브롬화부틸
|
|
브롬화부틸 속성
- 녹는점
- -112 °C
- 끓는 점
- 100-104 °C(lit.)
- 밀도
- 1.276 g/mL at 25 °C(lit.)
- 증기 밀도
- 4.7 (vs air)
- 증기압
- 150 mm Hg ( 50 °C)
- 굴절률
- n
20/D 1.439(lit.)
- 인화점
- 23 °C
- 저장 조건
- Store below +30°C.
- 용해도
- 0.6g/L
- 물리적 상태
- 액체
- 색상
- 무색투명~연황색
- 냄새
- 특유의 냄새
- 폭발한계
- 2.8-6.6%, 100°F
- 수용성
- 0.608g/L(30℃)
- Merck
- 14,1553
- BRN
- 1098260
- Dielectric constant
- 7.1600000000000001
- 안정성
- 안정적인. 가연성 - 인화점이 낮습니다. 강한 산화제, 강한 염기와 호환되지 않습니다.
- InChIKey
- MPPPKRYCTPRNTB-UHFFFAOYSA-N
- LogP
- 2.75
- CAS 데이터베이스
- 109-65-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | F,Xi,N | ||
---|---|---|---|
위험 카페고리 넘버 | 11-36/37/38-51/53-10 | ||
안전지침서 | 16-26-60-37/39 | ||
유엔번호(UN No.) | UN 1126 3/PG 2 | ||
WGK 독일 | 2 | ||
RTECS 번호 | EJ6225000 | ||
자연 발화 온도 | 509 °F | ||
TSCA | Yes | ||
위험 등급 | 3 | ||
포장분류 | II | ||
HS 번호 | 29033036 | ||
유해 물질 데이터 | 109-65-9(Hazardous Substances Data) | ||
독성 | LD50 orally in Rabbit: 2761 mg/kg |
브롬화부틸 C화학적 특성, 용도, 생산
화학적 성질
1-bromobutane appears as a clear colorless to slightly yellow liquid with aroma. Flash point 65°F. Denser than water and insoluble in water, soluble in organic solvents such as alcohol, ether and chloroform.Vapors heavier than air.용도
1-Bromobutane is used as an intermediate in organic synthesis and as a solvent for cleaning and degreasing. It acts as an alkylating agent as well as to prepare organometallic compounds such as n-butyllithium. It is also involved in the synthesis of procaine and tetracaine. It reacts with magnesium metal to prepare the Grignard reagent, which is used to form carbon-carbon bonds.주요 응용
1-Bromobutane may be used as a derivatization reagent for multiple functional groups (amino, carboxyl, and phenolic hydroxyl groups) of amino acids to improve hydrophobicities and basicities of the amino acids. It may also be used as an internal standard for the quantification of 1- and 2-bromopropane in human urine by headspace gas chromatography.일반 설명
1-Bromobutane, an alkyl halide, is an alkylating agent. Its rotational constants, nuclear quadrupole constants and centrifugal distortion constants have been stated based on microwave spectral data. The rate coefficient for the reaction of 1-bromobutane with hydrogen atoms has been reported to be 2.4±1.2x1010cm3mol-1s-1.공기와 물의 반응
Highly flammable. Insoluble in water.반응 프로필
1-Bromobutane is incompatible with strong bases and oxidizers [USCG, 1999].위험도
Flammable, dangerous fire risk.건강위험
Irritating to the eyes, nose, throat, and upper respiratory tract. Symptoms of exposure include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting. Irritating to the skin.Safety Profile
Moderately toxic by intraperitoneal route. Mddly toxic by inhalation. Dangerous fire hazard when exposed to heat, flame, or oxidizers. Violent reaction with bromobenzene + sodium above 30℃. Can react with oxidizing materials. To fight fire, use CO2, dry chemical, mist or spray. See also BROMIDES.Synthesis
1-bromobutane is a primary alkyl halide (primary alkyl) and therefore it is produced from bimolecular nucleophilic substitution reactions (Sn2).The preparation method of 1-bromobutane is as follows: stirring n-butanol, sodium bromide, water and sulfuric acid evenly, heating under reflux for 3 hours, steaming out the crude bromobutane, washing with water, treating with cold concentrated sulfuric acid, and distilling to obtain the finished product.
Reaction equation: CH3CH2CH2CH2OH+NaBr+H2SO4→CH3CH2CH2CH2Br+Na2SO4+H2O
This halide is easily prepared by reacting butan-1-ol (primary alcohol) with sodium bromide solution and excess of concentrated sulfuric acid. The reaction between sodium bromide and sulphuric acid origins hydrobromic acid.
운송 방법
UN1126 & UN23391- & 2-Bromobutane, Hazard Class: 3; Labels: 3—Flammable liquid.Purification Methods
Wash the bromide with conc H2SO4, water, 10% Na2CO3 and again with H2O. Dry it over CaCl2, CaSO4 or K2CO3, and distil it. Redistil it after drying with P2O5, or pass it through two columns containing 5:1 silica gel/Celite mixture and store it with freshly activated alumina. [Beilstein 1 IV 258.]비 호환성
Vapor may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. May accumulate static electrical charges and cause ignition of its vapors.폐기물 처리
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed브롬화부틸 준비 용품 및 원자재
원자재
준비 용품
Benzonatate
옥텐(시스-3-)-1-올
부틸술파이드
Fluorescent Brightener 185
DIMETHIRIMOL
4-N-BUTOXYBENZOIC ACID
트리-n-부틸포스핀
1-Butyl-3-methylimidazolium tetrafluoroborate
메틸(2-)헥사논산
Benoxinate Hydrochloride
디부틸 틴 옥사이드
노르말옥탄
발레로니트릴
펜탄산
아세타미프리드
뷰틸 페닐 에터
N-부틸메르캅탄
노르말에탄올아민
메틸4-메틸티오펜-2-카르복실레이트
부틸(노르말)벤젠
1-Butyl-3-methylimidazolium bromide
1-Butyl-3-methylimidazolium hexafluorophosphate
4-부톡시아닐린
HALOFANTRINE
3-Butoxyphenol
에틸4-(부틸아미노)벤조에이트
1-Butylpiperazine
노르말부틸이소시아네이트
다이-n-뷰틸아민
헥사놀(1-)
에틸2-아세틸헥사노에이트
부틸리튬
4-Methyl-2-thiophenecarboxylic acid
브롬화부틸 공급 업체
글로벌( 620)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Guanlang Biotechnology Co., Ltd. | +8619930503259 |
cherry@crovellbio.com | China | 18430 | 58 |
Shanghai Quedan biology science and technology co., ltd | +86-13004146052 |
lnzc@quedan.com.cn | China | 1060 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12450 | 58 |
Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 |
daisy@crovellbio.com | China | 5828 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 994 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20294 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Yancheng Longshen Chemical Co.,Ltd. | +86-0515-88706880; +8618352073383 |
sales@longshenchem.com | China | 79 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |