3-클로로-1-프로판올
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3-클로로-1-프로판올 속성
- 녹는점
- -20 °C
- 끓는 점
- 160-162 °C(lit.)
- 밀도
- 1.131 g/mL at 25 °C(lit.)
- 굴절률
- n
20/D 1.445(lit.)
- 인화점
- 164 °F
- 저장 조건
- 0-6°C
- 용해도
- 50g/l(느린 분해)
- 산도 계수 (pKa)
- 14.73±0.10(Predicted)
- 물리적 상태
- 액체
- Specific Gravity
- 1.14
- 색상
- 무색~황색으로 투명함
- 수소이온지수(pH)
- 3-4 (100g/l, H2O, 20℃)
- 수용성
- 300 g/L (20 ºC)
- BRN
- 773655
- 노출 한도
- No exposure limit is set. A TLV-TWA air value of 100 ppm (approximately 400 mg/m3) is suggested for this compound.
- 안정성
- 안정성 안정적이지만 빛에 민감합니다. 타기 쉬운. 강한 산화제와 호환되지 않습니다.
- InChIKey
- LAMUXTNQCICZQX-UHFFFAOYSA-N
- CAS 데이터베이스
- 627-30-5(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 22-36/37/38 | ||
안전지침서 | 26-36-36/37/39 | ||
유엔번호(UN No.) | UN 2849 6.1/PG 3 | ||
WGK 독일 | 3 | ||
RTECS 번호 | UA8930000 | ||
TSCA | Yes | ||
위험 등급 | 6.1 | ||
포장분류 | III | ||
HS 번호 | 29055910 | ||
기존화학 물질 | KE-05877 |
3-클로로-1-프로판올 C화학적 특성, 용도, 생산
화학적 성질
Colorless to pale-yellow liquid; characteristic odor. Soluble in water, alcohols, and ethers; insoluble in hydrocarbons. Combustible.용도
3-Chloro-1-propanol is used in organicsynthesis to produce cyclopropane andtrimethylene oxide. It is an intermediate inthe synthesis of pharmaceuticals, agrochemicals, antiseptic agents, and dyes. It is an inhibitor of triosephosphate isomerase and glyceraldehyde 3-phosphate dehydrogenase.제조 방법
3-Chloro-1-propanol is synthesized by the reaction of 1, 3-propanediol and hydrochloric acid, using benzene sulfonic acid as the catalyst.Reaction: 250 g of trimethylene glycol are shaken with 450 g of sulfur chloride, the mixture becoming warm, sulfur dioxide being rapidly evolved, and sulfur deposited. This reaction continues for 1 hours without heating, whereafter the mixture is heated for a further 6 hours on the water-bath and then for 30 min, over a free flame. When no more sulfur dioxide is evolved, the mixture is allowed to cool, then extracted several times with ether. The sulfur is washed with ether, and the united ethereal layers are shaken with sodium carbonate solution to remove sulfur dioxide, dried over sodium sulfate, and freed from ether. The residue is fractionated and the fraction of b.p. 140-180° C is redistilled, giving 60% (160 g) of 3-chloro-1-propanol, b.p. 160-164°C/760 mm, 60-64° C/10 mm.
J. Amer. Chem. Soc, 38, 2481 (1916)
J. Chem. Soc, 1928, 2439
일반 설명
3-Chloro-1-propanol appears as a colorless liquid with a mild odor. Slightly denser than water. Toxic by ingestion and inhalation . Flash point 270°F. Used to make plastics, resins and other chemicals.반응 프로필
3-Chloro-1-propanol may be sensitive to prolonged exposure to light. 3-Chloro-1-propanol may react with oxidizing agents. .건강위험
3-Chloro-1-propanol also know as Trimethylene chlorohydrin, is a moderatelytoxic compound. Skin contact can cause irritation.Ingestion can result in CNSdepression, muscle contraction, gastrointesti nal pain, and ulceration or stomach bleed ing. High dosage can cause liver injury. Thetoxicity of this compound, however, is lesssevere than that of its isomer, propylene β-chlorohydrin.LD50 value, oral (mice): 2300 mg/kg
화재위험
Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.Safety Profile
Moderately toxic by ingestion. Mutation data reported. Chloropropanols have mutagenic and carcinogenic properties. The 3-monochloropropanol (3-MCPD) is the main chloropropanol found in hydrolyzates of vegetable protein (HVP) made by acid hydrolysis.폐기물 처리
Trimethylene chlorohydrin is burned in achemical incinerator equipped with an afterburner and scrubber.3-클로로-1-프로판올 준비 용품 및 원자재
원자재
준비 용품
9-(3-(CIS-3 5-DIMETHYL-1-PIPERAZINYL)-
베타-클로로프로피온산
1,5-디아자비시클로[4.3.0]논-5-엔
Mivacurium chloride
4-(3-MORPHOLINOPROPOXY)-3,5-DICHLOROBENZENAMINE
프로필렌 카보네이트
9-비닐안트라센
트리메틸렌옥사이드
글리시딜메틸에테르
3-Chloropropyl acetate
1-클로로-2-프로탄올
1-클로로-3-(톨렌-P-술포닐옥시)프로판
3-(3-HYDROXY-PROPYLAMINO)-PROPAN-1-OL
3-요오도프로판올
1-(3-하이드록시프로필)-4-메틸피페라진
3-플루오로프로판-1-OL
3-Phenoxy-1-propanol
1-(3-하이드록시프로필)-1H-이미다졸
프로필렌글리콜n-부틸에테르
3-(2-methyl-1H-imidazol-1-yl)propan-1-ol(SALTDATA: HCl)
3-클로로-1-프로판올 공급 업체
글로벌( 383)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hubei Ipure Biology Co., Ltd | +8613367258412 |
ada@ipurechemical.com | China | 10326 | 58 |
Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 |
1026@dideu.com | China | 8672 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12495 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5873 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5895 | 58 |
Taixing Foreign Trade Nanjing Co., Ltd. | +86-025-83346564; +8613182976929 |
sales@tx-chem.com | China | 122 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21663 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9284 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 |
info@tnjchem.com | China | 2989 | 55 |