베타-알라닌
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베타-알라닌 속성
- 녹는점
- 202 °C (dec.)(lit.)
- 끓는 점
- 237.1±23.0 °C(Predicted)
- 밀도
- 1,437 g/cm3
- 굴절률
- 1.4650 (estimate)
- FEMA
- 3252 | BETA-ALANINE
- 인화점
- 204-206°C
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- H2O: 1 M at 20 °C, 투명, 무색
- 산도 계수 (pKa)
- 3.55(at 25℃)
- 물리적 상태
- 결정성 분말
- 색상
- 하얀색
- 수소이온지수(pH)
- 6.0-7.5
- 냄새
- 100.00%에서. 냄새 없는
- ?? ??
- 냄새 없는
- 수용성
- 물에 용해됨(550g/L). 알코올에 약간 용해됩니다. 에테르와 아세톤에 불용성.
- 분해온도
- 204-206 ºC
- 최대 파장(λmax)
- λ: 260 nm Amax: ≤0.02
λ: 280 nm Amax: ≤0.02
- JECFA Number
- 1418
- Merck
- 14,205
- BRN
- 906793
- 안정성
- 안정적인. 건조한 상태로 유지하세요.
- InChIKey
- UCMIRNVEIXFBKS-UHFFFAOYSA-N
- LogP
- -0.882 (est)
- CAS 데이터베이스
- 107-95-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38 | ||
안전지침서 | 24/25-36-26 | ||
WGK 독일 | 3 | ||
RTECS 번호 | UA2369200 | ||
TSCA | Yes | ||
HS 번호 | 29224920 | ||
기존화학 물질 | KE-00283 |
베타-알라닌 C화학적 특성, 용도, 생산
개요
β-Alanine (or beta-alanine) is a naturally occurring beta amino acid, which is an amino acid in which the amino group is at the β- position from the carboxylate group (i.e., two atoms away. The IUPAC name for β-alanine is 3-amino propanoic acid. Unlike its counterpart α-alanine, β-alanine has no stereocenter.β-Alanine is not used in the biosynthesis of any major proteins or enzymes. It is formed in vivo by the degradation of dihydrouracil and carnosine. It is a component of the naturally occurring peptides carnosine and anserine and also of pantothenic acid (vitamin B5), which itself is a component of coenzyme A. Under normal conditions, β-alanine is metabolized into acetic acid.
β-Alanine is the rate-limiting precursor of carnosine, which is to say carnosine levels are limited by the amount of available β-alanine. Supplementation with β-alanine has been shown to increase the concentration of carnosine in muscles, decrease fatigue in athletes and increase total muscular work done.
Typically, studies have used supplementing strategies of multiple doses of 400 mg or 800 mg, administered at regular intervals for up to eight hours, over periods ranging from 4 to 10 weeks . After a 10 - week supplementing strategy, the reported increase in intramuscular carnosine content was an average of 80.1% (range 18 to 205%).
화학적 성질
This is a secondary amino acid, which is formed in vivo by the degradation of dihydrouracil and carnosine. Because neuronal uptake and neuronal receptor sensitivity to β-alanine have been demonstrated, the compound may be a false transmitter replacing GABA. A rare genetic disorder, hyper-β-alaninemia, has been reported. It is used as a flavor enhancer, flavoring agent, nutrient supplement or adjuvant. β-Alanine has a slightly sweet taste.출처
Reported to occur as a component in amino acids; carnosine, anserine, pantothenic acid용도
β-Alanine is a naturally occurring beta amino acid. β-Alanine is formed in vivo by the degradation of dihydrouracil (D449990) and carnosine. β-Alanine is also the rate-limiting precursor of carnosine, as a result supplementation with β-alanine increases the concentration of carnosine in muscles.정의
ChEBI: A naturally-occurring beta-amino acid comprising propionic acid with the amino group in the 3-position.제조 방법
By heating acrylic acid with concentrated aqueous ammonia under pressure, by addition of acrylonitrile to phthalimide or to ammonia; from β-aminopropionitrile, from succinimide by the Hofmann degradation.일반 설명
An N-blocked form of alanine.Purification Methods
Crystallise β-alanine by dissolving it in a hot saturated aqueous solution, filtering, adding four volumes of absolute EtOH and cooling in an ice-bath. Recrystallise it in the same way and then finally, crystallise it from a warm saturated solution in 50% EtOH and adding four volumes of absolute EtOH with cooling in an ice-bath. The crystals are dried in a vacuum desiccator over P2O5. [Donovan & Kegeles J Am Chem Soc 83 255 1961, Beilstein 4 IV 2526.]베타-알라닌 준비 용품 및 원자재
원자재
준비 용품
N-T-BOC-Β-ALANINE
칼슘디베타알라니네이트
N-말레오일-β-알라닌
(+/-)-펜토텐 산, 칼슘 염 모노수화물
H-BETA-ALA-OTBU HCL
3-ISOPROPYLAMINO-PROPIONIC ACID ETHYL ESTER X HCL >98%
벤프라캅
판토텐산칼슘
2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide
L-알라닌
PENTAGASTRIN
5-CHLORO-1H-INDAZOLE-3-CARBOXYLIC ACID
Disperse Blue 148
Pamidronic acid
N-hydroxyethyl-N-hydroxyalkyl-β-alanine
N-(tert-Butoxycarbonyl)-4-piperidone
에틸3-(클로로설파닐-프로판-2-일-아미노)프로파노에이트
판토텐산
3-아미노프로판알
베타-알라닌 공급 업체
글로벌( 869)공급 업체
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