3-인돌프로피온산
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3-인돌프로피온산 속성
- 녹는점
- ~133 °C
- 끓는 점
- 82 °C(lit.)
- 밀도
- 0.960 g/mL at 20 °C
- 증기 밀도
- 2.1 (vs air)
- 증기압
- 33 mm Hg ( 20 °C)
- 굴절률
- n
20/D 1.377(lit.)
- 인화점
- 53 °F
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- 에탄올: 용해성50mg/mL, 투명, 노란색~주황색
- 산도 계수 (pKa)
- 4.77±0.10(Predicted)
- 물리적 상태
- 수정 같은
- 색상
- 연노랑
- 수용성
- 약간 용해됨
- BRN
- 147733
- CAS 데이터베이스
- 830-96-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 22-36/37/38 | ||
안전지침서 | 26-37/39 | ||
WGK 독일 | 3 | ||
RTECS 번호 | NM1329000 | ||
F 고인화성물질 | 8-10-23 | ||
TSCA | Yes | ||
HS 번호 | 29339990 | ||
독성 | LDLo intraperitoneal in mouse: 100mg/kg |
3-인돌프로피온산 C화학적 특성, 용도, 생산
개요
Indole-3-propionic acid is a bacterial metabolite that has antioxidant and neuroprotective activities. It scavenges ABTS radicals in a cell-free assay when used at concentrations ranging from 50 to 150 μM and decreases hydrogen peroxide-induced malondialdehyde (MDA) levels in rat striatal membranes (IC50 = 180 μM). Indole-3-propionic acid also decreases increases in MDA levels induced by amyloid β (1-42) in PC12 cells. It decreases ischemia-induced increases in cell death of pyramidal neurons and levels of 4-hydroxy nonenal (HNE; ) and glial fibrillary acidic protein (GFAP) in the hippocampal CA1 region in gerbils when administered at a dose of 10 mg/kg per day.화학적 성질
pale yellow to yellow crystalline powder용도
3-Indolepropionic acid is a deamination product of Tryptophan (T947200) that protects the hippocampus (studied in gerbils) from ischemic damage and oxidative stress. It’s ability to protect the neurons in this way is attributed to its potent antioxidative effects. 3-Indolepropionic acid is also hypothesized to have protective effects on the thyroid gland.정의
ChEBI: An indol-3-yl carboxylic acid that is propionic acid substituted by a 1H-indol-3-yl group at position 3.일반 설명
3-Indolepropionic acid is an effective inhibitor of aggregation of misfolded β-amyloid protein (Abeta). Three-component one-pot procedure has been reported to assemble 3-indolepropionic acids.Purification Methods
Recrystallise it from EtOH/water [James & Ware J Phys Chem 89 5450 1985]. The picrate has m 143-144o, and the methyl ester crystallises from *C6H6 or MeOH with m 81-83o. [Beilstein 22 III/IV 1113, 22/3 V 114.]3-인돌프로피온산 준비 용품 및 원자재
원자재
Ethyl 2-oxocyclopentanecarboxylate
디카복실산, C4-6
weak
인돌-2-카르복실산
phenylhydrazone
1H-Indole-3-propanoic acid, 1-(2,2-dimethyl-1-oxopropyl)-
2-(1H-indol-3-yl)butanedioic acid
1H-Indole-3-propanoic acid, β-oxo-
Diethyl 2-(1H-indol-3-ylmethyl)propanedioate
Propanedioic acid,2-(1H-indol-3-ylmethyl)-
3-(2-카르복시인돌-3-일)프로피온산
1H-Indole-3-propanoicacid, cyclohexyl ester
1H-인돌-3-아세트산,.알파.-메틸-
DONAXINE iodomethylate
3-(2-BROMOETHYL)INDOLE
5-Bromoindole
준비 용품
3-인돌프로피온산 공급 업체
글로벌( 684)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12450 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29894 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8822 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |