Tenidap

Tenidap 구조식 이미지
카스 번호:
120210-48-2
상품명:
Tenidap
동의어(영문):
TENIDAP;AKOS 91367;TENIDAP USP/EP/BP;CP66248,CP-66248-2;5-Chloro-2,3-dihydro-2-oxo-3-(2-thenoyl)-1H-indole-1-carboxamide;(Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H- indole-1-carboxaMide;(3Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H-indole-1-carboxaMide;1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (3Z)-
CBNumber:
CB3121977
분자식:
C14H9ClN2O3S
포뮬러 무게:
320.75
MOL 파일:
120210-48-2.mol
MSDS 파일:
SDS

Tenidap 속성

녹는점
230° (dec)
끓는 점
538.1±60.0 °C(Predicted)
밀도
1.648±0.06 g/cm3(Predicted)
저장 조건
Store at +4°C
용해도
DMSO: 용해성 1mg/mL, 투명(가온)
물리적 상태
가루
산도 계수 (pKa)
4.50±1.00(Predicted)
색상
희미한 노란색에서 어두운 노란색까지
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn
위험 카페고리 넘버 22
WGK 독일 3
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
예방조치문구:
NFPA 704
0
2 0

Tenidap C화학적 특성, 용도, 생산

용도

Tenidap is one of the nonsteroidal antiinflammatory drugs (NSAIDs). Tenidap is an NSAID that preferentially inhibits COX-1. Tenidap inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes.

생물학적 활성

NSAID that preferentially inhibits COX-1 (IC 50 values are < 0.03, 1.2 and > 30 μ M for COX-1, COX-2 and 5-lipoxygenase respectively). Inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes. Opener of inward rectifying hK IR 2.3 channel (EC 50 = 402 nM).

Mode of action

Tenidap is an anti-inflammatory agent developed by Pfizer with a unique structure that is different and distinguishable from NSAIDs. The mechanism of action of tenidap is that it has dual inhibitory effects on lipoxygenase and dioxygenase, and has antagonism on interleukin-1 (IL-1).

Tenidap 준비 용품 및 원자재

원자재

준비 용품


Tenidap 공급 업체

글로벌( 71)공급 업체
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Hubei xin bonus chemical co. LTD
86-13657291602
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TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 25961 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
info@afinechem.com China 15395 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 990 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52927 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 94717 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15848 69
LGM Pharma 1-(800)-881-8210
inquiries@lgmpharma.com United States 2127 70
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32344 50

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