular Weight:
335.2
MOL File:
321-02-8.mol
MSDS File:
SDS
Modify Date:
2023/11/15 17:30:31

NICOTINIC ACID MONONUCLEOTIDE Properties

Melting point >115°C (dec.)
storage temp. −20°C
solubility Methanol (Slightly, Heated), Water(Slightly)
form Solid
color White to Off-White
Stability Hygroscopic
InChI InChI=1/C11H14NO9P/c13-8-7(5-20-22(17,18)19)21-10(9(8)14)12-3-1-2-6(4-12)11(15)16/h1-4,7-10,13-14H,5H2,(H2-,15,16,17,18,19)/t7-,8-,9-,10-/s3
InChIKey JOUIQRNQJGXQDC-NLNRFTKUNA-N
SMILES [C@@H]1([C@H](O)[C@H](O)[C@@H](COP([O-])(=O)O)O1)[N+]1C=CC=C(C(=O)O)C=1 |&1:0,1,3,5,r|

SAFETY

Risk and Safety Statements

WGK Germany  3

NICOTINIC ACID MONONUCLEOTIDE Chemical Properties,Uses,Production

Uses

A nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH.

Synthesis

Nicotinic acid mononucleotide is prepared by the reaction of 2,3-dicarboxypyridine and 5-phosphoribosyl-1-pyrophosphate. The steps are as follows:
With phosphoribosyl pyrophosphate-quinolinate phosphoribosyltransferase; magnesium chloride In aq. phosphate buffer at 37℃; for 6h; pH=7.0; Enzymatic reaction.
Nicotinic acid mononucleotide synthesis

NICOTINIC ACID MONONUCLEOTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

NICOTINIC ACID MONONUCLEOTIDE Suppliers

Global( 50)Suppliers
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Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
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Maintain Biotech Co., Ltd. +86-75589664337 +86-15112661142 China 66 58 Inquiry
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Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
NewCan Biotech Limited +86-0571-86912261 +8613735419629 China 9980 58 Inquiry
changzhou huayang technology co., ltd +8615250961469 China 9827 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
nicotinatemononucleotide NICOTINIC ACID MONONUCLEOTIDE 1-[3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]pyridine-5-carboxylate 3-Carboxylato-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium 3-Carboxy-1-(5-O-phosphono-β-D-ribofuranosyl)pyridiniuM Inner Salt 3-Carboxy-1-β-D-ribofuranosylpyridiniuM Hydroxide 5'-Phosphate Inner Salt Nicotinate Ribonucleotide Nicotinic Acid Ribonucleotide Nicotinic Acid Ribotide Nicotinic Mononucleotide β-NaMN β-NicotinicAcidMononucleotide 3-Carboxy-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium 3-Carboxy-1-methylpyridiniumiodid β-Nicotinic Acid Mon 321-02-8 C11H15NO9P C11H14NO9P Cofactors Enzymes, Inhibitors, and Substrates Oxidation-Reduction Biochemicals and Reagents BioChemical Aromatics Bases & Related Reagents Intermediates & Fine Chemicals Nicotine Derivatives Nucleotides Pharmaceuticals Cofactors Enzymes, Inhibitors, and Substrates Oxidation-Reduction Amines