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Methyl 3-hydroxypropanoate

Methyl 3-hydroxypropanoate Structure
CAS No.
6149-41-3
Chemical Name:
Methyl 3-hydroxypropanoate
Synonyms
propanoic acid, 3-hydroxy-, methyl ester;HOCH2CH2C(O)OCH3;Methyl hydracrylate;Methyl3-hydroxypropionate;METHYL 3-HYDROXYPROPANOATE;Methyl beta-hydroxypropionate;Methyl gamma-hydroxypropionate;Hydracrylic acid, methyl ester;3-hydroxy-propanoicacidmethylester;3-Hydroxypropionic acid methyl ester
CBNumber:
CB9703300
Molecular Formula:
C4H8O3
Molecular Weight:
104.1
MOL File:
6149-41-3.mol
Modify Date:
2024/1/3 9:50:41

Methyl 3-hydroxypropanoate Properties

Melting point 147-148 °C(Solv: benzene (71-43-2); cyclohexane (110-82-7))
Boiling point 179°C (estimate)
Density 1.1050
refractive index 1.4300
storage temp. 2-8°C
solubility Chloroform, Methanol
form Oil
pka 13.89±0.10(Predicted)
color Colourless
InChI InChI=1S/C4H8O3/c1-7-4(6)2-3-5/h5H,2-3H2,1H3
InChIKey RVGLEPQPVDUSOJ-UHFFFAOYSA-N
SMILES C(OC)(=O)CCO

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS02
Signal word  Danger
Hazard statements  H315-H319-H225
Precautionary statements  P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P403+P235
HazardClass  IRRITANT
HS Code  2918199890

Methyl 3-hydroxypropanoate Chemical Properties,Uses,Production

General Description

Methyl 3-hydroxypropanoate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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Methyl 3-hydroxypropanoate Spectrum

3-hydroxy-propanoicacidmethylester HOCH2CH2C(O)OCH3 Hydracrylic acid, methyl ester Methyl beta-hydroxypropionate Methyl gamma-hydroxypropionate Methyl hydracrylate Methyl3-hydroxypropionate METHYL 3-HYDROXYPROPANOATE 3-Hydroxypropionic acid methyl ester methyl 3-hydroxypropanoate(SALTDATA: FREE) beta-Hydroxypropionic acid methyl ester propanoic acid, 3-hydroxy-, methyl ester 6149-41-3 6419-41-3 ADVANCED INT.