바트라코톡신
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바트라코톡신 속성
- 알파
- 24584 -5 To -10°; 24300 -260° (c = 0.23 in methanol)
- 끓는 점
- 614.87°C (rough estimate)
- 밀도
- 1.1575 (rough estimate)
- 굴절률
- 1.5800 (estimate)
- 저장 조건
- Store at -20°C
- 산도 계수 (pKa)
- 7.45(at 25℃)
- 물리적 상태
- 필름같은 재질
- 색상
- 결정체가 아님
- CAS 데이터베이스
- 23509-16-2
안전
유엔번호(UN No.) | 3172 | ||
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위험 등급 | 6.1(b) | ||
포장분류 | III | ||
유해 물질 데이터 | 23509-16-2(Hazardous Substances Data) | ||
독성 | LD50 s.c. in mice: 2 mg/kg (Tokuyama) |
바트라코톡신 C화학적 특성, 용도, 생산
화학적 성질
Noncrystal.위험도
Extremely toxic; deadly poison; neurotoxic; cardiotoxic activity; bara-chotoxin that blocks neuromuscular transmission; respiratory paralysis; death.생물학적 활성
Potent neurotoxin that activates voltage-gated sodium channels. Shifts voltage-dependent activation to more negative potentials, inactivation is disabled and pore conductance and selectivity are altered (displays increased permeability for NH 4 + , K + and Cs + ions).Safety Profile
A deadly poison byintraperitoneal, intravenous, and subcutaneous routes.When heated to decomposition it emits toxic fumes ofNOx.효소 저해제
This lipid-soluble neurotoxin (FW = 526.67 g/mol; CAS 23509-16-2; LD50 = ~2 μg/kg mouse body weight.), isolated from the skin of the Columbian poison-dart frog Phyllobates aurotaenis, enhances Na+ conductance, promoting opening of voltage-gated Na+ channels, inducing depolarization of the resting membrane potential. It does so by binding to the sodium channel, keeping the membrane permeable to sodium ions in an all-or-none manner. This results in hyperexcitability of excitable tissues, followed by convulsions, paralysis, and death in animals. The most common use of batrachotoxin is in darts for bloguns used in hunting by the Noanamá Chocó and Emberá Chocó Indians of western Colombia. Batrachotoxin has also been identified in the feathers of the passerine birds of New Guinea Pitohui dichrous, Pitohui kirhocephalus, and Ifrita kowaldi. The less toxic batrachotoxin A is the deesterified steroid.바트라코톡신 준비 용품 및 원자재
원자재
준비 용품
바트라코톡신 공급 업체
글로벌( 8)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 |
Ethan@dornechem.com | China | 3126 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 |
info@gihichemicals.com | China | 50003 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
바트라코톡신 관련 검색:
베타-테르핀올
Tetracaine hydrochloride
Aconitine
VERATRIDINE
TETRODOTOXIN
QX-314
L-KAWAIN
PD 85639
(+)-ISOPULEGOL
DIHYDROCARVEOL
(-)-DIHYDROCARVEOL
2,5-DIMETHYL-1,5-HEXADIEN-3-OL
BATRACHOTOXIN
CIS-2-AMINOMETHYL-1-METHYL-CYCLOHEXANOL
1-ALLYL-1-METHOXY-CYCLOHEXANE
homobatrachotoxin
(E)-4-ETHOXY-NONA-1,5-DIENE
2-METHOXY-2-METHYL-BUT-3-EN-1-OL