Methyl nicotinate
- CAS No.
- 93-60-7
- Chemical Name:
- Methyl nicotinate
- Synonyms
- NICOTINIC ACID METHYL ESTER;METHYL PYRIDINE-3-CARBOXYLATE;Nikomet;METHYL 3-PYRIDINECARBOXYLATE;Nicometh;FEMA 3709;Methyl nictinate;AKOS BBS-00004415;METHYL NICOTINATE;Methyl Nicotinatey
- CBNumber:
- CB1173538
- Molecular Formula:
- C7H7NO2
- Molecular Weight:
- 137.14
- MOL File:
- 93-60-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/25 20:04:51
| Melting point | 42-44 °C (lit.) |
|---|---|
| Boiling point | 204 °C (lit.) |
| Density | 1.2528 (rough estimate) |
| vapor pressure | 0.4 hPa (25 °C) |
| refractive index | 1.5323 (estimate) |
| FEMA | 3709 | METHYL NICOTINATE |
| Flash point | 204 °F |
| storage temp. | Store below +30°C. |
| solubility | H2O: 0.1 g/mL, clear |
| pka | pKa 3.1 (Uncertain) |
| form | Crystals or Crystalline Powder |
| color | White to brownish |
| Odor | at 10.00 % in dipropylene glycol. warm herbal tobacco |
| Odor Type | herbal |
| Water Solubility | NEGLIGIBLE |
| JECFA Number | 1320 |
| Merck | 14,6100 |
| BRN | 113951 |
| InChIKey | YNBADRVTZLEFNH-UHFFFAOYSA-N |
| LogP | 0.68 at 25℃ |
| CAS DataBase Reference | 93-60-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Methyl nicotinate(93-60-7) |
| EPA Substance Registry System | Methyl nicotinate (93-60-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-36/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | QT1925000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29333999 | |||||||||
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg | |||||||||
| NFPA 704 |
|
Methyl nicotinate price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | W370908 | Methyl nicotinate ≥99%, FG | 93-60-7 | 1SAMPLE-K | ₹5141.88 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W370908 | Methyl nicotinate ≥99%, FG | 93-60-7 | 5KG | ₹61897.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M59203 | Methyl nicotinate 99% | 93-60-7 | 5G | ₹1861.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M59203 | Methyl nicotinate 99% | 93-60-7 | 100G | ₹2002.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1835 | Methyl Nicotinate Pharmaceutical Secondary Standard; Certified Reference Material | 93-60-7 | 500MG | ₹10619.33 | 2022-06-14 | Buy |
Methyl nicotinate Chemical Properties,Uses,Production
Description
Methyl nicotinate is a skin irritant in man, in particular producing vasodilatation, which is used on purpose in “rubefacient”, to produce a redness or inflammation for a short period of time, often in lip plumper or other lip products. Methyl nicotinate is also an active ingredient of a number of veterinary preparations intended for topical application as a rubefacient for the treatment of a variety of diseases, such as respiratory diseases, vascular disorders (oedema, haematoma), and rheumatoid disorders in cattle and horses (doses not stated; the concentration in the formulated veterinary medicinal product is 2%).
Chemical Properties
Methyl nicotinate is white to brownish crystals or crystalline powder and has a fresh, caramellic, nutty and mild tobacco odor.
Occurrence
Reported found in ground coffee, roasted filberts, guanabana (Annona muicata L.), roasted peanuts, wild strawberries, vanilla bean, papaya, guava, plum, beer cognac, soursop, malt, wort, Bourbon vanilla and mountain papaya.
Uses
Methyl nicotinate (MN) is the methyl ester of nicotinic acid that is used as an active ingredient, a rubefacient and counter-irritant in over-the-counter topical preparations indicated for the temporary relief of aches and pains in muscles,tendons, and joints. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation.For veterinary purposes，methyl nicotinate is used to treat respiratory diseases, vascular disorders, rheumatoid arthritis, and muscle and joint pains.Methyl nicotinate can be found in in guava fruit, papaya, strawberry, soursop(Annona muricata), beer, grape brandy, coffee, roasted filbert, roasted peanut and Bourbon vanilla.
General Description
Methyl nicotinate (or nicotinic acid methyl ester) is used as a rubefacient for the relief of pains in muscles, tendons, and joints. It is also used in food as a flavoring agent.
Synthesis
Methyl nicotinate is synthesized from Nicotinyl chloride hydrochloride and and Methanol in presence of Pyridine.
Methyl nicotinate Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Terma Medicare India Pvt.,Ltd | +8613916485955 | Rajasthan, India | 145 | 58 | Inquiry |
| VRUDDISRI PHARMA | +91-9441446600 +91-9441446600 | Hyderabad, India | 70 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Saburi Life Sciences | +91-9052929666 +91-9177339666 | Hyderabad, India | 91 | 58 | Inquiry |
| ALS INDIA LIFE SCIENCES | +91-8977036379 +91-8977036379 | Hyderabad, India | 1879 | 58 | Inquiry |
| Anuja Healthcare Ltd | +91-6239597015 +91-9815004047 | Punjab, India | 26 | 58 | Inquiry |
| Krishna Chemicals | +91-9879575653 +91-8490013131 | Gujarat, India | 38 | 58 | Inquiry |
| Acharya Chemicals (Acharya Group) | +91-8291937381 +91-9820308443 | Maharashtra, India | 22 | 58 | Inquiry |
| Retrosynth Finechem Pvt Ltd | +91-9227230203 +91-9227230203 | Gujarat, India | 26 | 58 | Inquiry |
93-60-7(Methyl nicotinate)Related Search:
1of4
chevron_right