HPI-1 Hydrate
- CAS No.
- 1262770-72-8
- Chemical Name:
- HPI-1 Hydrate
- Synonyms
- HPI-1 Hydrate;1,4,5,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7-(2-Methoxyphenyl)-2-Methyl-5-oxo-3-quinolinecarboxylic Acid 2-Methoxyethyl Ester Hydrate
- CBNumber:
- CB42545196
- Molecular Formula:
- C27H31NO7
- Molecular Weight:
- 481.53754
- MDL Number:
- MOL File:
- 1262770-72-8.mol
HPI-1 Hydrate price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 15221 | HPI-1 (hydrate) | 1262770-72-8 | 5mg | $106 | 2024-03-01 | Buy |
| Cayman Chemical | 15221 | HPI-1 (hydrate) | 1262770-72-8 | 50mg | $775 | 2024-03-01 | Buy |
| Cayman Chemical | 15221 | HPI-1 (hydrate) | 1262770-72-8 | 10mg | $187 | 2024-03-01 | Buy |
| Cayman Chemical | 15221 | HPI-1 (hydrate) | 1262770-72-8 | 25mg | $440 | 2024-03-01 | Buy |
| TRC | H671250 | HPI-1 hydrate | 1262770-72-8 | 25mg | $130 | 2021-12-16 | Buy |
HPI-1 Hydrate Chemical Properties,Uses,Production
Description
HPI-1 (hydrate) is a Hedgehog (Hh) pathway inhibitor that suppresses signaling through Sonic Hh (IC50 = 1.5 μM) without significantly affecting Wnt signaling (IC50 ≥ 30 μM). HPI-1 suppresses Hh activation induced by loss of Suppressor of Fused or by Gli overexpression, suggesting action at posttranslational modification of Gli protein or at the interaction of Gli with a co-factor. HPI-1 (hydrate) also inhibits signaling through the oncogenic Smoothened (Smo) mutant SmoM2 in neuron precursors, preventing cell proliferation.
Uses
HPI-1 is a Hedgehog pathway inhibitor; Gli1/Gli2 inhibitor.
HPI-1 Hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
HPI-1 Hydrate Suppliers
Global( 17)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 56068 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
HPI-1 Hydrate
1,4,5,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7-(2-Methoxyphenyl)-2-Methyl-5-oxo-3-quinolinecarboxylic Acid 2-Methoxyethyl Ester Hydrate
1262770-72-8
Aromatics
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals
Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals