Fmoc-GGFG-Dxd

Fmoc-GGFG-Dxd 구조식 이미지
카스 번호:
1599440-11-5
상품명:
Fmoc-GGFG-Dxd
동의어(영문):
Fmoc-GGFG-Dxd;Exatecan-2-(aminomethoxy)acetamide-Gly-Phe-Gly-Gly-Fmoc;Glycinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycylglycyl-L-phenylalanyl-N-[[2-[[(1S,9S)-9-ethyl-5-fluoro-2,3,9,10,13,15-hexahydro-9-hydroxy-4-methyl-10,13-dioxo-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl]amino]-2-oxoethoxy]methyl]-;(S)-2-[2-[2-(Fmoc-amino)acetamido]acetamido]-N-[2-[[[2-[[(1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-1,2,3,9,10,12,13,15-octahydrobenzo[de]pyrano[3’,4’:6,7]indolizino[1,2-b]quinolin-1-yl]amino]-2-oxoethoxy]methyl]amino]-2-oxoethyl]-3-phenylpropanamide
CBNumber:
CB29806179
분자식:
C57H55FN8O12
포뮬러 무게:
1063.09
MOL 파일:
1599440-11-5.mol

Fmoc-GGFG-Dxd 속성

밀도
1.49±0.1 g/cm3(Predicted)
산도 계수 (pKa)
10.61±0.46(Predicted)

안전

Fmoc-GGFG-Dxd C화학적 특성, 용도, 생산

개요

Fmoc-GGFG-Dxd, also known as N-((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)-2-hydroxyacetamide, is a brown powder. It is a hexacyclic chemical compound analogous to camptothecin with a triplet amino acid chain linked to a terminal Fmoc group. GGFG (glycyl-glycyl-phenylalanyl-glycine peptide could link exatecan derivative (DXd) through cysteine residues. DXd is highly membrane-permeable and exhibited strong bystander killing in-vitro co-culture of HER2 positive (KPL-4) and negative (MDA-MB-468) cells and in mice inoculated with a mixture of HER2 (+) and HER2 (?) cells.
Fmoc-GGFG-Dxd

Fmoc-GGFG-Dxd 준비 용품 및 원자재

원자재

준비 용품


Fmoc-GGFG-Dxd 공급 업체

글로벌( 11)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Xilinglab Co., Ltd.
+8618381337976
bd@xilinglab.com China 86 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58
Shanghai Tekanbio Pharm-Tech Co., Ltd. 021-50896099 18017206244
sales@tekanbio.com China 109 58
BioPharmaMatrix,Inc. 0510-86010668
sales@biopharmamatrix.com China 4074 55
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136
Sales@ATKchemical.com China 7045 58
Shochem(Shanghai)Co.,Ltd +86-021-51783479 +86-13816874662
info@shochem.com China 311 58
Shanghai Easy CDMO Co.,Ltd 021-61734564
August@easycdmo.com China 10031 58
Shaoyuan Technology (Shanghai) Co., Ltd. 021-50795510 4000665055
sy-c6@accelachem.com China 10000 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203
ET-market@chemextension.com China 25737 58
SuZhou GoodChemTech Co., Ltd 18136139868
jinlun@goodchemtech.cn China 221 58

Copyright 2019 © ChemicalBook. All rights reserved