(S)-α-(Hydroxymethyl)benzeneacetic acid (1β,2α,4α,5β,7α)-9-butyl-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane-7-yl ester C화학적 특성, 용도, 생산
Originator
Butylscopolamine,China Pharm
Manufacturing Process
1300 g of scopolamine base and 350 g of n-butylbromide in 600 ml
acetonitrile is heated at 65°C for 160 hours. The oil obtained is dissolved in
methanol. The solution is cooled and crystalline scopolamine N-n-butylbromide
is filtered. After recrystallization from methanol was obtained scopolamine N-n-butylbromide with melting point 142-144°C and [α]d
20 = -20.5° (3%
solution in water); yield 65%.
Therapeutic Function
Anticholinergic, Spasmolytic, Antitussive
(S)-α-(Hydroxymethyl)benzeneacetic acid (1β,2α,4α,5β,7α)-9-butyl-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane-7-yl ester 준비 용품 및 원자재