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(S)-1-N-Boc-2-methylpiperazine

(S)-1-N-Boc-2-methylpiperazine Structure
CAS No.
169447-70-5
Chemical Name:
(S)-1-N-Boc-2-methylpiperazine
Synonyms
tert-butyl (S)-2-methylpiperazine-1-carboxylate;(R)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-1-Boc-2-methl-piperazine;(S)-N-Boc-2-methylpiperazine;(R)-2-METHYL-1-BOC-PIPERAZINE;(S)-1-Boc-2-methyl-piperazine;(S)-N1-BOC-2-METHYLPIPERAZINE;1-Boc-2-(S)-Methyl Piperazine;(S)-1-N-BOC-2-METHYL PIPERAZINE
CBNumber:
CB9714476
Molecular Formula:
C10H20N2O2
Molecular Weight:
200.28
MOL File:
169447-70-5.mol
Modify Date:
2023/12/18 16:59:08

(S)-1-N-Boc-2-methylpiperazine Properties

Melting point 43.0 to 47.0 °C
Boiling point 268.7±15.0 °C(Predicted)
Density 0.997±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
pka 8.49±0.40(Predicted)
color White to Almost white
InChI InChI=1S/C10H20N2O2/c1-8-7-11-5-6-12(8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m0/s1
InChIKey DATRVIMZZZVHMP-QMMMGPOBSA-N
SMILES N1(C(OC(C)(C)C)=O)CCNC[C@@H]1C
CAS DataBase Reference 169447-70-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P271
RIDADR  UN3077
HS Code  2933599590

(S)-1-N-Boc-2-methylpiperazine price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) B4846 (S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine min. 98.0 % 169447-70-5 1G ₹5000 2022-05-26 Buy
TCI Chemicals (India) B4846 (S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine min. 98.0 % 169447-70-5 5G ₹14800 2022-05-26 Buy
Product number Packaging Price Buy
B4846 1G ₹5000 Buy
B4846 5G ₹14800 Buy

(S)-1-N-Boc-2-methylpiperazine Chemical Properties,Uses,Production

Uses

(S)-1-N-Boc-2-methylpiperazine is used in the preparation of pyrazolo[3,4-b]pyridine dual pharmacophores as PDE4-muscarinic antagonists.

Synthesis

A solution of (S)-2-methyl piperazine (2 g, 20 mmol) in THF (200 ml_) was mixed with nBuLi (25 ml, 1.6 M in hexanes, 40 mmol) at rt. The solution was stirred for 30 minutes before TBDMSCI (3.04 g, 20 mmol) was added. The mixture was stirred for 1 hour and then (Boc)2O (5.2 g, 24 mmol) was added to the solution. After 1 hour, the solution was diluted with H2O (50 ml). The organic layer was separated, washed with brine (50 mL), dried over Na2SO4, and concentrated EPO under vacuum. Finally, (S)-1-N-Boc-2-methylpiperazine was obtained after purification.(S)-1-N-Boc-2-methylpiperazine

Global( 256)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Reax Chemicals 08048372701Ext 416 Hyderabad, India 4223 58 Inquiry
Shanghai Boc Chemical Co., Ltd. 021-34975602; +8618721111801 China 138 58 Inquiry
Purest Pharmaceuticl (Xi’an) Co,.LTD +8613893405577 China 74 58 Inquiry
Shanghai UCHEM Inc. +862156762820 +86-13564624040 China 6938 58 Inquiry
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Shenzhen Nexconn Pharmatechs Ltd +86-755-89396905 +86-15013857715 China 10259 58 Inquiry

(S)-1-N-Boc-2-methylpiperazine Spectrum

(R)-2-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-2-METHYL-1-BOC-PIPERAZINE (S)-1-N-BOC-2-METHYL PIPERAZINE (S)-2-METHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (S)-1-Boc-2-methyl-piperazine Tert-Butyl2(S)-methylpiperazine-1-carboxylate 2-S-Methyl-piperazine-1-carboxylic acid tert-butyl ester (S)-1-N-Boc-2-Methylpiperizine tert-butyl 2(S)-methylpiperazine-1-carboxylate (S)-N1-BOC-2-METHYLPIPERAZINE (S)-1-Boc-2-methl-piperazine (S)-1-N-Boc-2-Methylpiperazine ,98% (2S)-2-Methylpiperazine, N1-BOC protected 98% tert-Butyl (2S)-2-methylpiperazine-1-carboxylate (2S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine (2S)-2-Methyl-1-piperazinecarboxylic Acid 1,1-DiMethylethyl Ester tert-Butyl (2S)-2-Methylpiperazine-1-carboxylate 1-Piperazinecarboxylic acid, 2-methyl-, 1,1-dimethylethyl ester, (2S)- (S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine (2S)-2-Methylpiperazine,N1-BOCprotected98% (S)-N-Boc-2-methylpiperazine (S)-N-Boc-2-methylpiperazine,98%e.e. (S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine 1-Boc-2-(S)-Methyl Piperazine TERT-BUTYL (2S)-2-METHYPIPERAZINE-1-CARBOXYLATE (S)-1-(tert-Butoxycarbonyl)-2-methylpiperazine > tert-Butyl (S)-2-Methyl-1-piperazinecarboxylate (S)-2-Methyl-1-piperazinecarboxylic Acid tert-Butyl Ester (S)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE (R)-TERT-BUTYL 2-METHYLPIPERAZINE-1-CARBOXYLATE tert-butyl (S)-2-methylpiperazine-1-carboxylate 169447-70-5 170033-47-4 Chiral Reagents Heterocycles pharmacetical Piperaizine