4-시아노피린딘
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4-시아노피린딘 속성
- 녹는점
- 76-79 °C(lit.)
- 끓는 점
- 196 °C
- 밀도
- 1.1145 (rough estimate)
- 증기압
- 41.9Pa at 25℃
- 굴절률
- 1.5242 (estimate)
- 인화점
- 88 °C
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- 40g/L
- 물리적 상태
- 결정 또는 분말
- 산도 계수 (pKa)
- pK1:1.90(+1) (25°C)
- 색상
- 흰색에서 황백색까지
- 수용성
- 3.2 g/100ml (16.4 ºC)
- BRN
- 107712
- 노출 한도
- NIOSH: IDLH 25 mg/m3
- 안정성
- 안정적인. 강염기, 강산화제, 강산과 호환되지 않습니다.
- InChIKey
- GPHQHTOMRSGBNZ-UHFFFAOYSA-N
- LogP
- 0.46 at 25℃
- CAS 데이터베이스
- 100-48-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
위험품 표기 | Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 20/21/22 | ||
안전지침서 | 36/37-24/25 | ||
유엔번호(UN No.) | 3276 | ||
WGK 독일 | 3 | ||
TSCA | Yes | ||
포장분류 | III | ||
HS 번호 | 29333999 | ||
기존화학 물질 | KE-29933 |
4-시아노피린딘 C화학적 특성, 용도, 생산
화학적 성질
beige solid용도
4-Cyanopyridine is used as an intermediate in organic synthesis and pharmaceutical substances like isonicotinylhydrazide, which is used in the treatment of tuberculosis. It is used as a precursor for the preparation of isonicotinic acid and 4-diemthylaminopyridine (DMAP). It is involved in the synthesis of 6-methyl-2-pyridin-4-yl-pyrimidin-4-ylamine by reacting with acetonitrile.Synthesis
4-Cyanopyridine is synthesised by the reaction of 4-methylpyridine with ammonia and air in the presence of a catalyst. The specific synthesis steps are as follows:4-Methylpyridine and ammonia vaporisation preheating to 180-330°C, then into the mixing tank and air mixing uniformly, into the fixed-bed reactor by the top of the fixed-bed reactor after the distribution of the catalyst-filled reactor, the control of the reaction temperature in the range of 330-450 ° C, the reaction head pressure is controlled in the range of 0.020-0.070 KPa, the reaction temperature is controlled by molten salts, the reaction gas after the end of the reaction After the reaction, the reaction gas was condensed to sub-zero fractionation to obtain the crude product of 4-cyanopyridine, and the crude product was distilled to obtain the finished product of 4-cyanopyridine. The conversion rate of 4-methylpyridine was above 99%, and the yield of 4-cyanopyridine was above 98%.
잠재적 노출
Limits in Air NIOSH IDLH525 mg/m3 NIOSH REL: (nitriles) 2 ppm, Ceiling Concentration, not to be exceeded in any 15-minute work period.운송 방법
UN3276 Nitriles, liquid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required, Potential Inhalation Hazard (Special Provision 5).비 호환성
Oxidizing agents, such as perchlorates, peroxides, and permanganates. Nitriles may polymerize in the presence of metals and some metal compounds. They are incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions. Nitriles are generally incompatible with other oxidizing agents such as peroxides and epoxides. The combination of bases and nitriles can produce hydrogen cyanide. Nitriles are hydrolyzed in both aqueous acid and base to give car- boxylic acids (or salts of carboxylic acids). These reactions generate heat. Peroxides convert nitriles to amides. Nitriles can react vigorously with reducing agents. Acetonitrile and propionitrile are soluble in water, but nitriles higher than propionitrile have low aqueous solubility. They are also insoluble in aqueous acids .4-시아노피린딘 준비 용품 및 원자재
원자재
준비 용품
4-AMINOMETHYL-PYRIDINE-2-CARBOXYLIC ACID
2-TERT-BUTYLPYRIDINE-4-CARBONITRILE
2-tert-Butylpyridine-4-carboxylic acid ,97%
4-피리딜아미독심
3-Chloro-4-cyanopyridine
4-[(TERT-BUTOXYCARBONYLAMINO)METHYL]-2-CYANOPYRIDINE
피콜리아민
4-(BOC-AMINOMETHYL)PYRIDINE-2-CARBOXYLIC ACID
2,4-피리딘디카보니트릴
4-AMIDINOPYRIDINIUM CHLORIDE
4-(BOC-AMINOMETHYL)PYRIDINE
4-CYANOPYRIDIN-3-일보론산
4-(4-CHLOROBENZOYL)PYRIDINE
부틸피리딘(4-3차)
피콜리아민
4-PYRIDINECARBOXAMIDINE
4-피리딘 메탄올
Ethyl isonicotinate
2,3,5,6-TETRAFLUORO-4-PYRIDINE-CARBONITRILE
4-시아노피린딘 공급 업체
글로벌( 576)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
Junwee Chemical co., Ltd. | +86-571-85808636 +86-13958122542 |
sales@junweechem.com | China | 821 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12495 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20291 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 |
sales@frappschem.com | China | 885 | 50 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21663 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 967 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10311 | 58 |
4-시아노피린딘 관련 검색:
2,6-피리딘디카보니트릴 2-시아노피린딘 시안초산 메틸렌 티오사이아네이트 에틸 시아노아크릴산 나트륨 사이아노브로민하이드라이드(나트륨 시아노브롬하이드리드) 3,4-피리딘디카보니트릴 3-시아노피린딘 니코틴산 1-에틸-1,2-디하이드로-6-하이드록시-4-메틸-2-옥소-3-피리딘카복사마이드 2,4-피리딘디카보니트릴 4-시아노피린딘
2-Chloro-3-cyanopyridine
Ethyl N-cyanoethanimideate
2-Pyridinecarboxaldehyde
3-Pyridinecarboxaldehyde
3,4-Pyridinedicarboxylic acid
Isonicotinic acid