3-Bromopropylamine hydrobromide is used as pharmaceutical raw materials and intermediates. Homotaurine is synthesized from 3-bromopropylamine hydrobromide.
Synthesis
Add the mixture of 3-amino-1-propanol (1ml, 13.3mmol) and 48% HBr (10ml, 40mmol) into the round-bottomed flask and reflux for 15h. Water and HBr were then distilled from the mixture under vacuum. The mixture was further dried under vacuum through a KOH/CaCl column to give 3-Bromopropylamine hydrobromide (2.95 g, 100%) as a brown solid.
