HPI-1수화물

HPI-1수화물
HPI-1수화물 구조식 이미지
카스 번호:
1262770-72-8
한글명:
HPI-1수화물
동의어(한글):
HPI-1수화물
상품명:
HPI-1 Hydrate
동의어(영문):
HPI-1 Hydrate;1,4,5,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7-(2-Methoxyphenyl)-2-Methyl-5-oxo-3-quinolinecarboxylic Acid 2-Methoxyethyl Ester Hydrate
CBNumber:
CB42545196
분자식:
C27H31NO7
포뮬러 무게:
481.53754
MOL 파일:
1262770-72-8.mol

HPI-1수화물 속성

안전

HPI-1수화물 C화학적 특성, 용도, 생산

개요

HPI-1 (hydrate) is a Hedgehog (Hh) pathway inhibitor that suppresses signaling through Sonic Hh (IC50 = 1.5 μM) without significantly affecting Wnt signaling (IC50 ≥ 30 μM). HPI-1 suppresses Hh activation induced by loss of Suppressor of Fused or by Gli overexpression, suggesting action at posttranslational modification of Gli protein or at the interaction of Gli with a co-factor. HPI-1 (hydrate) also inhibits signaling through the oncogenic Smoothened (Smo) mutant SmoM2 in neuron precursors, preventing cell proliferation.

용도

HPI-1 is a Hedgehog pathway inhibitor; Gli1/Gli2 inhibitor.

HPI-1수화물 준비 용품 및 원자재

원자재

준비 용품


HPI-1수화물 공급 업체

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