아세트아마이드

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아세트아마이드 MSDS

Ethanamide

아세트아마이드 C화학적 특성, 용도, 생산

개요

아세트 아미드는 아세트산으로부터 유도 된 아미드이다. 순수한 생성물은 실온에서 백색 결정질 고체이며, 아세트산 암모늄의 탈수에 의해 수득 될 수있다. 그것은 가소제 및 유기 합성의 중요한 원료로 사용됩니다.

용도

"1. 용융 아세트 아미드는 다양한 유기 및 무기 물질을위한 우수한 용매입니다. 섬유 산업에서 염료로 사용되는 용제 및 용해제와 같이 수용성이 낮은 물질을 물에 용해시킬 때 용해 보조제로 사용할 수 있습니다. 또한 가소제의 안정제, 화장품 산업의 제산제, 제지 산업의 습윤제 및 chloramphenicol과 같은 항생제 합성 용제로 널리 사용됩니다. 2. 분석 시약, 용제, 안정제, 가소제로 사용됩니다. 또한 유기 합성, 제약 산업, 염료 제조에도 사용할 수 있습니다. 3. 흡습제, 윤활제 등의 제조에도 사용됩니다."

제품 소개

아세트 아미드는 매우 인화성이 없지만 화상을 입으면 자극적 인 흄을 방출합니다. 흡입, 섭취, 피부 및 눈 접촉은 유독하며 피부와 눈 접촉은 발적 또는 통증을 유발할 수 있습니다.

개요

Acetamide (MEA or ethanamide), the amide of acetic acid, is a white crystalline solid in pure form with a mousy odor. Low toxicity. It is produced by dehydrating ammonium acetate. Acetamide is found in red beetroot.
Acetamide is used primarily as a solvent, plasticizer, and a wetting and penetrating agent. it was used as an intermediate in the synthesis of methylamine, thioacetamide, hypnotics, insecticides, medicinals and various plastics, a soldering flux ingredient, a wetting agent and penetration accelerator for dyes, and as a plasticizer in leather, cloth and coatings.
ethanolamine is an amide made from acetamide and monoethanolamine. It is a clear liquid. In cosmetics and personal care products, It is used in the formulation of bubble baths, hair conditioners, shampoos, wave sets, moisturizers, and other bath and hair care products.It increases the water content of the top layers of the skin by drawing moisture from the surrounding air. It also enhances the appearance and feel of hair, by increasing hair body, suppleness, or sheen, or by improving the texture of hair that has been damaged physically or by chemical treatment.

화학적 성질

Acetamide occurs as hexagonal colourless deliquescent crystals with a musty odour. It is incompatible with strong acids, strong oxidising agents, strong bases, and triboluminescent materials. Acetamide is used primarily as a solvent, a plasticiser, and a wetting and penetrating agent. Workplace exposures to acetamide are associated with the plastic and chemical industries.

용도

1. Acetamide is often used as plasticizer and as industrial solvent.
2. molten acetamide is an excellent solvent for many organic and inorganic compounds.
3. Solubilizer.
4. renders sparingly soluble substances more soluble in water by mere addition or by fusion.
5. stabilizer.
6. manufacture of methylamine, denaturing alcohol.
7. In organic syntheses.
8. Acetamide is used as a co-monomer in the production of polymeric materials such as polyvinyl acetamide, a polymeric product used as an absorbent.
9. It can be used for the transamidation of carbxamides in 1,4-dioxane in the absence of a catalyst.

일반 설명

Colorless crystals with a mousy odor (NTP, 1999). Low toxicity.

공기와 물의 반응

Deliquescent. Very soluble in water.

반응 프로필

Acetamide may react with azo and diazo compounds to generate toxic gases. May form flammable gases with strong reducing agents. Reacts as a weak bases (weaker than water). Mixing with dehydrating agents such as P2O5 or SOCl2 generates acetonitrile Burns to give toxic mixed oxides of nitrogen (NOx).

건강위험

After oral exposures to acetamide, animals developed liver tumors. However, no informa- tion is available on the carcinogenic effects of acetamide in humans. The US EPA has not classifi ed acetamide for carcinogenicity. The IARC has classifi ed acetamide as a Group 2B, meaning a possible human carcinogen.

화재위험

The flash point of Acetamide has not been determined, but Acetamide is probably combustible.

Safety Profile

Suspected carcinogen with experimental carcinogenic and neoplastigenic data. Moderately toxic by intraperitoneal and possibly other routes. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. See also AMIDES. When heated to decomposition it emits toxic fumes of NOx,.

잠재적 노출

Used as a stabilizer, plasticizer, wetting agent; solvent in plastics, lacquers, explosive; soldering flux ingredient; and chemical manufacturing

Carcinogenicity

The IARC has determined that there is sufficient evidence of carcinogenicity for acetamide in experimental animals and that it is possibly carcinogenic to humans.

환경귀착

The mechanism of toxicity of acetamide is not known; the response profile is quite different from the better studied dimethyl derivative. Acetamide appears to be in a class of chemicals which, although producing liver cancer in rodents, is less sensitive to inactive in genetic tests looking at formation of micronuclei. The carcinogenic response in rodents appears related to the formation of hydroxylamine from the primary metabolite acetohydroxamic acid.

저장

Acetamide should be kept stored in a tightly closed container, in a cool, dry, ventilated area. It should be protected against physical damage, away from any source of heat, ignition, or oxidizing materials.

운송 방법

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required

Purification Methods

Acetamide is crystallised by dissolving in hot MeOH (0.8mL/g), diluting with Et2O and allowing to stand [Wagner J Chem Edu 7 1135 1930]. Alternate crystallisation solvents are acetone, *benzene, chloroform, dioxane, methyl acetate or *benzene/ethyl acetate mixtures (3:1 and 1:1). It has also been recrystallised from hot water after treating with HCl-washed activated charcoal (which had been repeatedly washed with water until free from chloride ions), then crystallised again from hot 50% aqueous EtOH and finally twice from hot 95% EtOH [Christoffers & Kegeles J Am Chem Soc 85 2562 1963]. Finally it is dried in a vacuum desiccator over P2O5. Acetamide is also purified by distillation (b 221-223o) or by sublimation in vacuo. It has also been purified by two recrystallisations from cyclohexane containing 5% (v/v) of *benzene. Needle-like crystals separate and are filtered, washed with a small volume of distilled H2O and dried with a flow of dry N2. [Slebocka-Tilk et al. J Am Chem Soc 109 4620 1987, Beilstein 2 H 175, 2 I 80, 2 II 177, 2 III 384, 2 IV 399.]

비 호환성

Reacts with strong acids, such as hydrochloric, sulfuric, and nitric, strong oxidizers; strong bases; strong reducing agents such as hydrides; ammoniaisocyanates, phenols, cresols. Contact with water causes slow hydrolyzation to ammonia and acetate salts.

폐기물 처리

Add to alcohol or benzene as a flammable solvent and incinerate; oxides of nitrogen produced may be scrubbed out with alkaline solution. All federal, state, and local environmental regulations must be observed.

주의 사항

During handling and/use of acetamide, workers should wear special protective equipment. After leaving work areas, workers should wash hands, face, forearms, and neck, dispose of outer clothing, and change to clean garments at the end of the day.

아세트아마이드 준비 용품 및 원자재

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아세트아마이드 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Honest Joy Holdings Limited	0755-36694831 +8613717124449	sale@feiyang.com.cn	China	300	58
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12837	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5893	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20288	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3002	58
Hebei Shengyang Water Conservancy Engineering Co., Ltd.	+8615373025980	clara@hbshengyang.com	China	874	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21639	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1803	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32820	60

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