ベナゼプリル

ベナゼプリル 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

ベナゼプリル MSDS

(3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid

ベナゼプリル 化学特性,用途語,生産方法

効能

血圧降下薬, アンジオテンシン変換酵素(ACE)阻害薬

定義

ChEBI: A benzazepine that is benazeprilat in which the carboxy group of the 2-amino-4-phenylbutanoic acid moiety has been converted to the corresponding ethyl ester. It is used (generally as its hydrochloride salt) as a prodrug for the angiotensin-converting enzy e inhibitor benazeprilat in the treatment of hypertension and heart failure.

酵素阻害剤

This ACE-directed pro-drug (FWfree-acid = 424.50 g/mol; CAS 86541-75-5), also known as 3-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-2,3,4,5- tetrahydro-2-oxo-(S-(R*,R*))-1H-1-benzazepine-1-acetic acid, Lotensin and CGS 14824A, is rapidly metabolized to its diacid benazeprilat (CGS 14831; FWfree-diacid = 396.44 g/mol), the latter a potent, long-acting inhibitor of peptidyl-dipeptidase A, or angiotensin I-converting enzyme, IC50 = 1.7 nM. Lotensin is used to treat hypertension, congestive heart failure, and chronic renal failure. The antihypertensive effects of benazepril begin as early as 30 min after a single dose, and those effects during consecutive dosing are also sustained for 24 h with a lesser diurnal variation in blood pressure

ベナゼプリル 上流と下流の製品情報

原材料

準備製品

ベナゼプリル 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Jiangxi Huihe Chemical Co., Ltd.	+86-19189228086 +8618858568638	wuzhouding@huihecrop.com	China	886	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29885	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8618959220845	sales@amoychem.com	China	6383	58
Chongqing Chemdad Co., Ltd	+86-023-6139-8061 +86-86-13650506873	sales@chemdad.com	China	39894	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
Shandong Hengshannuode Pharmaceutical Technology Co., Ltd.	+8615065888978	admin@hsnordpharma.com	China	92	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32038	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	7724	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15361	58

86541-75-5(ベナゼプリル)キーワード:

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• 86541-75-5
• 2-[(4s)-4-[[(1s)-1-ethoxycarbonyl-3-phenyl-propyl]amino]-5-oxo-6-azabicyclo[5.4.0]undeca-7,9,11-trien-6-yl]acetic acid
• genazepril
• BENAZEPRIL HCL, RELATED COMPOUND B(3S)-3-[[(1R)-1-(ETHOXYCARBONYL)-3-PHENYLPROPYL]AMINO]-2,3,4,5-TETRAHYDRO-2-OXO-1H-1-BENAZAPINE-1-ACETIC ACID, MONOHYDROCHLORIDE USP STANDARD
• BENAZEPRIL HCL, MM(CRM STANDARD)
• BENAZEPRIL HCL, USP STANDARD
• BENAZEPRIL HCL USP(CRM STANDARD)
• BENAZEPRIL MM
• BENAZEPRIL MM(CRM STANDARD)
• BENAZEPRIL FREE BASE
• BENAZCPRIL
• 1H-1-Benzazepine-1-acetic acid, 3-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, (3S)-
• 1H-1-Benzazepine-1-acetic acid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, [S-(R*,R*)]-
• Benapril
• Briem
• Cibacen WS
• Cibacene
• (3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid
• [S-(R^<*>^，R^<*>^)]-3-[[1- (Ethoxycarbonyl)-3-phenylpropyl]amino]-2，3，4，5-tetrahydro-2-oxo-lH-1-benzazepine-1-acetic acid
• Cibacene：Lotensin
• 2-[(4S)-4-[[(1S)-1-ethoxycarbonyl-3-phenyl-propyl]amino]-3-oxo-2-azabicyclo[5.4.0]undeca-7,9,11-trien-2-yl]acetic acid
• (3S)-3-[[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid
• 2-[(3S)-3-[[(1S)-1-Ethoxycarbonyl-3-phenylpropyl]amino]-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-1-yl]acetic acid
• Cibcen WS
• Benazepril
• Benazapril
• 2-[(3S)-3-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]aMino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
• 2-[(3S)-3-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid
• Benazepril USP/EP/BP
• 2-((S)-3-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetic acid
• Bifeprunox Impurity 16
• ベナゼプリル
• (2S)-4-フェニル-2-[[[(3S)-2,3,4,5-テトラヒドロ-2-オキソ-1-(ヒドロキシカルボニルメチル)-1H-1-ベンゾアゼピン]-3-イル]アミノ]酪酸エチル
• ベナプリル
• チバセンWS
• (3S)-3-[[(S)-1-(エトキシカルボニル)-3-フェニルプロピル]アミノ]-2,3,4,5-テトラヒドロ-2-オキソ-1H-1-ベンゾアゼピン-1-酢酸
• (3S)-3-[[(1S)-1-(エトキシカルボニル)-3-フェニルプロピル]アミノ]-2,3,4,5-テトラヒドロ-2-オキソ-1H-1-ベンゾアゼピン-1-酢酸
• 2-[(3S)-3-[[(1S)-1-エトキシカルボニル-3-フェニルプロピル]アミノ]-2-オキソ-2,3,4,5-テトラヒドロ-1H-1-ベンゾアゼピン-1-イル]酢酸
• 2-[(3S)-3-{[(2S)-1-エトキシ-1-オキソ-4-フェニルブタン-2-イル]アミノ}-2-オキソ-2,3,4,5-テトラヒドロ-1H-1-ベンゾアゼピン-1-イル]酢酸
• アンギオテンシン変換酵素阻害剤