티엔펩틴

티엔펩틴
티엔펩틴 구조식 이미지
카스 번호:
66981-73-5
한글명:
티엔펩틴
동의어(한글):
티엔펩틴
상품명:
Tianeptine
동의어(영문):
Tianeptine hemisulfate monohydrate;Tianeptineacid;Tianeptine powder;COAXIL;Tianepine;Tianeptina;Tianeotine;Brn 1232295;Tianeptinum;Thioneptine
CBNumber:
CB3217470
분자식:
C21H25ClN2O4S
포뮬러 무게:
436.95
MOL 파일:
66981-73-5.mol

티엔펩틴 속성

녹는점
129-131°C
저장 조건
Hygroscopic, -20°C Freezer, Under inert atmosphere
용해도
물, 메탄올 및 염화메틸렌에 자유롭게 용해됩니다.
물리적 상태
고체
물리적 상태
단단한 모양
색상
흰색에서 황백색까지
InChIKey
JICJBGPOMZQUBB-UHFFFAOYSA-N
SMILES
C(O)(=O)CCCCCCNC1C2=CC=C(Cl)C=C2S(=O)(=O)N(C)C2=CC=CC=C21
CAS 데이터베이스
66981-73-5(CAS DataBase Reference)

안전

유엔번호(UN No.) 3249
위험 등급 6.1(b)
포장분류 III

티엔펩틴 C화학적 특성, 용도, 생산

개요

Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake and is similar to amineptine. Tianeptine does not have a noted effect on monoamine uptake.

화학적 성질

White Solid

용도

Tianeptine is used in the treatment of reactive and neurotic depression, as well as in the treatment of anxious states.

용도

Tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant

생물학적 활성

Tianeptine was identified as an efficacious MOR full agonist, binding to the human MOR with a Ki of 383 ± 183 nM. Tianeptine was also found to act as a full agonist at the DOR, although it had much lower potency and was inactive at the KOR. The MOR was required for the acute and chronic antidepressant-like effects of tianeptine in mice. Although tianeptine also produced behavioural effects, including analgesia and reward, its effects were distinct from morphine in that it did not produce tolerance or withdrawal.

티엔펩틴 준비 용품 및 원자재

원자재

준비 용품


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