ChemicalBook >제품 카탈로그 >화학 시약>유기 시약>토실 레이트>2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate

2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate

2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate 구조식 이미지

카스 번호:: 164162-36-1

상품명:: 2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate

동의어(영문):: Everolimus Impurity 12;Everolimus intermediate A2(Z);2-(tert-Butydilethylsily) oxyethyl;2-(t-ButyldiMethylsilyl)oxyethyl triflate;2-(tert-Butyldimethylsilyloxy)ethyl triflate;2-(t-Butyldimethylsilyloxy)EthylTrifluoromethanesulfonate;2-(tert-butyldiMethylsilyloxy)ethyl trifluoroMethanesulfonate;2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate;2-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}ethyl trifluoromethanesulfonate;Trifluoromethanesulfonic acid 2-[[(tert-butyl)dimethylsilyl]oxy]ethyl ester

CBNumber:: CB12542770

분자식:: C9H19F3O4SSi

포뮬러 무게:: 308.39

MOL 파일:: 164162-36-1.mol

속성

안전

용도

공급 업체 47

2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate 속성

끓는 점: 253℃

밀도: 1.172

인화점: 107℃

안전

2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate C화학적 특성, 용도, 생산

용도

2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate is used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

The reaction was carried out under a nitrogen atmosphere. TBS- ethylene glycol prepared as per step 1 (85.10g, 0.48 mol) and 2, 6-Lutidine (84.28ml, 0.72 mol) were stirred in n-heptane (425ml) to give a clear solution which was then cooled to -15 to - 25°C. Trifluoromethanesulfonic anhydride (Tf2O) (99.74 ml, 0.590 mol) was added drop-wise over a period of 45 minutes to the n-heptane solution (white precipitate starts to form immediately) while maintaining the reaction at -15 to -25°C. The reaction mixture was kept at temperature between -15 to -25°C for 2 hours. The precipitate generated was filtered off. The filtrate was then evaporated up to ~2 volumes with respect to TBS-ethyiene glycol (~200 ml).

2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate 준비 용품 및 원자재

원자재

준비 용품

40-O-[2-(t-butyldimethylsilyl)oxy]ethyl rapamycin

2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate 공급 업체

글로벌( 47)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15954	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21687	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32715	60
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9641	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	info@afinechem.com	China	15396	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
Nanjing Fred Technology Co., Ltd	+86-25-84696168 +86-15380713688	Austin@fredbio.com	China	2427	58

2-(tert-butyldiMethylsilyl )oxyl alcohol trifluorin Methanesulfonate 관련 검색:

BIS(T-BUTYLDIMETHYLSILOXY)ETHANE Methanesulfonic acid, trifluoro-, 2-hydroxyethyl ester Ethyleneglycol bistriflate Everolimus Ring-Opening Impurity Everolimus Impurity 1 Everolimus Related Compound 3 Rapamycin EveroliMus-d4 Everolimus 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone EveroliMus iMpurity Everolimus O-Ethyl Impurity Everolimus Related Compound 2