2-페닐페놀
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2-페닐페놀 속성
- 녹는점
- 57-59 °C(lit.)
- 끓는 점
- 282 °C(lit.)
- 밀도
- 1.21
- 증기압
- 7 mm Hg ( 140 °C)
- 굴절률
- 1.6188 (estimate)
- 인화점
- 255 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 에탄올, 아세톤, 벤젠, 수산화 나트륨, 클로로포름, 아세토니트릴, 톨루엔, 헥산, 리그로인, 에틸 에테르, 피리딘, 에틸렌 글리콜, 이소프로판올, 글리콜 에테르 및 폴리글리콜에 용해됩니다.
- 물리적 상태
- 플레이크 크리스탈
- 산도 계수 (pKa)
- 10.01(at 25℃)
- 색상
- 하얀색
- 수소이온지수(pH)
- 7 (0.1g/l, H2O, 20℃)
- 냄새
- 흰색 또는 밝은 노란색 크리스탈, 온화한 숯. 달콤한 냄새
- 폭발한계
- 1.4-9.5%(V)
- 수용성
- 0.7g/L(20℃)
- 감도
- Hygroscopic
- Merck
- 14,7304
- JECFA Number
- 735
- BRN
- 606907
- 안정성
- 안정적인. 타기 쉬운. 강한 산화제, 할로겐과 호환되지 않습니다.
- InChIKey
- LLEMOWNGBBNAJR-UHFFFAOYSA-N
- LogP
- 3.18 at 22.5℃
- CAS 데이터베이스
- 90-43-7(CAS DataBase Reference)
- IARC
- 3 (Vol. 73) 1999
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi,N | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38-50-37/38/50-36 | ||
안전지침서 | 22-61 | ||
유엔번호(UN No.) | UN 3077 9/PG 3 | ||
WGK 독일 | 2 | ||
RTECS 번호 | DV5775000 | ||
자연 발화 온도 | >520 °C | ||
TSCA | Yes | ||
위험 등급 | 9 | ||
포장분류 | III | ||
HS 번호 | 29071900 | ||
유해 물질 데이터 | 90-43-7(Hazardous Substances Data) | ||
독성 | LD50 orally in rats: 2.48 g/kg (Hodge) | ||
기존화학 물질 | KE-02870 |
2-페닐페놀 C화학적 특성, 용도, 생산
개요
2-phenylphenol(OPP) is a broad spectrum fungicide used to protect crops in storage. It is highly soluble in water, moderately voatile but is not expected to be persistent in the environment. OPP is more selective than other free phenols but does produce phytotoxic effects.화학적 성질
o-Phenylphenol is a white to buff-colored crystalline solid with a distinct odor. When heated to decomposition, it emits acrid smoke and irritating fumes.용도
2-Phenylphenol is a agriculture fungicide and is no longer used as a food additive.생산 방법
OPP is produced as a by-product in the manufacture of diphenyl oxide or by aldol condensation of hexazinone.정의
ChEBI: 2-Phenylphenol is a member of the class of hydroxybiphenyls that is biphenyl substituted by a hydroxy group at position 2. It is generally used as a post-harvest fungicide for citrus fruits. It has a role as an environmental food contaminant and an antifungal agrochemical. It derives from a hydride of a biphenyl.제조 방법
2-Phenylphenol can be recovered from the distillation residue of the process of phenol production via sulfonation. The phenol distillation residue contains about 40% of phenyl phenol with the other components including phenol, inorganic salts, water and so on. After vacuum distillation, the mixed phenyl phenol fraction is separated out with the vacuum being 53.3-66.7kPa. The temperature, started to be cut at 65-75 ℃ to until 100 ℃ above, but should not higher than 1345 ℃. Then take advantage of the solubility difference of ortho, p-hydroxy biphenyl in the trichlorethylene, the two are separated into pure product. The mixed material (mainly 2-hydroxy biphenyl and 4-hydroxy biphenyl) is heated to be dissolved in the trichlorethylene, after cooling, first precipitate out 4-hydroxy biphenyl crystal. After centrifuge filtration, dry to obtain 4-hydroxy biphenyl. The mother liquor was washed with a sodium carbonate solution, followed by dilute alkaline to make the 2-hydroxybiphenyl salt. After standing stratification, take the upper 2-hydroxybiphenyl sodium salt for dehydration under reduced pressure, namely, sodium salt products. The 2-hydroxybiphenylsodium salt is white to light red powder, being easily soluble in water with the solubility in 100g of water being 122g. The pH value of the 2% aqueous solution is 11.1-12.2. It is also easily soluble in acetone, methanol, soluble in glycerol, but insoluble in oil. The sodium salt of 2-hydroxy biphenyl, after acidification, can lead to the formation of 2-hydroxy biphenyl with both of them being food additives.주요 응용
2-phenylphenol is remarkably versatile organic chemical products, widely used antiseptic, auxiliaries and surfactant synthesis of new plastics, resins and polymer materials in areas such as stabilizers and flame retardants. It is used for the post-harvest control of storage diseases of apples, citrus fruit, stone fruit, tomatoes, cucumbers and other vegetables. It is also used for the protection of textiles and timber and as a fungistat in water-soluble paints.일반 설명
Light lavender crystals or solid.공기와 물의 반응
Insoluble in water.반응 프로필
2-Phenylphenol react as a weak organic acid. Exothermically neutralizes bases. May react with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides to generate flammable gas (H2) and the heat of the reaction may ignite the gas. Is sulfonated very readily (for example, by concentrated sulfuric acid at room temperature) in exothermic reactions. May be nitrated very rapidly. Nitrated phenols often explode when heated and also form metal salts that tend toward detonation by rather mild shock. Can react with oxidizing agents .화재위험
2-Phenylphenol is combustible.농업용
Fungicide, Disinfectant, Microbiocide: Used to make fungicides. Also used to make dye stuffs and rubber chemicals, but used primarily as a disinfectant cleaner. Registered for use in the U.S. and U.K.상품명
ANTHRAPOLE 73®; DOWCIDE-1®; Invalon OP®; KIWI LUSTR-277®; NECTRYL®; PREVENTOL-O Extra®; REMOL TRF®; TETROSIN OE®; TETROSIN OE-N®; TORSITE®; TUMESCAL OPE®Safety Profile
A poison by intraperitoneal route.Moderately toxic by ingestion and possibly other routes.An experimental teratogen. Other experimentalreproductive effects. Human mutation data reported.Severe eye and moderate skin irritant. Questionablecarcinogen wi잠재적 노출
o-Phenylphenol is used in the manufacture of plastics, resins, rubber, as Agricultural chemical, in making fungicides; as an intermediate in making dye stuffs and rubber chemicals; a germicide; used in food packaging.Carcinogenicity
IARC classified SOPP as a B2 carcinogen in 1983, based on reports from Japan that high dietary levels of this sodium salt caused bladder tumors in male rats. Both sodium saccharin and sodium cyclamate also cause bladder tumors at high doses in male rats, but classification of these food additives as B2 carcinogens was recently rescinded by IARC at a meeting in 1998.The U.S. National Toxicology Program conducted a skin painting study with OPP in groups of 50 mice per sex. The OPP was applied as an acetone solution on 3 days per week for 2 years, both alone and as a promoter with DMBA. No skin neoplasms were observed in either sex treated with OPP alone, and there were no tumor enhancing or inhibiting effects when OPP and DMBA were given in combination.
신진 대사 경로
2-Phenylphenol is not used on growing plants because it is too phytotoxic and there appears to be no information published on its metabolism in plants. Its widespread use as a preservative, disinfectant and fungistat on stored food (either by direct application or impregnated in packaging) requires studies on its environmental fate and metabolism in mammals. Several studies in mammals are available and the compound has been the subject of an evaluation by the UK MAFF Pesticide Safety Directorate (PSD); the results have been published (PSD, 1993). This evaluation was prompted by the discovery of bladder tumours in rats treated with high doses of the compound.2-Phenylphenol is also used as the sodium and potassium salts where water solublity is important. No information is available specifically on the latter. The metabolism of the free phenol and the sodium salt have been studied separately. Once absorbed into a cell, provided that internal pH control is maintained, the two forms should be indistinguishable.
운송 방법
UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name RequiredPurification Methods
Crystallise it from pet ether. [Beilstein 6 IV 4579.]Toxicity evaluation
2-phenylphenol has a moderate to low toxicity to biodiversity. This substance has a low oral mammalian toxicity, is carcinogenic, a neurotoxin and recognised irritant. 2-Phenylphenol and its sodium salt have a low acute toxicity in mammals when administered orally, with LD50 values ranging from 600 to 3500 mg/kg of body weight.http://sitem.herts.ac.uk/aeru/ppdb/en/Reports/1340.htm
Degradation
2-Phenylphenol is readily degraded in surface waters and municipal waste mixtures, and the degradation is biologically mediated. In river water, radiolabelled 2- phenylphenol at concentrations ranging from 1.2 to 120 μg/litre was degraded to about 50% of the initial concentration in 1 week. The addition of mercuric chloride to inhibit biological activity reduced the decrease to only 10% after 30 days. In activated sludge, radiolabelled 2-phenylphenol at 9.6 mg/litre was degraded to 50% of the initial concentration in 24 h. 2-Phenylphenol therefore meets the criteria to be classified as readily biodegradable (FAO/WHO, 1999).비 호환성
Strong bases, strong oxidizers폐기물 처리
In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.2-페닐페놀 준비 용품 및 원자재
원자재
준비 용품
2-페닐페놀 공급 업체
글로벌( 372)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Fengmu Trading Co., Ltd. | +8613393234347 |
Lyla@fengmuchem.com | China | 2982 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8822 | 58 |
Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 |
daisy@crovellbio.com | China | 5828 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20294 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 16914 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Dalian Richfortune Chemicals Co., Ltd | 0411-84820922 8613904096939 |
sales@richfortunechem.com | China | 304 | 57 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2989 | 55 |